Catalog No.
PHF04001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PRKAA2 (Met1-Arg552).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PRKAA2,Acetyl-CoA carboxylase kinase,AMPK subunit alpha-2,ACACA kinase,AMPK,AMPK2,Hydroxymethylglutaryl-CoA reductase kinase,5'-AMP-activated protein kinase catalytic subunit alpha-2,HMGCR kinase
Purification
Purified by antigen affinity column.
Accession
P54646
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
4D label-free quantitative proteomic and phosphoproteomic profiling of the kidney in rat models of antimyeloperoxidase-associated vasculitis., PMID:40201969
Exploration and Identification of Vitamin D and Related Genes as Potential Biomarkers for Colorectal Tumors., PMID:39872437
AMPKα2 promotes tumor immune escape by inducing CD8+ T-cell exhaustion and CD4+ Treg cell formation in liver hepatocellular carcinoma., PMID:38424484
Comparison of CRISPR Genomic Tagging for Affinity Purification and Endogenous Immunoprecipitation Coupled with Quantitative Mass Spectrometry To Identify the Dynamic AMPKα2 Interactome., PMID:31398040
Autoantibody against β1-adrenoceptor promotes the differentiation of natural regulatory T cells from activated CD4+ T cells by up-regulating AMPK-mediated fatty acid oxidation., PMID:30770790
CaMKKβ-AMPKα2 signaling contributes to mitotic Golgi fragmentation and the G2/M transition in mammalian cells., PMID:25590814
AMPK/TSC2/mTOR-signaling intermediates are not necessary for LKB1-mediated nuclear retention of PTEN tumor suppressor., PMID:21123367
Ablation of AMP-activated protein kinase alpha1 and alpha2 from mouse pancreatic beta cells and RIP2.Cre neurons suppresses insulin release in vivo., PMID:20221584
Activation of AMP-activated protein kinase by vascular endothelial growth factor mediates endothelial angiogenesis independently of nitric-oxide synthase., PMID:20129920
Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle., PMID:19923418
Detection of AMP-activated protein kinase in human sera by immuno-isoelectric focusing., PMID:19818790
Long-term moderate ethanol consumption restores insulin sensitivity in high-fat-fed rats by increasing SLC2A4 (GLUT4) in the adipose tissue by AMP-activated protein kinase activation., PMID:18719073
Expression profiling of the gamma-subunit isoforms of AMP-activated protein kinase suggests a major role for gamma3 in white skeletal muscle., PMID:14559719
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise., PMID:12527721