Catalog No.
DHJ22704
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
CRF2-9, IL-22RA1, IL22RA1, ZcytoR11, IL-22R-alpha-1, IL-22 receptor subunit alpha-1, Cytokine receptor class-II member 9, Interleukin-22 receptor subunit alpha-1, Cytokine receptor family 2 member 9, IL22R
Concentration
1.48 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q8N6P7
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Alternative Names
ARGX-112, ARGX112, ARGX 112
Clone ID
ARGX-112
IL-22/IL-22RA1 Promotes Human Tenon's Capsule Fibroblasts Proliferation and Regulates Fibrosis Through STAT3 Signaling Pathway., PMID:39046932
Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis., PMID:38811550
Identification of a Prognostic Signature Composed of GPI, IL22RA1, CCT6A and SPOCK1 for Lung Adenocarcinoma Based on Bioinformatic Analysis of lncRNA-Mediated ceRNA Network and Sample Validation., PMID:35433415
Blockade of IL-22 signaling reverses erythroid dysfunction in stress-induced anemias., PMID:33753942
Interleukin 22 mitigates endothelial glycocalyx shedding after lipopolysaccharide injury., PMID:33502147
Enhanced Type 2 Immune Reactions by Increased IL-22/IL-22Ra1 Signaling in Chronic Rhinosinusitis With Nasal Polyps., PMID:32935490
Oral epithelial IL-22/STAT3 signaling licenses IL-17-mediated immunity to oral mucosal candidiasis., PMID:32503875
IL-24 contributes to skin inflammation in Para-Phenylenediamine-induced contact hypersensitivity., PMID:30755657
The IL-20 Cytokine Family in Rheumatoid Arthritis and Spondyloarthritis., PMID:30319661
Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis., PMID:27769811
Cyclosporine A immunosuppression drives catastrophic squamous cell carcinoma through IL-22., PMID:27699266
Differential Requirements for IL-17A and IL-22 in Cecal versus Colonic Inflammation Induced by Helicobacter hepaticus., PMID:26458765
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival., PMID:26155400
Ustekinumab improves psoriasis-related gene expression in noninvolved psoriatic skin without inhibition of the antimicrobial response., PMID:23278632
Aryl hydrocarbon receptor regulates pancreatic IL-22 production and protects mice from acute pancreatitis., PMID:23022954
Bovine IFNGR2, IL12RB1, IL12RB2, and IL23R polymorphisms and MAP infection status., PMID:21597988
IL-22, in contrast to IL-10, does not induce Ig production, due to absence of a functional IL-22 receptor on activated human B cells., PMID:12407026
For research use only. Not for human or drug use.
