Catalog No.
DHF11805
Expression system
Mammalian Cells
Species reactivity
Human
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
K-cadherin, CDH6, Cadherin-6, Kidney cadherin
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P55285
Applications
Research Grade Biosimilar
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
H01L02
Antibody-drug conjugates as targeted therapy for treating gynecologic cancers: update 2025., PMID:39480912
PAX8 expression in cancerous and non-neoplastic tissue: a tissue microarray study on more than 17,000 tumors from 149 different tumor entities., PMID:39105782
Neurotensin modulates ovarian vascular permeability via adherens junctions., PMID:38581236
Raludotatug Deruxtecan, a CDH6-Targeting Antibody-Drug Conjugate with a DNA Topoisomerase I Inhibitor DXd, Is Efficacious in Human Ovarian and Kidney Cancer Models., PMID:38205802
A Phase 1 Study of a CDH6-Targeting Antibody-Drug Conjugate in Patients with Advanced Solid Tumors with Evaluation of Inflammatory and Neurological Adverse Events., PMID:34515215
CDH6-activated αIIbβ3 crosstalks with α2β1 to trigger cellular adhesion and invasion in metastatic ovarian and renal cancers., PMID:33715292
Murine cadherin-6 mediates thrombosis in vivo in a platelet-independent manner., PMID:33537536
Redundant type II cadherins define neuroepithelial cell states for cytoarchitectonic robustness., PMID:33060832
Multi-platform Affinity Proteomics Identify Proteins Linked to Metastasis and Immune Suppression in Ovarian Cancer Plasma., PMID:31737572
Beyond N-Cadherin, Relevance of Cadherins 5, 6 and 17 in Cancer Progression and Metastasis., PMID:31324051
RGD cadherins and α2β1 integrin in cancer metastasis: A dangerous liaison., PMID:29673969
Utilizing panels of patient derived xenografts to aid the development of antibody drug conjugates., PMID:29404392
Discovery and Optimization of HKT288, a Cadherin-6-Targeting ADC for the Treatment of Ovarian and Renal Cancers., PMID:28526733
Cadherin 6 has a functional role in platelet aggregation and thrombus formation., PMID:22539596
Differential gene expression in pristane-induced arthritis susceptible DA versus resistant E3 rats., PMID:14680511
Cadherin-11 modulates the terminal differentiation and fusion of human trophoblastic cells in vitro., PMID:12710956
Complementary expression and regulation of cadherins 6 and 11 during specific steps of motoneuron differentiation., PMID:12139922
Dynamic testicular adhesion junctions are immunologically unique. II. Localization of classic cadherins in rat testis., PMID:11906918
Alterations in expression of cadherin-6 and E-cadherin during kidney development and in renal cell carcinoma., PMID:10940709
Differential regulation of endogenous cadherin expression in Madin-Darby canine kidney cells by cell-cell adhesion and activation of beta -catenin signaling., PMID:10747916
Differential expression and function of cadherin-6 during renal epithelium development., PMID:9449663
Cadherin-6, a cell adhesion molecule specifically expressed in the proximal renal tubule and renal cell carcinoma., PMID:9205085
For research use only. Not for human or drug use.
