Catalog No.
PMK99001
Species reactivity
Mouse
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Mouse Reg3b (Gly43-Gly175).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Regenerating islet-derived protein 3-beta (REG-3-beta) (Pancreatitis-associated protein 1) (Regenerating islet-derived protein III-beta) (Reg III-beta) [Cleaved into: Regenerating islet-derived protein 3-beta 16.5 kDa form, Regenerating islet-derived protein 3-beta 15 kDa form]
Purification
Purified by antigen affinity column.
Accession
P35230
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Nerve Injury-Induced Neuronal PAP-I Maintains Neuropathic Pain by Activating Spinal Microglia., PMID:31744864
Dimorphic autoantigenic and protective effects of Reg2 peptide in the treatment of diabetic β-cell loss., PMID:30690849
Epithelial IL-23R Signaling Licenses Protective IL-22 Responses in Intestinal Inflammation., PMID:27524624
IL-22-induced antimicrobial peptides are key determinants of mucosal vaccine-induced protection against H. pylori in mice., PMID:27143303
IL17 Functions through the Novel REG3β-JAK2-STAT3 Inflammatory Pathway to Promote the Transition from Chronic Pancreatitis to Pancreatic Cancer., PMID:26404002
Deletion of intestinal epithelial cell STAT3 promotes T-lymphocyte STAT3 activation and chronic colitis following acute dextran sodium sulfate injury in mice., PMID:23429443
N-terminal cleaved pancreatitis-associated protein-III (PAP-III) serves as a scaffold for neurites and promotes neurite outgrowth., PMID:23426365
Xenograft of microencapsulated sertoli cells reverses T1DM in NOD mice by inducing neogenesis of beta-cells., PMID:21197711
Selective effect of INGAP-PP upon mouse embryonic stem cell differentiation toward islet cells., PMID:19159649
Microarray analysis of somatostatin receptor 5-regulated gene expression profiles in murine pancreas., PMID:19137362
Sumoylation regulates multiple aspects of mammalian poly(A) polymerase function., PMID:18281463
Pancreatic islet immunoreactivity to the Reg protein INGAP., PMID:17998566
Reg-II is an exocrine pancreas injury-response product that is up-regulated by keratin absence or mutation., PMID:17898082
Reg2 inactivation increases sensitivity to Fas hepatotoxicity and delays liver regeneration post-hepatectomy in mice., PMID:17133485
Expression of Reg/PAP family members during motor nerve regeneration in rat., PMID:15896308
p8 improves pancreatic response to acute pancreatitis by enhancing the expression of the anti-inflammatory protein pancreatitis-associated protein I., PMID:14660681
The pancreatitis-associated protein induces lung inflammation in the rat through activation of TNFalpha expression in hepatocytes., PMID:12579542
Localization of rat pancreatitis-associated protein during bile salt-induced pancreatitis., PMID:9024308
HIP/PAP is an adhesive protein expressed in hepatocarcinoma, normal Paneth, and pancreatic cells., PMID:8997243
Identification of a second rat pancreatitis-associated protein. Messenger RNA cloning, gene structure, and expression during acute pancreatitis., PMID:8369291
Human pancreatitis-associated protein. Messenger RNA cloning and expression in pancreatic diseases., PMID:1469087
A novel exocrine protein associated with pancreas transplantation in humans., PMID:1612332
For research use only. Not for human or drug use.
