Catalog No.
YME14001
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ala22-Arg325
Predicted molecular weight
35.60 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P18572
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Basic immunoglobulin superfamily, Membrane glycoprotein gp42, HT7 antigen, Basigin, Bsg, CD147
Transmembrane Protease Serine 11B Modulates Lactate Transport Through SLC16A1 in Pancreatic Ductal Adenocarcinoma-A Functional Link to Phenotype Heterogeneity., PMID:40508207
Correlation between ultrasound measurements and the expression of Her-2 and CD147 in breast cancer., PMID:40385050
Serum EMMPRIN/CD147 promotes the lung pre-metastatic niche in a D2A1 mammary carcinoma mouse model., PMID:40370456
CD147 inhibition reduced fibronectin expression in TGF-β1-induced keloid fibroblasts by targeting Smad2 signaling pathway., PMID:40319830
CD147 regulates the Rap1 signaling pathway to promote proliferation, migration, and invasion, and inhibit apoptosis in colorectal cancer cells., PMID:40254691
Meplazumab, a CD147 antibody, for severe COVID-19: a double-blind, randomized, placebo-controlled, phase 3 clinical trial., PMID:40222976
Phillyrin from Forsythia suspensa suppresses the proliferation, angiogenesis, and metastasis of colorectal cancer via targeting CD147., PMID:40210179
CD147-CAR-NK cell therapy shows minimal toxicities in human CD147 transgenic mouse model with solid tumors., PMID:40160933
EMMPRIN Correlated with β-CATENIN in Various t Stages of Colorectal Adenocarcinoma., PMID:40156418
Urinary Basigin/CD147 is a useful marker of acute T cell-mediated rejection in kidney transplant recipients., PMID:40125925
CD147 Mediates the Metabolic Reprogramming of Cancer Associated Fibroblasts Induced by EVs Released by Differentiating Cancer Stem Cells., PMID:40104175
3-Hydroxybutyrate Promotes Myoblast Proliferation and Differentiation through Energy Metabolism and GPR109a-Mediated Ca2+-NFAT Signaling Pathways., PMID:40099866
Expression of MMP-14 and CD147 in Gingival Tissue of Patients With and Without Diabetes Mellitus Type II., PMID:40075856
An Anti-CD147 Antibody-Drug Conjugate Mehozumab-DM1 is Efficacious Against Hepatocellular Carcinoma in Cynomolgus Monkey., PMID:39985225
Cyclophilin-CD147 interaction enables SARS-CoV-2 infection of human monocytes and their activation via Toll-like receptors 7 and 8., PMID:39963132
iPSC-derived human cortical organoids display profound alterations of cellular homeostasis following SARS-CoV-2 infection and Spike protein exposure., PMID:39950320
In vitro expression of genes encoding HIF1α, VEGFA, PGE2 synthases, and PGE2 receptors in feline oral squamous cell carcinoma., PMID:39930728
PPIA enhances cell growth and metastasis through CD147 in oral cancer., PMID:39921142
Early Use of Liraglutide for the Treatment of Acute COVID-19 Infection: An Open-Label Single-Center Phase II Safety Study with Biomarker Profiling., PMID:39846709
CD147 mitochondria translocation induced airway remodeling in asthmatic mouse models by regulating M2 macrophage polarization via ANT1-mediated mitophagy., PMID:39740799
Basigin in cerebrovascular diseases: Roles, mechanisms, and therapeutic target potential., PMID:39734038
RNA-binding protein HuR regulates the transition of septic AKI to CKD by modulating CD147., PMID:39716463
The mitochondrial lactate oxidation complex: endpoint for carbohydrate carbon disposal., PMID:39714986
Cell membrane chromatography relative competitive method for the accurate determination of relative KD values of drug-receptor interactions., PMID:39658753
Targeting autophagy in HCC treatment: exploiting the CD147 internalization pathway., PMID:39627812
[Analysis of Endogenous Metabolite Transporters for the Development of Novel Pharmaceutical Therapies and Drug Targets]., PMID:39617467
Disruption of the Physical Interaction Between Carbonic Anhydrase IX and the Monocarboxylate Transporter 4 Impacts Lactate Transport in Breast Cancer Cells., PMID:39596062
Galectin-3 disrupts tight junctions of airway epithelial cell monolayers by inducing expression and release of matrix metalloproteinases upon influenza A infection., PMID:39569730
CD147 expression as a clinicopathological and prognostic indicator in breast cancer: a meta-analysis and bioinformatics analysis., PMID:39567919
Radioiodinated Nanobody immunoPET probe for in vivo detection of CD147 in pan-cancer., PMID:39549046
Adhesin RadD: the secret weapon of Fusobacterium nucleatum., PMID:39520704
Cyclophilin A knockdown inhibits the proliferation and metastatic ability of AGS gastric cancer stem cells by downregulating CD147/STAT3/AKT/ERK and epithelial‑mesenchymal transition., PMID:39513611
Cyclophilin A: promising target in cancer therapy., PMID:39513594
Monocarboxylate transporter dependent mechanism is involved in proliferation, migration, and invasion of human glioblastoma cell lines via activation of PI3K/Akt signaling pathway., PMID:39475905
DMF-Bimol: Counting mRNA and Protein Molecules in Single Cells with Digital Microfluidics., PMID:39428609
Expression of nuclear receptors and glucose metabolic pathway proteins in sebaceous carcinoma: Androgen receptor and monocarboxylate transporter 1 have a key role in disease progression., PMID:39421321
Engineering affinity of humanized ScFv targeting CD147 antibody: A combined approach of mCSM-AB2 and molecular dynamics simulations., PMID:39405982
Cellular and extracellular proteomic profiling of paradoxical low-flow low-gradient aortic stenosis myocardium., PMID:39355352
Effects of atorvastatin and ezetimibe on CD147, HIF-1, MMP-2 and VEGF in carotid atherosclerotic plaque under the guidance of IVUS., PMID:39348642
The Functions of SARS-CoV-2 Receptors in Diabetes-Related Severe COVID-19., PMID:39273582
Metabolic Function and Therapeutic Potential of CD147 for Hematological Malignancies: An Overview., PMID:39273126
Detection of SARS-CoV-2 binding receptors and miscellaneous targets as well as mucosal surface area of the human lacrimal drainage system., PMID:39218301
The adhesin RadD enhances Fusobacterium nucleatum tumour colonization and colorectal carcinogenesis., PMID:39169124
Receptors Involved in COVID-19-Related Anosmia: An Update on the Pathophysiology and the Mechanistic Aspects., PMID:39126095
Scalable process development of NK and CAR-NK expansion in a closed bioreactor., PMID:39114666
The binding of extracellular cyclophilin A to ACE2 and CD147 triggers psoriasis-like inflammation., PMID:39096717
Effects of SARS-COV-2 on molecules involved in vascularization and autophagy in placenta tissues., PMID:39088116
Emergence of SARS-CoV-2 omicron variant JN.1 in Tamil Nadu, India - Clinical characteristics and novel mutations., PMID:39080396
Inhibition of YIPF2 Improves the Vulnerability of Oligodendrocytes to Human Islet Amyloid Polypeptide., PMID:39078594
Rabenosyn-5 suppresses non-small cell lung cancer metastasis via inhibiting CDC42 activity., PMID:39075137