Catalog No.
PHE92801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human STAT2 (Glu616-Ser849).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
p113,STAT2,Signal transducer and activator of transcription 2
Purification
Purified by antigen affinity column.
Accession
P52630
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Borrelia burgdorferi sensu lato inhibits CIITA transcription through pSTAT3 activation and enhanced SOCS1 and SOCS3 expression leading to limited IFN-γ production., PMID:39879745
Blood transcriptome profiling reveals distinct gene networks induced by mRNA vaccination against COVID-19., PMID:39402787
STAT4 and STAT6, their role in cellular and humoral immunity and in diverse human diseases., PMID:39188021
FXa-mediated PAR-2 promotes the efficacy of immunotherapy for hepatocellular carcinoma through immune escape and anoikis resistance by inducing PD-L1 transcription., PMID:39060025
Elevated unphosphorylated STAT1 and IRF9 in T and B cells of primary sjögren's syndrome: Novel biomarkers for disease activity and subsets., PMID:38788537
The Susceptibility of Chickens to Zika Virus: A Comprehensive Study on Age-Dependent Infection Dynamics and Host Responses., PMID:38675911
Zika purified inactivated virus (ZPIV) vaccine reduced vertical transmission in pregnant immunocompetent mice., PMID:38360793
Immunocompetent mouse models revealed that S100A4+ monocytes/macrophages facilitate long-term Zika virus infection in the testes., PMID:38164719
ISGF3 and STAT2/IRF9 Control Basal and IFN-Induced Transcription through Genome-Wide Binding of Phosphorylated and Unphosphorylated Complexes to Common ISRE-Containing ISGs., PMID:38139463
The NSs protein of severe fever with thrombocytopenia syndrome virus differentially inhibits the type 1 interferon response among animal species., PMID:37187292
Inborn Error of STAT2-Dependent IFN-I Immunity in a Patient Presented with Hemophagocytic Lymphohistiocytosis and Multisystem Inflammatory Syndrome in Children., PMID:37074537
Type I Interferonopathy due to a Homozygous Loss-of-Inhibitory Function Mutation in STAT2., PMID:36753016
Maternal antibodies induced by a live attenuated vaccine protect neonatal mice from cytomegalovirus., PMID:36737485
Integrated analysis identifies the IL6/JAK/STAT signaling pathway and the estrogen response pathway associated with the pathogenesis of intracranial aneurysms., PMID:36451838
Phase II clinical and immune correlate study of adjuvant nivolumab plus ipilimumab for high-risk resected melanoma., PMID:36450385
Genetic Diagnosis of Inborn Errors of Immunity in an Emerging Country: a Retrospective Study of 216 Moroccan Patients., PMID:36367635
Serum neurofilament light and MRI predictors of cognitive decline in patients with secondary progressive multiple sclerosis: Analysis from the MS-STAT randomised controlled trial., PMID:35946107
A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients., PMID:35842705
Transcription Factors and Regulators Pathway-focused Genes Expression Analysis in Patients with Different Forms of Thyroid Pathology., PMID:35176984
HHLA2 Activates the JAK/STAT Signaling Pathway by Binding to TMIGD2 in Hepatocellular Carcinoma Cells., PMID:35175496
Abnormalities of the type I interferon signaling pathway in lupus autoimmunity., PMID:34340046
Evaluating the Safety of West Nile Virus Immunity During Congenital Zika Virus Infection in Mice., PMID:34220838
The protein landscape of chronic lymphocytic leukemia., PMID:34189564
Impact of prior Dengue immunity on Zika vaccine protection in rhesus macaques and mice., PMID:34170962
IFN-β, but not IFN-α, is Responsible for the Pro-Bacterial Effect of Type I Interferon., PMID:33984198
Downregulation of SHANK-associated RH domain-interacting protein elevates interleukin-33 expression by stimulating the Janus kinase 2/signal transducer and activator of transcription signalling pathway in HaCaT cells., PMID:33548083
Zika virus NS3 protease induces bone morphogenetic protein-dependent brain calcification in human fetuses., PMID:33510473
Targeted Stat2 deletion in conventional dendritic cells impairs CTL responses but does not affect antibody production., PMID:33457079
Activation of an Effective Immune Response after Yellow Fever Vaccination Is Associated with the Genetic Background and Early Response of IFN-γ and CLEC5A., PMID:33445752
Atractylodis macrocephalae polysaccharides protect against DSS-induced intestinal injury through a novel lncRNA ITSN1-OT1., PMID:33248053
Dengue and Zika virus infections are enhanced by live attenuated dengue vaccine but not by recombinant DSV4 vaccine candidate in mouse models., PMID:32949997
The Measles Virus V Protein Binding Site to STAT2 Overlaps That of IRF9., PMID:32581091
Sunflower seed oil combined with ginseng stem-leaf saponins as an adjuvant to enhance the immune response elicited by Newcastle disease vaccine in chickens., PMID:32571723
Stat2 loss disrupts damage signalling and is protective in acute pancreatitis., PMID:32506441
Cloning and Expression of the Tibetan Pig Interleukin-23 Gene and Its Promotion of Immunity of Pigs to PCV2 Vaccine., PMID:32466622
Zika virus envelope nanoparticle antibodies protect mice without risk of disease enhancement., PMID:32305868
Identification of molecules associated with response to abatacept in patients with rheumatoid arthritis., PMID:32164778
Monoclonal Antibodies with Neutralizing Activity and Fc-Effector Functions against the Machupo Virus Glycoprotein., PMID:31801871
Influence of elevated protein and tannin-rich peanut skin supplementation on growth performance, blood metabolites, carcass traits and immune-related gene expression of grazing meat goats., PMID:31724236
Protective Efficacy of Nucleic Acid Vaccines Against Transmission of Zika Virus During Pregnancy in Mice., PMID:31260518
Antibodies Elicited by an NS1-Based Vaccine Protect Mice against Zika Virus., PMID:30940710
Differential Innate Immune Responses Elicited by Nipah Virus and Cedar Virus Correlate with Disparate In Vivo Pathogenesis in Hamsters., PMID:30909389
Human Polyclonal Antibodies Produced from Transchromosomal Bovine Provides Prophylactic and Therapeutic Protections Against Zika Virus Infection in STAT2 KO Syrian Hamsters., PMID:30678320
Platelet factor 4 promotes rapid replication and propagation of Dengue and Japanese encephalitis viruses., PMID:30527622
Analysis of STAT1, STAT2 and STAT3 mRNA expression levels in the blood of patients with multiple sclerosis., PMID:30412483
Human antibodies targeting Zika virus NS1 provide protection against disease in a mouse model., PMID:30385750
PDL1 is expressed in the islets of people with type 1 diabetes and is up-regulated by interferons-α and-γ via IRF1 induction., PMID:30269996
An Immunocompetent Mouse Model of Zika Virus Infection., PMID:29746837
Transcription profiling of peripheral B cells in antibody-positive primary Sjögren's syndrome reveals upregulated expression of CX3CR1 and a type I and type II interferon signature., PMID:29655283
CRISPR/Cas9 knockout of USP18 enhances type I IFN responsiveness and restricts HIV-1 infection in macrophages., PMID:29437254
For research use only. Not for human or drug use.
