Anti-Human HLA-A2 Antibody (3PF12)

Catalog No.

RHM02501

Species reactivity

Human

Host species

Mouse

Isotype

IgG1

Clonality

Monoclonal

Target

HLAA, Human leukocyte antigen A, HLA class I histocompatibility antigen, A alpha chain, HLA-A

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P04439

Applications

ELISA, FCM

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

3PF12

Impact of Antibody Immune Response and Immune Cells on Osteoporosis and Fractures., PMID:40454120

T cell receptor mimic CAR T cells targeting cathepsin G signal peptide., PMID:40437170

Targeting intracellular LMP2 with costimulatory signal-armed antibody-like TCR T cells., PMID:40401520

Application of Humanized MHC Transgenic Mice in the Screening of HLA-Restricted T Cell Epitopes for Influenza Vaccines., PMID:40266241

Chimeric anti-HLA antibody receptor engineered human regulatory T cells suppress alloantigen-specific B cells from pre-sensitized transplant recipients., PMID:40236118

CAR Treg synergy with anti-CD154 promotes infectious tolerance and dictates allogeneic heart transplant acceptance., PMID:40197364

Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients., PMID:40170856

Pivotal epitopes for islet antigen-specific CD8+ T cell detection improve classification of suspected type 1 diabetes with the HLA-A*0201 allele., PMID:40133500

A novel method for identifying SARS-CoV-2 infection mutants via an epitope-specific CD8+ T cell test., PMID:40078724

Highlights from the breakout session: vasculitis in paediatric rheumatology., PMID:40071400

First-in-human evaluation of memory-like NK cells with an IL-15 super-agonist and CTLA-4 blockade in advanced head and neck cancer., PMID:39948608

Immunotherapy targeting a leader sequence cathepsin G-derived peptide., PMID:39939820

Differential Clinical and Immunological Impacts of Anti-T-Lymphocyte Globulin (ATLG) vs. Anti-Thymocyte Globulin (ATG) in Preventing Graft-Versus-Host Disease Post-Allogeneic Hematopoietic Stem Cell Transplantation: A Comparative Study., PMID:39905816

Functional and phenotypic profiles of HLA-specific antibodies in relation to antibody-mediated kidney transplant rejection., PMID:39889319

T cell immune evasion by SARS-CoV-2 JN.1 escapees targeting two cytotoxic T cell epitope hotspots., PMID:39875585

Distinct CD8+ T-cell types Associated with COVID-19 Severity in Unvaccinated HLA-A2+ Patients., PMID:39868279

Characterization of a 3S PRAME VLD-Specific T Cell Receptor and Its Use in Investigational Medicinal Products for TCR-T Therapy of Patients with Myeloid Malignancies., PMID:39858024

Exploring red blood cells as an antigen delivery system to modulate the immune response towards FVIII in hemophilia A., PMID:39617188

Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire., PMID:39589869

Safety and Tolerability of Letetresgene Autoleucel (GSK3377794): Pilot Studies in Patients with Advanced Non-Small Cell Lung Cancer., PMID:39576208

Open-Label Phase 1/2 Study of Daratumumab-Based Desensitization Before Kidney Transplantation., PMID:39534185

Finding of celiac disease during the study of Kimura disease in a Caucasian male., PMID:39530579

Implementation of an Immunoassay Based on the MVA-T7pol-Expression System for Rapid Identification of Immunogenic SARS-CoV-2 Antigens: A Proof-of-Concept Study., PMID:39456680

CAR Treg synergy with anti-CD154 mediates infectious tolerance to dictate heart transplant outcomes., PMID:39386649

The Consequences of HLA Screening in the Prevention of Graft-Versus-Host Disease in Living Donor Liver Transplantation., PMID:39177044

Isolation and characterization of stem cells from human exfoliated deciduous teeth., PMID:39132248

TCR-like bispecific antibodies toward eliminating infected hepatocytes in HBV mouse models., PMID:39109538

Investigating the Diagnostic and Therapeutic Potential of a T Cell Receptor (TCR)-like single Domain Antibody (sDAb)-Human IgG1 Antibody against Heat Shock Protein (HSP) 16KDa/HLA-A2 for Latent Tuberculosis., PMID:39058181

Hu8F4-CAR T cells with mutated Fc spacer segment improve target specificity and mediate anti-leukemia activity in vivo., PMID:39033444

Successful A2 to O Simultaneous Liver and Kidney Transplantation in the Setting of Pre-operative Positive HLA Crossmatch: A Case Report., PMID:39004578

First-in-human clinical trial results with ABBV-184, a first-in-class T-cell receptor/anti-CD3 bispecific protein, in adults with previously treated AML or NSCLC., PMID:38946484

The co-occurrence of sarcoidosis and anti-PLA2R-associated membranous nephropathy in a patient with underlying genetic susceptibility., PMID:38937663

Single-cell RNA sequencing revealed the role of the Th17 pathway in the development of anti- human leukocyte antigen antibodies in a highly sensitized mouse model., PMID:38934039

Results of the Phase 1 Open-Label Safety Study of Umbilical Cord Lining Mesenchymal Stromal/Stem Cells (Corlicyte®) to Heal Chronic Diabetic Foot Ulcers., PMID:38927582

Combining SiRPα decoy-coengineered T cells and antibodies augments macrophage-mediated phagocytosis of tumor cells., PMID:38828721

Generation and evaluation of cancer binding capacity of HLA-A2-WT1 complex-targeting antibody., PMID:38810886

Potent antitumor activity of a bispecific T-cell engager antibody targeting the intracellular antigen KRAS G12V., PMID:38752985

Construction and efficacy testing of DNA vaccines containing HLA-A*02:01-restricted SARS-CoV-2 T-cell epitopes predicted by immunoinformatics., PMID:38655616

Enhanced T cell receptor specificity through framework engineering., PMID:38545094

Poor prognostic factors of pharmacokinetic origin predict outcomes in inflammatory bowel disease patients treated with anti-tumor necrosis factor-α., PMID:38476237

Hu8F4-CAR T cells with mutated Fc spacer segment improve target-specificity and mediate anti-leukemia activity in vivo., PMID:38464203

Strong humoral response after Covid-19 vaccination correlates with the common HLA allele A*03:01 and protection from breakthrough infection., PMID:38433722

Combined Use of Tocilizumab and Mesenchymal Stem Cells Attenuate the Development of an Anti-HLA-A2.1 Antibody in a Highly Sensitized Mouse Model., PMID:38338657

Cross-protection induced by highly conserved human B, CD4+, and CD8+ T-cell epitopes-based vaccine against severe infection, disease, and death caused by multiple SARS-CoV-2 variants of concern., PMID:38318166

Tabelecleucel for allogeneic haematopoietic stem-cell or solid organ transplant recipients with Epstein-Barr virus-positive post-transplant lymphoproliferative disease after failure of rituximab or rituximab and chemotherapy (ALLELE): a phase 3, multicentre, open-label trial., PMID:38309282

Abrogation and homeostatic restoration of IgE responses by a universal IgE allergy CTL vaccine-The three signal self/non-self/self (S/NS/S) theory., PMID:38303079

Development of therapeutic monoclonal antibodies against DKK1 peptide-HLA-A2 complex to treat human cancers., PMID:38267222

Antibody verification of HLA class I and class II eplets by human monoclonal HLA antibodies., PMID:38239050

A dual-receptor T-cell platform with Ab-TCR and costimulatory receptor achieves specificity and potency against AML., PMID:38048594

Comparative analysis of Basiliximab and Alemtuzumab induction therapies in blood type A2-to-B kidney transplantation: Impact on kidney function and de novo donor-specific HLA antibodies., PMID:37949378

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