Anti-CASP2 Polyclonal Antibody

Catalog No.

PHE36001

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CASP2 (Gly334-Thr452).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Protease ICH-1,ICH1,Neural precursor cell expressed developmentally down-regulated protein 2,NEDD2,CASP-2,Caspase-2,CASP2,NEDD-2

Purification

Purified by antigen affinity column.

Accession

P42575

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Pigment epithelium-derived factor mediates retinal ganglion cell neuroprotection by suppression of caspase-2., PMID:30718480

Psoriasis Treatment Changes the Expression Profile of Selected Caspases and their Regulatory MicroRNAs., PMID:30308514

Combined suppression of CASP2 and CASP6 protects retinal ganglion cells from apoptosis and promotes axon regeneration through CNTF-mediated JAK/STAT signalling., PMID:24727569

Caspase-2 and caspase-8 trigger caspase-3 activation following 6-OHDA-induced stress in human dopaminergic neurons differentiated from ReNVM stem cells., PMID:23540413

Therapeutic activities of intravenous immunoglobulins in multiple sclerosis involve modulation of chemokine expression., PMID:19217671

Identification of a caspase-2 isoform that behaves as an endogenous inhibitor of the caspase cascade., PMID:11156409

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Anti-CASP2 Polyclonal Antibody.pdf