Catalog No.
PHE68801
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MCM2 (Phe657-Phe904).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CCNL1,KIAA0030,Minichromosome maintenance protein 2 homolog,Nuclear protein BM28,MCM2,CDCL1,BM28,DNA replication licensing factor MCM2
Purification
Purified by antigen affinity column.
Accession
P49736
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Investigating Anti-Tumor Effects of Irisin in Cervical Cancer Cells: Cell Viability, Migration, and Tumor-Associated Macrophage Polarization., PMID:40415369
Visualizing the dynamics of DNA replication and repair at the single-molecule level., PMID:38359974
Role of Serine arginine protein kinase 1 and Minichromosome maintenance protein 2 in predicting epithelial ovarian cancer response to treatment and prognosis., PMID:38216547
Histomorphological evaluation, cell proliferation and endothelial immunostaining in oral and maxillofacial myofibroblastic lesions., PMID:36243994
Solving the MCM paradox by visualizing the scaffold of CMG helicase at active replisomes., PMID:36241664
Identification of the ataxin-1 interaction network and its impact on spinocerebellar ataxia type 1., PMID:35906672
The Inducible Intein-Mediated Self-Cleaving Tag (IIST) System: A Novel Purification and Amidation System for Peptides and Proteins., PMID:34641492
RPL21 siRNA Blocks Proliferation in Pancreatic Cancer Cells by Inhibiting DNA Replication and Inducing G1 Arrest and Apoptosis., PMID:33014855
Predictive value of p16INK4a, Ki-67 and ProExC immuno-qualitative features in LSIL progression into HSIL., PMID:32256722
Diagnosis of urinary bladder urothelial carcinoma by immunocytology with p53, MCM5, MCM2 and Ki-67 antibodies using cell blocks derived from urine., PMID:30943322
Assessment of Proliferative Index Between the Tumor Margin, Center of Tumor, and the Invasive Tumor Front of Oral Squamous Cell Carcinoma With the Help of Mcm-2: An Immunohistochemical Study., PMID:30359334
Cells in the adult human spinal cord ependymal region do not proliferate after injury., PMID:30091291
Doublecortin-expressing cell types in temporal lobe epilepsy., PMID:30005693
MCM-2 expression differentiates potentially malignant verrucous lesions from oral carcinomas., PMID:29661732
Significance of DNA Replication Licensing Proteins (MCM2, MCM5 and CDC6), p16 and p63 as Markers of Premalignant Lesions of the Uterine Cervix: Its Usefulness to Predict Malignant Potential., PMID:29373905
Effect of daidzein and equol on DNA replication in MCF-7 cells., PMID:29346578
ProEx C as Diagnostic Marker for Detection of Urothelial Carcinoma in Urinary Samples: A Review., PMID:28638271
MCM2 expression in serrated polyps demonstrates aberrant cellular proliferation., PMID:28302537
GAK is phosphorylated by c-Src and translocated from the centrosome to chromatin at the end of telophase., PMID:28135906
DNA ploidy and cell cycle protein expression in oral squamous cell carcinomas with and without lymph node metastases., PMID:28135012
Characterization and clinical validation of MCM2 and TOP2A monoclonal antibodies in the BD ProEx™ C assay: An immunoassay which detects aberrant S-phase induction in cervical tissue., PMID:28093271
Knockdown of Minichromosome Maintenance Proteins Inhibits Foci Forming of Mediator of DNA-Damage Checkpoint 1 in Response to DNA Damage in Human Esophageal Squamous Cell Carcinoma TE-1 Cells., PMID:27908247
MCM - 2 and Ki - 67 as proliferation markers in renal cell carcinoma: A quantitative and semi - quantitative analysis., PMID:27532114
Diagnostic and Prognostic Value of ProEx C and GLUT1 in Melanocytic Lesions., PMID:27272799
The presence of extra chromosomes leads to genomic instability., PMID:26876972
Immunoexpression of Ki-67, MCM2, and MCM3 in Ameloblastoma and Ameloblastic Carcinoma and Their Correlations with Clinical and Histopathological Patterns., PMID:26823641
Prognostic significance of MCM 2 and Ki-67 in neuroblastic tumors in children., PMID:26671918
Assessment of cell proliferation in renal cell carcinoma using dual-phase 18F-fluorodeoxyglucose PET/CT., PMID:26622577
Targeting MCM2 function as a novel strategy for the treatment of highly malignant breast tumors., PMID:26430873
Long-Term Effects of Intracerebroventricular Streptozotocin Treatment on Adult Neurogenesis in the Rat Hippocampus., PMID:26159196
Comparison of the blood and lymphatic microvessel density of pleomorphic adenoma and Basal cell adenoma., PMID:25987856
Cell cycle and apoptosis regulatory proteins, proliferative markers, cell signaling molecules, CD209, and decorin immunoreactivity in low-grade myxofibrosarcoma and myxoma., PMID:25940995
Orc1 Binding to Mitotic Chromosomes Precedes Spatial Patterning during G1 Phase and Assembly of the Origin Recognition Complex in Human Cells., PMID:25784553
Dynamic loading and redistribution of the Mcm2-7 helicase complex through the cell cycle., PMID:25555795
Expression of ProEx C in primary and metastatic urothelial carcinoma., PMID:24975746
Imaging analysis to determine chromatin binding of the licensing factor MCM2-7 in mammalian cells., PMID:24906334
MCM2/TOP2A (ProExC) immunohistochemistry as a predictive marker in head and neck mucosal biopsies., PMID:24630889
Utility of ProEx C in the histologic evaluation of the neoplastic and nonneoplastic urothelial lesions., PMID:24029711
Cell lineage identification and stem cell culture in a porcine model for the study of intestinal epithelial regeneration., PMID:23840480
Markers of cell division cycle in glioblastoma: significance in prediction of treatment response and patient prognosis., PMID:23477614
ProEx C as an adjunct marker to improve cytological detection of urothelial carcinoma in urinary specimens., PMID:23364848
Protein interaction and cellular localization of human CDC45., PMID:23364835
Immunohistochemical features of multifocal melanoacanthoma in the hard palate: a case report., PMID:23356913
MCM2 expression levels predict diagnosis and prognosis in gastric cardiac cancer., PMID:23329420
Role of cell cycle biomarkers in human papillomavirus related uterine lesions., PMID:23016774
High-content imaging in cervical cancer screening., PMID:22972847
[Expression of ProEXC, p16 and Ki-67 in cervical intraepithelial lesion by immunohistochemistry: diagnostic and clinical significance]., PMID:22932410
Expression of minichromosome maintenance 2, Ki-67, and geminin in oral nevi and melanoma., PMID:22652151
Analysis of dynamic changes in the proteome of a Bcl-XL overexpressing Chinese hamster ovary cell culture during exponential and stationary phases., PMID:22556165
Tissue microarray technique in evaluation of proliferative activity in invasive ductal breast cancer., PMID:22399591
For research use only. Not for human or drug use.
