Catalog No.
PHE45101
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MMP13 (Leu20-Cys471).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
MMP-13,MMP13,Matrix metalloproteinase-13,Collagenase 3
Purification
Purified by antigen affinity column.
Accession
P45452
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Carpaine ameliorates synovial inflammation by promoting p65 degradation and inhibiting the NF-κB signalling pathway., PMID:40237708
Nanocellulose-modified electrodes for simultaneous biosensing of microbiome-related oral diseases biomarkers., PMID:39932508
Bifidobacterium animalis BD400 protects from collagen-induced arthritis through histidine metabolism., PMID:39911381
Protective effect of a combination of multiple strains of Lactobacillus acidophilus on collagen-induced arthritis., PMID:39807088
Celecoxib Combined with Tocilizumab Has Anti-Inflammatory Effects and Promotes the Recovery of Damaged Cartilage via the Nrf2/HO-1 Pathway In Vitro., PMID:39766343
Exploring Intra-Articular Administration of Monoclonal Antibodies as a Novel Approach to Osteoarthritis Treatment: A Systematic Review., PMID:39457530
Mapping RANKL- and OPG-expressing cells in bone tissue: the bone surface cells as activators of osteoclastogenesis and promoters of the denosumab rebound effect., PMID:39424806
The novel HSP90 monoclonal antibody 9B8 ameliorates articular cartilage degeneration by inhibiting glycolysis via the HIF-1 signaling pathway., PMID:39229534
Syndecan-4 inhibition attenuates cartilage degeneration in temporomandibular joint osteoarthritis., PMID:39101668
Lysosomal degradation of PD-L1 is associated with immune-related adverse events during anti-PD-L1 immunotherapy in NSCLC patients., PMID:38799168
Combinatory Nanovesicle with siRNA-Loaded Extracellular Vesicle and IGF-1 for Osteoarthritis Treatments., PMID:38791285
Evaluation of MMP-9, MMP-13, MMP-21, and TIMP-1 expressions in malign melanom, dysplastic nevi, and banal nevi., PMID:38757103
Protein kinase D drives the secretion of invasion mediators in triple-negative breast cancer cell lines., PMID:38323010
Macrophage expressed tartrate-resistant acid phosphatase 5 promotes pulmonary fibrosis progression., PMID:38178705
The role of EDIL3 in maintaining cartilage extracellular matrix and inhibiting osteoarthritis development., PMID:38081212
Anti-Inflammatory Effects of Boric Acid in Treating Knee Osteoarthritis: Biochemical and Histopathological Evaluation in Rat Model., PMID:37770671
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-κB and MAPK signaling pathways., PMID:37586160
Angiopoietin-2 Promotes Mechanical Stress-induced Extracellular Matrix Degradation in Annulus Fibrosus Via the HIF-1α/NF-κB Signaling Pathway., PMID:37475697
Histopathological, biochemical and molecular studies on a model of systemic autoimmune disease induced by sodium silicate in non-genetically prone rats., PMID:37100362
MMP2 is a immunotherapy related biomarker and correlated with cancer-associated fibroblasts infiltrate in melanoma., PMID:36788565
Bevacizumab suppressed degenerative changes in articular cartilage explants from patients with osteoarthritis of the knee., PMID:36627659
Immune function modulation during artificial ovarian maturation in Japanese eel (Anguilla japonica): A transcriptome profiling approach., PMID:36341870
Tofacitinib Inhibits STAT Phosphorylation and Matrix Metalloproteinase-3, -9 and -13 Production by C28/I2 Human Juvenile Chondrocytes., PMID:36217356
Interleukin-6 neutralization and regulatory T cells are additive in chondroprotection from IL-1β-induced inflammation., PMID:36205183
IL-1 receptor antagonist (IL-1RA) suppresses a hyper-IL-17 response-mediated bone loss in a murine experimental periodontitis., PMID:36191445
Atorvastatin attenuates NS1 (Non-structural protein-1) of dengue type-2 serotype-induced expressions of matrix metalloproteinases in HL-60 cells, differentiated to neutrophils: Implications for the immunopathogenesis of dengue viral disease., PMID:36108401
Inhibition of HMGB1 suppresses inflammation and catabolism in temporomandibular joint osteoarthritis <em>via</em> NF-κB signaling pathway., PMID:35726537
Autologous hematopoietic stem cell transplantation promotes connective tissue remodeling in systemic sclerosis patients., PMID:35488348
Release of Matrix Metalloproteinases by Macrophages in Radicular Cysts and Residual Radicular Cysts., PMID:35384879
Mechanical Stimulation Protects Against Chondrocyte Pyroptosis Through Irisin-Induced Suppression of PI3K/Akt/NF-κB Signal Pathway in Osteoarthritis., PMID:35356271
Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel's Cartilage Degeneration., PMID:35347898
Elevated MMP10/13 mediated barrier disruption and NF-κB activation aggravate colitis and colon tumorigenesis in both individual or full miR-148/152 family knockout mice., PMID:34979166
MEK1/2 Inhibitor (GDC0623) Promotes Osteogenic Differentiation of Primary Osteoblasts Inhibited by IL-1β through the MEK-Erk1/2 and Jak/Stat3 Pathways., PMID:34976051
KLF4, negatively regulated by miR-7, suppresses osteoarthritis development via activating TGF-β1 signaling., PMID:34891002
Monocytes secrete CXCL7 to promote breast cancer progression., PMID:34789744
IL-40: A New B Cell-Associated Cytokine Up-Regulated in Rheumatoid Arthritis Decreases Following the Rituximab Therapy and Correlates With Disease Activity, Autoantibodies, and NETosis., PMID:34745117
Evaluation of cytokines in protective effect of docosahexaenoic acid in experimental achilles tendinopathy rat model induced with type-1 collagenase., PMID:34612118
Amelioration of post-traumatic osteoarthritis via nanoparticle depots delivering small interfering RNA to damaged cartilage., PMID:34413494
A serological type II collagen neoepitope biomarker reflects cartilage breakdown in patients with osteoarthritis., PMID:36474766
Bevacizumab Arrests Osteoarthritis Progression in a Rabbit Model: A Dose-Escalation Study., PMID:34206900
Inhibition of sphingosine 1-phosphate protects mice against chondrocyte catabolism and osteoarthritis., PMID:34144150
Denosumab alleviates intervertebral disc degeneration adjacent to lumbar fusion by inhibiting endplate osteochondral remodeling and vertebral osteoporosis in ovariectomized rats., PMID:34049577
Adalimumab Induces a Wound Healing Profile in Patients with Hidradenitis Suppurativa by Regulating Macrophage Differentiation and Matrix Metalloproteinase Expression., PMID:33965402
Advanced oxidation protein products induce inflammatory responses and invasive behaviour in fibroblast-like synoviocytes via the RAGE-NF-κB pathway., PMID:33827262
Evaluation of CCL21 role in post-knee injury inflammation and early cartilage degeneration., PMID:33651836
Frugoside delays osteoarthritis progression via inhibiting miR-155-modulated synovial macrophage M1 polarization., PMID:33493345
Proinflammatory and bone protective role of calcitonin gene-related peptide alpha in collagen antibody-induced arthritis., PMID:33221885
Maltol prevents the progression of osteoarthritis by targeting PI3K/Akt/NF-κB pathway: In vitro and in vivo studies., PMID:33211383
Non-Canonical WNT5A Signaling Through RYK Contributes to Aggressive Phenotype of the Rheumatoid Fibroblast-Like Synoviocytes., PMID:33178184
Intervening upregulated SLC7A5 could mitigate inflammatory mediator by mTOR-P70S6K signal in rheumatoid arthritis synoviocytes., PMID:32867828
For research use only. Not for human or drug use.
