Catalog No.
PVV29401
Species reactivity
Human metapneumovirus (strain CAN97-83) (HMPV)
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant HMPV G/Major surface glycoprotein G (Asn52-Asn219).
Tested applications
ELISA: 1:4000-1:8000, IHC:1:50-1:200, WB: 1:1000-1:4000
Target
Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, G
Concentration
1.03 mg/ml
Purification
Purified by antigen affinity column.
Accession
Q6WB94
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
A potently neutralizing and protective human antibody targeting antigenic site V on RSV and hMPV fusion glycoprotein., PMID:39554078
Characterization of prefusion-F-specific antibodies elicited by natural infection with human metapneumovirus., PMID:36130517
Role of human metapneumovirus glycoprotein G in modulation of immune responses., PMID:35958551
Profiling of hMPV F-specific antibodies isolated from human memory B cells., PMID:35538099
Roles of the putative integrin-binding motif of the human metapneumovirus fusion (f) protein in cell-cell fusion, viral infectivity, and pathogenesis., PMID:24478423
Genetic diversity and molecular evolution of the major human metapneumovirus surface glycoproteins over a decade., PMID:24041471
Immunogenicity in mice of human metapneumovirus with a truncated SH glycoprotein., PMID:24009128
Virus-like particle vaccine induces cross-protection against human metapneumovirus infections in mice., PMID:23583815
Soluble recombinant human metapneumovirus G protein is immunogenic but not protective., PMID:20417260
An alphavirus replicon-based human metapneumovirus vaccine is immunogenic and protective in mice and cotton rats., PMID:18786987
Detection of four genetic subgroup-specific antibodies to human metapneumovirus attachment (G) protein in human serum., PMID:18632969
Individual contributions of the human metapneumovirus F, G, and SH surface glycoproteins to the induction of neutralizing antibodies and protective immunity., PMID:16300813
Recombinant human Metapneumovirus lacking the small hydrophobic SH and/or attachment G glycoprotein: deletion of G yields a promising vaccine candidate., PMID:15542640
High genetic diversity of the attachment (G) protein of human metapneumovirus., PMID:15297475