Catalog No.
PHE15501
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GLRX (Met1-Gln106).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
TTase-1, GLRX, GRX, Thioltransferase-1, Glutaredoxin-1
Purification
Purified by antigen affinity column.
Accession
P35754
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Catalytic Cleavage of Disulfide Bonds in Small Molecules and Linkers of Antibody-Drug Conjugates., PMID:31085544
Glutaredoxin 1 (Grx1) Protects Human Retinal Pigment Epithelial Cells From Oxidative Damage by Preventing AKT Glutathionylation., PMID:25788646
Oxidative damage increases and antioxidant gene expression decreases with aging in the mouse ovary., PMID:21148108
Mitochondrial thioltransferase (glutaredoxin 2) has GSH-dependent and thioredoxin reductase-dependent peroxidase activities in vitro and in lens epithelial cells., PMID:17065220
Expression of glutaredoxin (thioltransferase) in the rat ovary during the oestrous cycle and postnatal development., PMID:15956334
Expression of glutaredoxin is highly cell specific in human lung and is decreased by transforming growth factor-beta in vitro and in interstitial lung diseases in vivo., PMID:15297967
Protein s-glutathionylation in retinal pigment epithelium converts heat shock protein 70 to an active chaperone., PMID:15109915
Cloning and expression of a novel human glutaredoxin (Grx2) with mitochondrial and nuclear isoforms., PMID:11297543
Nucleoredoxin, glutaredoxin, and thioredoxin differentially regulate NF-kappaB, AP-1, and CREB activation in HEK293 cells., PMID:10903915
Immunolocalization of glutaredoxin in the human corpus luteum., PMID:10508218
Characterization of mammalian thioredoxin reductase, thioredoxin and glutaredoxin by immunochemical methods., PMID:7749633
Immunolocalization of thioredoxin and glutaredoxin in mammalian hypophysis., PMID:1526311