Catalog No.
RHD45201
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Target
ABP-280, Actin-binding protein 280, Non-muscle filamin, FLN, FLN1, Filamin-A, FLNA, Filamin-1, Endothelial actin-binding protein, Alpha-filamin, FLN-A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P21333
Applications
ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1932
PACSIN2 regulates platelet integrin β1 hemostatic function., PMID:37678551
Involvement of muscle satellite cell dysfunction in neuromuscular disorders: Expanding the portfolio of satellite cell-opathies., PMID:35302338
Filamin A and parafibromin expression in parathyroid carcinoma., PMID:34606470
The proteomes of endometrial stromal cell-derived extracellular vesicles following a decidualizing stimulus define the cells' potential for decidualization success., PMID:34524461
Modulation of Actin Filament Dynamics by Inward Rectifying of Potassium Channel Kir2.1., PMID:33050503
R5, a neutralizing antibody to Robo1, suppresses breast cancer growth and metastasis by inhibiting angiogenesis via down-regulating filamin A., PMID:31811830
Filamin A Modulates Store-Operated Ca2+ Entry by Regulating STIM1 (Stromal Interaction Molecule 1)-Orai1 Association in Human Platelets., PMID:29284605
Two rheumatoid arthritis-specific autoantigens correlate microbial immunity with autoimmune responses in joints., PMID:28650341
Fatty acid synthase inhibits the O-GlcNAcase during oxidative stress., PMID:28232487
Identification of novel autoantigens via mass spectroscopy-based antibody-mediated identification of autoantigens (MS-AMIDA) using immune thrombocytopenic purpura (ITP) as a model disease., PMID:28137667
Overexpression of filamin-A protein is associated with aggressive phenotype and poor survival outcomes in NSCLC patients treated with platinum-based combination chemotherapy., PMID:26774150
Exon skipping causes atypical phenotypes associated with a loss-of-function mutation in FLNA by restoring its protein function., PMID:26059841
Analysis of the androgen receptor/filamin a complex in stromal cells., PMID:25182765
Prolonged androgen deprivation leads to overexpression of calpain 2: implications for prostate cancer progression., PMID:24297527
Analysis of the local organization and dynamics of cellular actin networks., PMID:24081490
Structure and function of palladin's actin binding domain., PMID:23806659
Model of a six immunoglobulin-like domain fragment of filamin A (16-21) built using residual dipolar couplings., PMID:22452512
A meckelin-filamin A interaction mediates ciliogenesis., PMID:22121117
Differential mechanical stability of filamin A rod segments., PMID:21889461
Structure of filamin A immunoglobulin-like repeat 10 from Homo sapiens., PMID:21821884
Structural and functional evaluation of C. elegans filamins FLN-1 and FLN-2., PMID:21799850
A novel association between filamin A and NF-κB inducing kinase couples CD28 to inhibitor of NF-κB kinase α and NF-κB activation., PMID:21277899
Biochemical basis of the interaction between cystic fibrosis transmembrane conductance regulator and immunoglobulin-like repeats of filamin., PMID:20351101
Cystic fibrosis transmembrane conductance regulator interacts with multiple immunoglobulin domains of filamin A., PMID:20351098
Identification of Filamin A as a BRCA1-interacting protein required for efficient DNA repair., PMID:20305393
Filamin B plays a key role in vascular endothelial growth factor-induced endothelial cell motility through its interaction with Rac-1 and Vav-2., PMID:20110358
Filamins regulate cell spreading and initiation of cell migration., PMID:19915675
1H, 13C and 15N resonance assignments of the human filamin A tandem immunoglobulin-like domains 16-17 and 18-19., PMID:19636946
MEKK4 signaling regulates filamin expression and neuronal migration., PMID:17145501
Chicken gizzard filamin, retina filamin and cgABP260 are respectively, smooth muscle-, non-muscle- and pan-muscle-type isoforms: distribution and localization in muscles., PMID:15986405
Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL., PMID:15461588
Filamin A, the Arp2/3 complex, and the morphology and function of cortical actin filaments in human melanoma cells., PMID:11706047
Dopamine D2 and D3 receptors are linked to the actin cytoskeleton via interaction with filamin A., PMID:11320256
Characterization of muscle filamin isoforms suggests a possible role of gamma-filamin/ABP-L in sarcomeric Z-disc formation., PMID:10658210
Expression and subcellular distribution of filamin isotypes in endothelial cells and pericytes., PMID:9548299
For research use only. Not for human or drug use.
