Catalog No.
DHD88702
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
M3S1, Tumor-associated antigen L6, TAAL6, Membrane component chromosome 3 surface marker 1, TM4SF1, Transmembrane 4 L6 family member 1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P30408
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
hAGX-A01H1L10
PLAU promotes growth and attenuates cisplatin chemosensitivity in ARID1A-depleted non-small cell lung cancer through interaction with TM4SF1., PMID:38229120
Three Members of Transmembrane-4-Superfamily, TM4SF1, TM4SF4, and TM4SF5, as Emerging Anticancer Molecular Targets against Cancer Phenotypes and Chemoresistance., PMID:36678607
A combined biomarker panel shows improved sensitivity and specificity for detection of ovarian cancer., PMID:34995016
Role of Transmembrane 4 L Six Family 1 in the Development and Progression of Cancer., PMID:33015133
Endoplasmic reticulum-targeting sequence enhanced the cellular immunity of a tumor-associated antigen L6-based DNA vaccine., PMID:31598403
Tumors: Wounds That Do Not Heal-A Historical Perspective with a Focus on the Fundamental Roles of Increased Vascular Permeability and Clotting., PMID:31096305
Clinical significance of TM4SF1 as a tumor suppressor gene in gastric cancer., PMID:29665316
[Clinical validation of multiple biomarkers suspension array technology for ovarian cancer]., PMID:28190310
[Establishment and verification of detecting multiple biomarkers for ovarian cancer by suspension array technology]., PMID:27788745
Chimeric peptide containing both B and T cells epitope of tumor-associated antigen L6 enhances anti-tumor effects in HLA-A2 transgenic mice., PMID:27130449
ADAM23 is downregulated in side population and suppresses lung metastasis of lung carcinoma cells., PMID:26800504
Intracellular distribution of TM4SF1 and internalization of TM4SF1-antibody complex in vascular endothelial cells., PMID:26241677
Novel Anti-TM4SF1 Antibody-Drug Conjugates with Activity against Tumor Cells and Tumor Vasculature., PMID:26089370
TM4SF4 overexpression in radiation-resistant lung carcinoma cells activates IGF1R via elevation of IGF1., PMID:25344917
TM4SF1: a new vascular therapeutic target in cancer., PMID:24986520
[Clinical study of autoantibody spectrum against ovarian cancer associated antigens combined with CA(125) in detecting and monitoring ovarian cancer]., PMID:21426769
The tumour-associated antigen L6 (L6-Ag) is recruited to the tetraspanin-enriched microdomains: implication for tumour cell motility., PMID:18270265
CD13 (aminopeptidase N) can associate with tumor-associated antigen L6 and enhance the motility of human lung cancer cells., PMID:15812828
Tumor-associated antigen L6 and the invasion of human lung cancer cells., PMID:12855661
Molecular and functional characterization of the four-transmembrane molecule l6 in epidermal keratinocytes., PMID:11426942
Therapeutic effects of monoclonal antibody-beta-lactamase conjugates in combination with a nitrogen mustard anticancer prodrug in models of human renal cell carcinoma., PMID:9554883
Costimulation by CD28 sFv expressed on the tumor cell surface or as a soluble bispecific molecule targeted to the L6 carcinoma antigen., PMID:8946677
Cloning of the murine counterpart of the tumor-associated antigen H-L6: epitope mapping of the human and murine L6 antigens., PMID:7548016
Identification of residues in the monoclonal antitumor antibody L6 important for binding to its tumor antigen., PMID:7526900
Effect of CTLA-4 chimeric protein on rat autoimmune anti-glomerular basement membrane glomerulonephritis., PMID:8206086
Membrane topology of the L6 antigen and identification of the protein epitope recognized by the L6 monoclonal antibody., PMID:7510285
Improving radioimmonotargeting of tumors. Variation in the amount of L6 MAb administered, combined with an immunoadsorption system (ECIA)., PMID:8305236
Cloning and expression of the tumor-associated antigen L6., PMID:1565644
For research use only. Not for human or drug use.
