Catalog No.
PHE39001
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GDF5 (Ala382-Arg501).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Growth/differentiation factor 5,BMP14,BMP-14,Radotermin,GDF-5,Bone morphogenetic protein 14,GDF5,CDMP-1,Lipopolysaccharide-associated protein 4,LAP-4,CDMP1,Cartilage-derived morphogenetic protein 1,LPS-associated protein 4
Purification
Purified by antigen affinity column.
Accession
P43026
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Human adipose-derived stromal/stem cells expressing doublecortin improve cartilage repair in rabbits and monkeys., PMID:34848747
Eukaryotic expression, Co-IP and MS identify BMPR-1B protein-protein interaction network., PMID:32471519
Lgr5 and Col22a1 Mark Progenitor Cells in the Lineage toward Juvenile Articular Chondrocytes., PMID:31522976
Enhanced chondrogenesis from human embryonic stem cells., PMID:31326745
Inhibition of microRNA-34a prevents IL-1β-induced extracellular matrix degradation in nucleus pulposus by increasing GDF5 expression., PMID:27385596
Study of CK18 and GDF5 immunoexpression in oral squamous cell carcinoma and their prognostic value., PMID:27151703
Growth without growth hormone: can growth and differentiation factor 5 be the mediator?, PMID:26393787
Peripheral Blood Mononuclear Cells Enhance Cartilage Repair in in vivo Osteochondral Defect Model., PMID:26252391
Similar cellular migration patterns from niches in intervertebral disc and in knee-joint regions detected by in situ labeling: an experimental study in the New Zealand white rabbit., PMID:24004687
GDF5 regulates TGFß-dependent angiogenesis in breast carcinoma MCF-7 cells: in vitro and in vivo control by anti-TGFß peptides., PMID:23226264
Overexpression of GDF5 through an adenovirus vector stimulates osteogenesis of human mesenchymal stem cells in vitro and in vivo., PMID:22287558
Bone marrow-derived mesenchymal stem cells obtained during arthroscopic rotator cuff repair surgery show potential for tendon cell differentiation after treatment with insulin., PMID:21978434
A prospective, randomized pilot study on the safety and efficacy of recombinant human growth and differentiation factor-5 coated onto β-tricalcium phosphate for sinus lift augmentation., PMID:20546250
GDF-5/7 and bFGF activate integrin alpha2-mediated cellular migration in rabbit ligament fibroblasts., PMID:19725104
Successful treatment with infliximab of refractory rheumatoid arthritis in a male with 'GDF5 brachydactyly'., PMID:17602228
Bone morphogenetic protein 7 increases chick photoreceptor outer segment initiation., PMID:16877437
Monomeric and dimeric GDF-5 show equal type I receptor binding and oligomerization capability and have the same biological activity., PMID:16606344
Expression of growth differentiation factor-5 and bone morphogenic protein-7 in intraocular osseous metaplasia., PMID:15965172
The homeobox transcription factor Barx2 regulates chondrogenesis during limb development., PMID:15800003
Coordination of chondrocyte differentiation and joint formation by alpha5beta1 integrin in the developing appendicular skeleton., PMID:15329344
Mutation and analysis of Dan, the founding member of the Dan family of transforming growth factor beta antagonists., PMID:11134349
Cloning and expression of recombinant human growth/differentiation factor 5., PMID:7980526
For research use only. Not for human or drug use.
