Anti-ABCG1 Polyclonal Antibody

Catalog No.

PHE45201

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ABCG1 (Met1-His353).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

ATP-binding cassette transporter 8,ABC8,ATP-binding cassette sub-family G member 1,ABCG1,WHT1,White protein homolog

Purification

Purified by antigen affinity column.

Accession

P45844

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Effects of micro- and nanoplastic exposure on macrophages: a review of molecular and cellular mechanisms., PMID:40323219

Structural bioinformatics studies of six human ABC transporters and their AlphaFold2-predicted water-soluble QTY variants., PMID:38577032

Soluble CD83 modulates human-monocyte-derived macrophages toward alternative phenotype, function, and metabolism., PMID:38162675

Transcription factor FfmA interacts both physically and genetically with AtrR to properly regulate gene expression in the fungus Aspergillus fumigatus., PMID:37333080

Cholesterol accumulation in macrophages drives NETosis in atherosclerotic plaques via IL-1β secretion., PMID:36537208

Application of Micro-Western Array for Identifying Different Serum Protein Expression Profile among Healthy Control, Alzheimer's Disease Patients and Patients' Adult Children., PMID:36138870

PPARγ Ameliorates Mycobacterium tuberculosis H37Ra-Induced Foamy Macrophage Formation via the ABCG1-Dependent Cholesterol Efflux Pathway in THP-1 Macrophages., PMID:35432274

A Combined Bioinformatic and Nanoparticle-Based Study Reveal the Role of ABCG2 in the Drug Resistant Breast Cancer., PMID:33602075

Clematichinenoside AR Alleviates Foam Cell Formation and the Inflammatory Response in Ox-LDL-Induced RAW264.7 Cells by Activating Autophagy., PMID:33151398

Dual role of phosphatidylserine and its receptors in osteoclastogenesis., PMID:32612123

Inhibition of USP14 suppresses the formation of foam cell by promoting CD36 degradation., PMID:31970862

Effects of β2/aβ2 on oxLDL-induced CD36 activation in THP-1 macrophages., PMID:31654747

Relationship between HDL Cholesterol Efflux Capacity, Calcium Coronary Artery Content, and Antibodies against ApolipoproteinA-1 in Obese and Healthy Subjects., PMID:31443207

Atorvastatin Blocks Advanced Glycation End Products Induced Reduction in Macrophage Cholesterol Efflux Mediated With ATP-Binding Cassette Transporters G 1., PMID:31378770

CCN family member 1 deregulates cholesterol metabolism and aggravates atherosclerosis., PMID:30347516

Pro-opiomelanocortin and its Processing Enzymes Associate with Plaque Stability in Human Atherosclerosis - Tampere Vascular Study., PMID:30305673

Regulation of Human γδ T Cells by BTN3A1 Protein Stability and ATP-Binding Cassette Transporters., PMID:29670629

ABCG1 regulates pulmonary surfactant metabolism in mice and men., PMID:28264879

Contributions of both ATP-Binding Cassette Transporter and Cyp51A Proteins Are Essential for Azole Resistance in Aspergillus fumigatus., PMID:28264842

Inhibitory effect of PCSK9 on Abca1 protein expression and cholesterol efflux in macrophages., PMID:27940374

Advanced glycation end products increase lipids accumulation in macrophages through upregulation of receptor of advanced glycation end products: increasing uptake, esterification and decreasing efflux of cholesterol., PMID:27644038

Characterization of native PfABCG protein in Plasmodium falciparum., PMID:26239803

ABCA1 contributes to macrophage deposition of extracellular cholesterol., PMID:26203076

β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages., PMID:26101463

ABCG1 is required for pulmonary B-1 B cell and natural antibody homeostasis., PMID:25339664

Infliximab reverses suppression of cholesterol efflux proteins by TNF-α: a possible mechanism for modulation of atherogenesis., PMID:24587984

Activation of soluble guanylyl cyclase prevents foam cell formation and atherosclerosis., PMID:24299003

ABCG1-mediated generation of extracellular cholesterol microdomains., PMID:24212237

Novel effect of paeonol on the formation of foam cells: promotion of LXRα-ABCA1-dependent cholesterol efflux in macrophages., PMID:24117070

Pharmacogenomics variation in drug metabolizing enzymes and transporters in relation to docetaxel toxicity in Lebanese breast cancer patients: paving the way for OMICs in low and middle income countries., PMID:23758476

Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus., PMID:23562986

Ligation of RAGE with ligand S100B attenuates ABCA1 expression in monocytes., PMID:23523156

DNA topoisomerase II inhibitors induce macrophage ABCA1 expression and cholesterol efflux-an LXR-dependent mechanism., PMID:23466610

Characterization of palmitoylation of ATP binding cassette transporter G1: effect on protein trafficking and function., PMID:23388354

ATPase activity of human ABCG1 is stimulated by cholesterol and sphingomyelin., PMID:23172659

Dietary β-carotene regulates interleukin-1β-induced expression of apolipoprotein E in astrocytes isolated from stroke-prone spontaneously hypertensive rats., PMID:23147682

ATP-binding cassette transporter G1 intrinsically regulates invariant NKT cell development., PMID:23100511

Specific Kv1.3 blockade modulates key cholesterol-metabolism-associated molecules in human macrophages exposed to ox-LDL., PMID:23099443

Rituximab therapy in pulmonary alveolar proteinosis improves alveolar macrophage lipid homeostasis., PMID:22697800

Associations of ATP-binding cassette transporter A1 and G1 with insulin secretion in human insulinomas., PMID:22466164

ABCA17 mediates sterol efflux from mouse spermatozoa plasma membranes., PMID:22237709

Lentivirus-ABCG1 instillation reduces lipid accumulation and improves lung compliance in GM-CSF knock-out mice., PMID:22033401

Rosuvastatin blocks advanced glycation end products-elicited reduction of macrophage cholesterol efflux by suppressing NADPH oxidase activity via inhibition of geranylgeranylation of Rac-1., PMID:21823057

Wogonin promotes cholesterol efflux by increasing protein phosphatase 2B-dependent dephosphorylation at ATP-binding cassette transporter-A1 in macrophages., PMID:21190831

Involvement of low-density lipoprotein receptor-related protein and ABCG1 in stimulation of axonal extension by apoE-containing lipoproteins., PMID:21040802

Placental ABCA1 and ABCG1 transporters efflux cholesterol and protect trophoblasts from oxysterol induced toxicity., PMID:20570635

Anti-atherogenic effect of berberine on LXRalpha-ABCA1-dependent cholesterol efflux in macrophages., PMID:20506155

Tryptase promotes human monocyte-derived macrophage foam cell formation by suppressing LXRalpha activation., PMID:20139031

Targeted PPAR{gamma} deficiency in alveolar macrophages disrupts surfactant catabolism., PMID:20064973

Stimulation of cholesterol efflux by LXR agonists in cholesterol-loaded human macrophages is ABCA1-dependent but ABCG1-independent., PMID:19729607

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