Catalog No.
FHN05510
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
MUC-4, Ascites sialoglycoprotein 1, Ascites sialoglycoprotein 2, ASGP-1, ASGP-2, Testis mucin, MUC4, Ascites sialoglycoprotein, Pancreatic adenocarcinoma mucin, ASGP, Tracheobronchial mucin, Mucin-4
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q99102
Applications
ELISA, FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
8G7
Mucin 4 expression is associated with metastasis in triple-negative breast cancer and can be tackled by soluble TNF blockade, improving immunotherapy outcome., PMID:39987883
Decoding the Molecular Basis of the Specificity of an Anti-sTn Antibody., PMID:39886580
Amelioration of LPS-Induced Jejunum Injury and Mucus Barrier Damage in Mice by IgY Embedded in W/O/W Emulsion., PMID:39767078
Targeting Human Pancreatic Cancer with a Fluorophore-Conjugated Mucin 4 (MUC4) Antibody: Initial Characterization in Orthotopic Cell Line Mouse Models., PMID:39458160
Detection of MUC1+/MUC2 and MUC5AC- Membrane-Associated Mucins in the Intraepithelial Surface Mucous Cells of the Developing Rabbit Esophagus., PMID:39396509
Genome-wide association studies of COVID-19 vaccine seroconversion and breakthrough outcomes in UK Biobank., PMID:39384777
Morphological and functional features of the colonic mucus barrier in patients with symptomatic uncomplicated diverticular disease and acute uncomplicated diverticulitis., PMID:39241130
An extensive immunohistochemical analysis of 290 ovarian adult granulosa cell tumors with 29 markers., PMID:38904760
Diatomite-Based, Flexible SERS Immunosensor Platform for Rapid, Specific, and Sensitive Detection of Circulating Cancer-Specific Protein Biomarkers in Serum Using Raman Probes., PMID:38414330
The Expression of Mucin-4 (MUC4) in Sarcomas Apart From Sclerosing Epithelioid Fibrosarcoma and Low-Grade Fibromyxoid Sarcoma., PMID:38156143
Immunoexpression of HER2 pathway related markers in HER2 invasive breast carcinomas treated with trastuzumab., PMID:37977031
Blocking soluble TNFα sensitizes HER2-positive breast cancer to trastuzumab through MUC4 downregulation and subverts immunosuppression., PMID:36889811
Association of Sialyl Tn antigen with cervical cancer lymph node status: An NRG oncology/GOG study., PMID:36827840
[Alveolar rhabdomyosarcoma: novel surrogate markers associated with oncogenic translocation]., PMID:36785957
Whole-exome sequencing identifies a set of genes as markers of hepatocellular carcinoma early recurrence., PMID:36550350
Clinical Prognostic Factors and Integrated Multi-Omics Studies Identify Potential Novel Therapeutic Targets for Pediatric Desmoid Tumor., PMID:36539683
Low-grade fibromyxoid sarcoma in labial mucosa: Report of a rare case in a pediatric patient., PMID:36384080
HER2-targeted dual radiotracer approach with clinical potential for noninvasive imaging of trastuzumab-resistance caused by epitope masking., PMID:35910795
Anti-mucin 4 fluorescent antibody brightly targets colon cancer in patient-derived orthotopic xenograft mouse models: A proof-of-concept study for future clinical applications., PMID:35715267
Low-grade tracheal adenocarcinoma with ETV6::NTRK3 fusion: unique morphology akin to subsets of sinonasal low-grade non-intestinal-type adenocarcinoma., PMID:35670854
A Stable Gold Nanoparticle-Based Vaccine for the Targeted Delivery of Tumor-Associated Glycopeptide Antigens., PMID:34927166
Characterization of recombinant β subunit of human MUC4 mucin (rMUC4β)., PMID:34887447
Machine learning gene expression predicting model for ustekinumab response in patients with Crohn's disease., PMID:34469062
Integrative Analysis of MUC4 to Prognosis and Immune Infiltration in Pan-Cancer: Friend or Foe?, PMID:34336844
Diagnostic Immunohistochemistry of Soft Tissue and Bone Tumors: An Update on Biomarkers That Correlate with Molecular Alterations., PMID:33921435
Mucins as anti-cancer targets: perspectives of the glycobiologist., PMID:33704667
MUC4 enhances gemcitabine resistance and malignant behaviour in pancreatic cancer cells expressing cancer-associated short O-glycans., PMID:33485947
LPCAT2 Methylation, a Novel Biomarker for the Severity of Cedar Pollen Allergic Rhinitis in Japan., PMID:33356413
Membrane-bound mucins of the airway mucosal surfaces are densely decorated with keratan sulfate: revisiting their role in the Lung's innate defense., PMID:33083824
Targeting interleukin-17 receptor B enhances gemcitabine sensitivity through downregulation of mucins in pancreatic cancer., PMID:33082357
Polyanhydride nanoparticles stabilize pancreatic cancer antigen MUC4β., PMID:32776461
Early-life lactoferrin intervention modulates the colonic microbiota, colonic microbial metabolites and intestinal function in suckling piglets., PMID:32444999
Nanoparticles modified by triple single chain antibodies for MRI examination and targeted therapy in pancreatic cancer., PMID:32031201
Dietary supplementation with ovine serum immunoglobulin modulates correlations between mucin, microbiota and immunity proteins in the growing rat., PMID:31994255
MUCIN-4 (MUC4) is a novel tumor antigen in pancreatic cancer immunotherapy., PMID:31952903
The dichotomous role of epiregulin in pain., PMID:31917773
Amphiphilic polyanhydride-based recombinant MUC4β-nanovaccine activates dendritic cells., PMID:31258832
A Tumor-Selective Monoclonal Antibody from Immunization with a Tumor-Associated Mucin Glycopeptide., PMID:30952968
A New Ophthalmic Pharmaceutical Formulation, Topical Sulglycotide, Enhances the Ocular Mucin Secretion in Desiccation Stress-Mediated Dry Eye Disease., PMID:30901389
Irinotecan induces enterocyte cell death and changes to muc2 and muc4 composition during mucositis in a tumour-bearing DA rat model., PMID:30815720
EPHA5 mediates trastuzumab resistance in HER2-positive breast cancers through regulating cancer stem cell-like properties., PMID:30620624
Cancer-associated mucins: role in immune modulation and metastasis., PMID:30618016
Low-grade fibromyxoid sarcoma of the extremities: a clinicopathologic study of 24 cases and review of the literature., PMID:30509048
QSurface: fast identification of surface expression markers in cancers., PMID:29560830
Invasive micropapillary carcinoma of the breast overexpresses MUC4 and is associated with poor outcome to adjuvant trastuzumab in HER2-positive breast cancer., PMID:29281999
Development and In Vitro Characterization of a Gemcitabine-loaded MUC4-targeted Immunoliposome Against Pancreatic Ductal Adenocarcinoma., PMID:29061782
Expression of dog1 in low-grade fibromyxoid sarcoma: A study of 19 cases and review of the literature., PMID:28965630
Immunohistochemical expression profiles of mucin antigens in salivary gland mucoepidermoid carcinoma: MUC4- and MUC6-negative expression predicts a shortened survival in the early postoperative phase., PMID:28649694
Cultivation and characterization of pterygium as an ex vivo study model for disease and therapy., PMID:28550976
The content of mucin MUC-2, -3 and -4 antigens in the bronchial mucosa membrane of chronic obstructive pulmonary disease patients during acute exacerbation - initial report., PMID:28198987
For research use only. Not for human or drug use.
