Catalog No.
PHK20401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human SETD7 (Met1-Lys366).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Lysine N-methyltransferase 7, SET9, SET7/9, Histone H3-K4 methyltransferase SETD7, SET7, SET domain-containing protein 7, SETD7, H3-K4-HMTase SETD7, KIAA1717, Histone-lysine N-methyltransferase SETD7, KMT7
Purification
Purified by antigen affinity column.
Accession
Q8WTS6
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Methylation of the JMJD2B epigenetic regulator differentially affects its ability to coactivate the ETV1 and JUN transcription factors., PMID:38213775
Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumors., PMID:37055532
SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer's disease., PMID:34215303
Identification of Rpl29 as a major substrate of the lysine methyltransferase Set7/9., PMID:29959229
The HIV-1 Tat Protein Is Monomethylated at Lysine 71 by the Lysine Methyltransferase KMT7., PMID:27235396
A New Versatile Immobilization Tag Based on the Ultra High Affinity and Reversibility of the Calmodulin-Calmodulin Binding Peptide Interaction., PMID:26159704
Inhibition of SET Domain-Containing Lysine Methyltransferase 7/9 Ameliorates Renal Fibrosis., PMID:26045091
Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development., PMID:24619213
Methylation of SUV39H1 by SET7/9 results in heterochromatin relaxation and genome instability., PMID:23509280
Methylation by Set9 modulates FoxO3 stability and transcriptional activity., PMID:22820736
Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes., PMID:22345554
Development and validation of a generic fluorescent methyltransferase activity assay based on the transcreener AMP/GMP assay., PMID:21956169
Development of homogeneous nonradioactive methyltransferase and demethylase assays targeting histone H3 lysine 4., PMID:21940714
Lysine methylation and functional modulation of androgen receptor by Set9 methyltransferase., PMID:21273441
Multiple lysine methylation of PCAF by Set9 methyltransferase., PMID:19351588
For research use only. Not for human or drug use.
