Catalog No.
PHE70401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VEGFC (Glu47-Trp413).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Vascular endothelial growth factor C,VEGFC,Flt4-L,VEGF-C,Vascular endothelial growth factor-related protein,VRP,Flt4 ligand
Purification
Purified by antigen affinity column.
Accession
P49767
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Advances in Molecular Imaging of VEGFRs: Innovations in Imaging and Therapeutics., PMID:40508182
VEGF-C and Lymphatic Vessel Density in Tumor Tissue of Gastric Cancer: Correlations with Pathoclinical Features and Prognosis., PMID:40361332
A phase two trial evaluating FOLFIRI plus aflibercept after failure of FOLFOXIRI plus bevacizumab in patients with unresectable metastatic colorectal cancer., PMID:39891883
Decoding lymphangiogenesis in oral squamous cell carcinoma: Emphasis on clinical and histopathological determinants of regional metastasis., PMID:39541328
Immunotherapeutic Innovations in Clear Cell Renal Cell Carcinoma: Current Strategies and Future Directions., PMID:39238630
Efficacy of chemotherapy containing bevacizumab in patients with metastatic colorectal cancer according to programmed cell death ligand 1., PMID:39171162
Gene Therapy for Non-Hereditary Retinal Disease: Age-Related Macular Degeneration, Diabetic Retinopathy, and Beyond., PMID:38927656
The RANKL inhibitor denosumab in combination with dual checkpoint inhibition is associated with increased CXCL-13 serum concentrations., PMID:38479119
Analysis of Changes in Plasma Cytokine Levels in Response to IL12 Therapy in Three Clinical Trials., PMID:38108458
Treatment for Gorham-Stout syndrome with a combination of teriparatide and denosumab., PMID:38062162
Correction: Involvement of the VEGF receptor 3 in tubular morphogenesis demonstrated with a human antihuman VEGFR-3 monoclonal antibody that antagonizes receptor activation by VEGF-C., PMID:37675777
Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer., PMID:37134151
Promotion of Lymphangiogenesis by Targeted Delivery of VEGF-C Improves Diabetic Wound Healing., PMID:36766814
A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration., PMID:36754174
Antibody-Mediated Delivery of VEGF-C Promotes Long-Lasting Lymphatic Expansion That Reduces Recurrent Inflammation., PMID:36611965
Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401
Hypoxia-inducible factor pathway genes predict survival in metastatic clear cell renal cell carcinoma., PMID:35973929
Combination of sunitinib and 177Lu-labeled antibody cG250 targeted radioimmunotherapy: A promising new therapeutic strategy for patients with advanced renal cell cancer., PMID:35878454
Regulation and impact of cardiac lymphangiogenesis in pressure-overload-induced heart failure., PMID:35689481
VEGF-C serum level is associated with response to bevacizumab maintenance therapy in primary ovarian cancer patients., PMID:35687576
Periostin in lymph node pre-metastatic niches governs lymphatic endothelial cell functions and metastatic colonization., PMID:35567669
Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects., PMID:35434898
Drainage of senescent astrocytes from brain via meningeal lymphatic routes., PMID:35427759
HMGB1 Promotes Lymphangiogenesis through the Activation of RAGE on M2 Macrophages in Laryngeal Squamous Cell Carcinoma., PMID:35280439
Cabozantinib with or without Panitumumab for RAS wild-type metastatic colorectal cancer: impact of MET amplification on clinical outcomes and circulating biomarkers., PMID:35171350
Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-Based Regimens., PMID:34793664
Epstein-Barr Virus Induces Lymphangiogenesis and Lympth Node Metastasis via Upregulation of VEGF-C in Nasopharyngeal Carcinoma., PMID:34654722
VEGF-C/VEGFR-3 signalling in macrophages ameliorates acute lung injury., PMID:34446463
Immunohistochemical expression and prognostic significance of VEGF-C in well-differentiated thyroid cancer., PMID:34084231
Anti-Vascular Endothelial Growth Factor C Antibodies Efficiently Inhibit the Growth of Experimental Clear Cell Renal Cell Carcinomas., PMID:34067671
Expression levels of VEGF-C and VEGFR-3 in renal cell carcinoma and their association with lymph node metastasis., PMID:33850526
PCR Array Technology in Biopsy Samples Identifies Up-Regulated mTOR Pathway Genes as Potential Rejection Biomarkers After Kidney Transplantation., PMID:33681239
circEHBP1 promotes lymphangiogenesis and lymphatic metastasis of bladder cancer via miR-130a-3p/TGFβR1/VEGF-D signaling., PMID:33545359
IL-33 and Superantigenic Activation of Human Lung Mast Cells Induce the Release of Angiogenic and Lymphangiogenic Factors., PMID:33445787
Identifying Genetic Risk Factors for Diabetic Macular Edema and the Response to Treatment., PMID:33274237
Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions., PMID:33210556
Detecting cancer metastasis and accompanying protein biomarkers at single cell levels using a 3D-printed microfluidic immunoarray., PMID:33096435
Lymphatic Proliferation Ameliorates Pulmonary Fibrosis after Lung Injury., PMID:33039355
Myeloid-derived suppressor cells improve corneal graft survival through suppressing angiogenesis and lymphangiogenesis., PMID:32892499
Phase I and Biomarker Study of the Wnt Pathway Modulator DKN-01 in Combination with Gemcitabine/Cisplatin in Advanced Biliary Tract Cancer., PMID:32878766
Correlations of recurrence of gastric cancer in patients after radical surgery with serum gastrointestinal hormones, vascular endothelial growth factors and serum anti-helicobacter pylori IgG antibody., PMID:32862593
New insights into the role of co-receptor neuropilins in tumour angiogenesis and lymphangiogenesis and targeted therapy strategies., PMID:32838575
Distinct fibroblast subsets regulate lacteal integrity through YAP/TAZ-induced VEGF-C in intestinal villi., PMID:32796823
Phase Ib study of FOLFOXIRI plus ramucirumab as first-line treatment for patients with metastatic colorectal cancer., PMID:32710148
The immune-checkpoint HLA-G/ILT4 is involved in the regulation of VEGF expression in clear cell renal cell carcinoma., PMID:32620162
Lymphatic and Immune Cell Cross-Talk Regulates Cardiac Recovery After Experimental Myocardial Infarction., PMID:32404007
HIV gp120 Induces the Release of Proinflammatory, Angiogenic, and Lymphangiogenic Factors from Human Lung Mast Cells., PMID:32375243
Analyzing the factors that influence occult metastasis in oral tongue cancer., PMID:32364349
CCL25 promotes the migration and invasion of non-small cell lung cancer cells by regulating VEGF and MMPs in a CCR9-dependent manner., PMID:32346420
Antibody-Mediated Delivery of VEGFC Ameliorates Experimental Chronic Colitis., PMID:32259068
For research use only. Not for human or drug use.
