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Anti-GP2 Polyclonal Antibody

Catalog #:   PHF11201 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P55259
Overview

Catalog No.

PHF11201

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human GP2 (Phe307-Asn512).

Tested applications

ELISA: 1:2000-1:8000, IHC: 1:50-1:100, WB: 1:500-1:4000

Target

Pancreatic zymogen granule membrane protein GP-2,GP2,ZAP75,Pancreatic secretory granule membrane major glycoprotein GP2

Concentration

1.49 mg/ml

Purification

Purified by antigen affinity column.

Accession

P55259

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with GP2 antibody (PHF11201) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 25 kDa
    Observed MW: 25 kDa
  • Western Blot
    Various lysates were subjected to SDS PAGE followed by western blot with GP2 antibody (PHF11201) at 1 μg/ml.

    Lane 1: Human muscle cell

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 57 kDa
    Observed MW: 57 kDa
  • Immunohistochemical
    Immunohistochemical analysis of human pancreas stained for GP2 with PHF11201.
References

Structure and stabilization of the antigenic glycoprotein building blocks of the New World mammarenavirus spike complex., PMID:40511941

Potent neutralization of Marburg virus by a vaccine-elicited monoclonal antibody., PMID:40463027

Ten years after introduction of NADC30-like strain in China: a novel chimeric porcine reproductive and respiratory syndrome vaccine candidate., PMID:40406142

Remdesivir, mAb114, REGN-EB3, and ZMapp partially rescue nonhuman primates infected with a low passage Kikwit variant of Ebola virus., PMID:40268932

Novel Insights Into Telocyte Presence and Distribution in the Cornea of the Laughing Dove (Spilopelia senegalensis) Using Immunofluorescence Analysis., PMID:40033837

Expression of Glycoprotein 2 and Its Glycosylation in Human Cowper's Gland., PMID:40026103

Repeat offenders: PRRSV-2 clinical re-breaks from a whole genome perspective., PMID:39919499

Peptide fibrils as a vaccine: Proof of concept., PMID:39832622

African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1., PMID:39802803

Discovery of Nanosota-EB1 and -EB2 as Novel Nanobody Inhibitors Against Ebola Virus Infection., PMID:39715280

African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1., PMID:39668204

A pan-orthoebolavirus neutralizing antibody encoded by mRNA effectively prevents virus infection., PMID:39560055

Novel Insights Into the Ultrastructural and Immunofluorescence Characteristics of Limb Skin in the Red-Eared Slider Turtle (Trachemys scripta elegans)., PMID:39508632

NK Cell-Based Cancer Immunotherapies: Current Progress, Challenges and Emerging Opportunities., PMID:39503181

Linear epitopes of PRRSV-1 envelope proteins ectodomains are not correlated with broad neutralization., PMID:39434120

A zebrafish gene with sequence similarities to human uromodulin and GP2 displays extensive evolutionary diversification among teleost and confers resistance to bacterial infection., PMID:39309883

Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design., PMID:39285186

Development of a live attenuated vaccine candidate for equid alphaherpesvirus 1 control: a step towards efficient protection., PMID:39021566

A broadly-neutralizing antibody against Ebolavirus glycoprotein that potentiates the breadth and neutralization potency of other antibodies., PMID:38979279

Glycoprotein-Specific Polyclonal Antibodies Targeting Machupo Virus Protect Guinea Pigs against Lethal Infection., PMID:38932403

Loss of mucosal tolerance to glycoprotein 2 isoform 1 is a potential novel diagnostic biomarker for cholangiocarcinoma., PMID:38853092

Macaque antibodies targeting Marburg virus glycoprotein induced by multivalent immunization., PMID:38832790

Selection of viral variants with enhanced transmission and reduced neutralization susceptibility alongside lateral introductions may explain the persistence of porcine reproductive and respiratory syndrome virus in vaccinated breeding herds., PMID:38817667

Advancements in dementia research, diagnostics, and care in Latin America: Highlights from the 2023 Alzheimer's Association International conference satellite symposium in Mexico City., PMID:38801124

Engineering and characterizing porcine reproductive and respiratory syndrome virus with separated and tagged genes encoding the minor glycoproteins., PMID:38795404

The Causality between Human Immunoglobulin G (IgG) N-Glycosylation and Aging: A Mendelian Randomization Study., PMID:38542917

Therapeutic potential of tocotrienols as chemosensitizers in cancer therapy., PMID:38353331

Candidate Biomarkers for Targeting in Type 1 Diabetes; A Bioinformatic Analysis of Pancreatic Cell Surface Antigens., PMID:38351729

Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability., PMID:38177144

Glycoprotein 2 as a gut gate keeper for mucosal equilibrium between inflammation and immunity., PMID:38170255

Development of Polycistronic Baculovirus Surface Display Vectors to Simultaneously Express Viral Proteins of Porcine Reproductive and Respiratory Syndrome and Analysis of Their Immunogenicity in Swine., PMID:38005998

Structural and molecular biology of Sabiá virus., PMID:37937408

Association between immunoglobulin G N-glycosylation and lupus nephritis in female patients with systemic lupus erythematosus: a case-control study., PMID:37809087

Application of spatial transcriptomics analysis using the Visium system for the mouse nasal cavity after intranasal vaccination., PMID:37545501

Structurally Different Yet Functionally Similar: Aptamers Specific for the Ebola Virus Soluble Glycoprotein and GP1,2 and Their Application in Electrochemical Sensing., PMID:36902059

Novel Insights Into Immunohistochemical Analysis For Acinar Cell Neoplasm of The Pancreas: Carboxypeptidase A2, Carboxypeptidase A1, and Glycoprotein 2., PMID:36815573

A high-throughput single-particle imaging platform for antibody characterization and a novel competition assay for therapeutic antibodies., PMID:36609657

Human glycoprotein-2 expressed in Brunner glands - A putative autoimmune target and link between Crohn's and coeliac disease., PMID:36608744

A Single Amino Acid Substitution in Porcine Reproductive and Respiratory Syndrome Virus Glycoprotein 2 Significantly Impairs Its Infectivity in Macrophages., PMID:36560826

Diagnostic and prognostic role of pancreatic secretory granule membrane major glycoprotein 2 (GP2) immunohistochemistry: A TMA study on 27,681 tumors., PMID:36137400

Identification of CD163 regions that are required for porcine reproductive and respiratory syndrome virus (PRRSV) infection but not for binding to viral envelope glycoproteins., PMID:35933832

Serological biomarkers for management of primary sclerosing cholangitis., PMID:35800183

Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies., PMID:35613585

Characterization of M Cells in Tear Duct-Associated Lymphoid Tissue of Mice: A Potential Role in Immunosurveillance on the Ocular Surface., PMID:34880872

HER2/neu-Based Peptide Vaccination-Pulsed with B-Cell Epitope Induced Efficient Prophylactic and Therapeutic Antitumor Activities in TUBO Breast Cancer Mice Model., PMID:34638441

Identification and Characterization of a Novel Single Domain Antibody Against Ebola Virus., PMID:34632543

Antibody-Based Inhibition of Pathogenic New World Hemorrhagic Fever Mammarenaviruses by Steric Occlusion of the Human Transferrin Receptor 1 Apical Domain., PMID:34132574

Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs., PMID:33952638

Impact of Coinfection with Schistosoma mansoni on the Antibody Response to Helicobacter pylori., PMID:33598776

Pancreatic glycoprotein 2 is a first line of defense for mucosal protection in intestinal inflammation., PMID:33594081

Datasheet

Document Download

Anti-GP2 Polyclonal Antibody.pdf

 

$ 170
Product specifications
50 μg 170 100 μg 280

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Anti-GP2 Polyclonal Antibody [PHF11201]
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