Catalog No.
RHM02815
Species reactivity
Human
Host species
Mouse
Isotype
IgG1
Clonality
Monoclonal
Target
HLA-DRA1, MHC class II antigen DRA, HLA-DRA, HLA class II histocompatibility antigen, DR alpha chain, HLA class II histocompatibility antigen, DRB1 beta chain, Human leukocyte antigen DRB1, HLA-DRB1
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P01903 & P01911
Applications
ELISA, FCM, SPR
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
GPC-8-27
Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation., PMID:40226614
A self-activated and protective module enhances the preclinical performance of allogeneic anti-CD70 CAR-T cells., PMID:39906740
Epigenetic age acceleration and methylation differences in IgG4-related cholangitis and primary sclerosing cholangitis., PMID:39819503
A Genome-Wide Association Study Suggests New Susceptibility Loci for Primary Antiphospholipid Syndrome., PMID:38973605
A protective effect of lower MHC-II expression in MOGAD., PMID:38703720
A genome-wide association study suggests new susceptibility loci for primary antiphospholipid syndrome., PMID:38405993
Increased Frequency of the HLA-DRB1*04:04-DQA1*03-DQB1*03:02 Haplotype Among HLA-DQB1*06:02-Positive Children With Type 1 Diabetes., PMID:37934957
Identification of Distinct Genetic Profiles of Palindromic Rheumatism Using Whole-Exome Sequencing., PMID:37219934
Identification of immune cell infiltration and diagnostic biomarkers in unstable atherosclerotic plaques by integrated bioinformatics analysis and machine learning., PMID:36211422
Single-cell RNA sequencing to decipher the immunogenicity of ChAdOx1 nCoV-19/AZD1222 and mRNA-1273 vaccines in patients with autoimmune rheumatic diseases., PMID:35979368
The Shared Mechanism and Candidate Drugs of Multiple Sclerosis and Sjögren's Syndrome Analyzed by Bioinformatics Based on GWAS and Transcriptome Data., PMID:35356004
Antigen-specific immunotherapy with apitopes suppresses generation of FVIII inhibitor antibodies in HLA-transgenic mice., PMID:34529764
Characterization of human FDCs reveals regulation of T cells and antigen presentation to B cells., PMID:34424268
HLA Alleles and Prognosis of PLA2R-Related Membranous Nephropathy., PMID:34083219
Molecular analysis of phenotypic interactions of asthma., PMID:33849767
High-resolution mapping identifies HLA class II associations with multifocal motor neuropathy., PMID:33582569
Salivary gland epithelial cells from patients with Sjögren's syndrome induce B-lymphocyte survival and activation., PMID:32843324
Clinical Management and Therapeutic Strategies for the Thyroid-Associated Ophthalmopathy: Current and Future Perspectives., PMID:32567373
Foetal and neonatal alloimmune thrombocytopenia - The role of the HLA-DRB3*01:01 allele for HPA-1a-immunisation and foetal/neonatal outcome., PMID:31919011
Early suppression of peripheral mononuclear blood cells in sepsis in response to stimulation with cytomegalovirus, OKT3, and pokeweed mitogen., PMID:31545153
Development of a monoclonal antibody against swine leukocyte antigen (SLA)-DR α chain and evaluation of SLA-DR expression in bone marrow-derived dendritic cells after PRRSV infection., PMID:31084889
Expression estimation and eQTL mapping for HLA genes with a personalized pipeline., PMID:31009447
Immunogenetic Factors of Neurodegenerative Diseases: The Role of HLA Class II., PMID:30472949
FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity., PMID:29444872
Whole-blood RNA transcript-based models can predict clinical response in two large independent clinical studies of patients with advanced melanoma treated with the checkpoint inhibitor, tremelimumab., PMID:28807052
The HLA DRB1*03:01 allele is associated with NMO regardless of the NMO-IgG status in Brazilian patients from Rio de Janeiro., PMID:28778431
PLA2R and THSD7A: Disparate Paths to the Same Disease?, PMID:28674044
Using DR52c/Ni2+ mimotope tetramers to detect Ni2+ reactive CD4+ T cells in patients with joint replacement failure., PMID:28554661
Genetic Predictors of Drug Hypersensitivity., PMID:27779086
T cell responses to human platelet antigen-1a involve a unique form of indirect allorecognition., PMID:27699233
T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire., PMID:27471234
Family study of monozygotic twins affected by pemphigus vulgaris., PMID:27177496
CD28 and PTPN22 are associated with susceptibility to rheumatoid arthritis in Egyptians., PMID:27125674
Genetic variants associated with drugs-induced immediate hypersensitivity reactions: a PRISMA-compliant systematic review., PMID:26678823
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas., PMID:26500140
An Immunochip-based interaction study of contrasting interaction effects with smoking in ACPA-positive versus ACPA-negative rheumatoid arthritis., PMID:26272072
Unintended Consequences of the New National Kidney Allocation Policy in the United States., PMID:26137963
HLA-DRB and HLA-DQ genetic variability in patients with aspirin-exacerbated respiratory disease., PMID:25975240
De novo-developed antibodies to donor MHC antigens lead to dysregulation of microRNAs and induction of MHC class II., PMID:25941328
The dilemma of DQ HLA-antibodies., PMID:25814447
A genome-wide association study of heparin-induced thrombocytopenia using an electronic medical record., PMID:25503805
Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome., PMID:25092888
Genome-wide genetic and transcriptomic investigation of variation in antibody response to dietary antigens., PMID:24962563
Comparable autoantibody serum levels against amyloid- and inflammation-associated proteins in Parkinson's disease patients and controls., PMID:24586351
A novel method to measure HLA-DM-susceptibility of peptides bound to MHC class II molecules based on peptide binding competition assay and differential IC(50) determination., PMID:24583195
Expression of a single-chain human leukocyte antigen-DRA/DRB3*01:01 molecule and differential binding of a monoclonal antibody in the presence of specifically bound human platelet antigen-1a peptide., PMID:24308361
Comparative analysis of gingival tissue antigen presentation pathways in ageing and periodontitis., PMID:24304139
Polar lipids of Burkholderia pseudomallei induce different host immune responses., PMID:24260378
Genetic variants within the MHC region are associated with immune responsiveness to childhood vaccinations., PMID:24075919
HLA-DRB1 shared epitope-dependent DR-DQ haplotypes are associated with both anti-CCP-positive and -negative rheumatoid arthritis in Chinese Han., PMID:23951149
For research use only. Not for human or drug use.
