Catalog No.
YME61901
Expression system
E. coli
Species
Mus musculus (Mouse)
Protein length
Ser276-Gln521
Predicted molecular weight
29.65 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Z0M6
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Cd97, CD97, Adgre5, Leukocyte antigen CD97, Adhesion G protein-coupled receptor E5
Th1-poised naive CD4 T cell subpopulation reflects anti-tumor immunity and autoimmune disease., PMID:40000667
CD97 maintains tumorigenicity of glioblastoma stem cells via mTORC2 signaling and is targeted by CAR Th9 cells., PMID:39637858
Characterization and Physiological Differences of Two Primary Cultures of Human Normal and Hypertrophic Scar Dermal Fibroblasts: A Pilot Study., PMID:39457608
Modulation of GPR133 (ADGRD1) signaling by its intracellular interaction partner extended synaptotagmin 1., PMID:38758649
CD97 inhibits osteoclast differentiation via Rap1a/ERK pathway under compression., PMID:38311610
Anti-collagenase, Anti-elastase, Anti-urease, and Anti-cancer Potentials of Isokaempferide as Natural Compound: In vitro and in silico Study., PMID:38311409
Conformational transitions and activation of the adhesion receptor CD97., PMID:38215752
Identification of CD38, CD97, and CD278 on the HIV surface using a novel flow virometry screening assay., PMID:38155248
System analysis of surface CD markers during the process of granulocytic differentiation., PMID:38153053
sBioSITe enables sensitive identification of the cell surface proteome through direct enrichment of biotinylated peptides., PMID:38053024
Dynamic encounters with red blood cells trigger splenic marginal zone B cell retention and function., PMID:38049580
Adhesion GPCRs in glioblastoma revisited., PMID:37995190
CD97 negatively regulates the innate immune response against RNA viruses by promoting RNF125-mediated RIG-I degradation., PMID:37978243
CryoEM structures of adhesion in GPCR CD97: Filling in some of the gaps., PMID:37977125
The expression profile and tumorigenic mechanisms of CD97 (ADGRE5) in glioblastoma render it a targetable vulnerability., PMID:37938973
IL-8 is a novel prometastatic chemokine in intrahepatic cholangiocarcinoma that induces CXCR2-PI3K/AKT signaling upon CD97 activation., PMID:37907543
Structural basis of CD97 activation and G-protein coupling., PMID:37673067
Dual role of the adhesion G-protein coupled receptor ADRGE5/CD97 in glioblastoma invasion and proliferation., PMID:37517698
Highly multiplexed bioactivity screening reveals human and microbiota metabolome-GPCRome interactions., PMID:37321219
Dynamic Glycoprotein Hyposialylation Promotes Chemotherapy Evasion and Metastatic Seeding of Quiescent Circulating Tumor Cell Clusters in Breast Cancer., PMID:37272843
Optimized genetic code expansion technology for time-dependent induction of adhesion GPCR-ligand engagement., PMID:36870000
Phenotypic characterization of disease-initiating stem cells in JAK2- or CALR-mutated myeloproliferative neoplasms., PMID:36814396
CD97 expression level and its effect on cell adhesion in Preeclampsia., PMID:36572878
Single-cell protein profiling defines cell populations associated with triple-negative breast cancer aggressiveness., PMID:36550781
Differentially expressed glycoproteins in pre- and post-digital rectal examination urine samples for detecting aggressive prostate cancer., PMID:36479985
CD97 serves as a novel biomarker of immune cell infiltration in hepatocellular carcinoma., PMID:36464675
Urinary marker panels for aggressive prostate cancer detection., PMID:36050450
The Salmonella transmembrane effector SteD hijacks AP1-mediated vesicular trafficking for delivery to antigen-loading MHCII compartments., PMID:35622870
To Detach, Migrate, Adhere, and Metastasize: CD97/ADGRE5 in Cancer., PMID:35563846
Chemo- and mechanosensing by dendritic cells facilitate antigen surveillance in the spleen., PMID:35147233
CD97 promotes spleen dendritic cell homeostasis through the mechanosensing of red blood cells., PMID:35143305
CD97 is associated with mitogenic pathway activation, metabolic reprogramming, and immune microenvironment changes in glioblastoma., PMID:35087132
Enantiomer-dependent immunological response to chiral nanoparticles., PMID:35046606
Treatment of microvascular invasion in hepatocellular carcinoma with drug-loaded nanocomposite platform under synergistic effect of magnetic field/near-infrared light., PMID:34664385
CombiFlow: combinatorial AML-specific plasma membrane expression profiles allow longitudinal tracking of clones., PMID:34543390
Clinical value of CD97 and CD55 levels in the differential diagnosis of tuberculous and malignant pleural effusions., PMID:34397724
CD97 stabilises the immunological synapse between dendritic cells and T cells and is targeted for degradation by the Salmonella effector SteD., PMID:34314469
How to Obtain a Mega-Intestine with Normal Morphology: In Silico Modelling of Postnatal Intestinal Growth in a Cd97-Transgenic Mouse., PMID:34298973
Search for Novel Plasma Membrane Proteins as Potential Biomarkers in Human Mesenchymal Stem Cells Derived from Dental Pulp, Adipose Tissue, Bone Marrow, and Hair Follicle., PMID:34230997
Genetic manipulation of adhesion GPCR CD97/ADGRE5 modulates invasion in patient-derived glioma stem cells., PMID:34028660
Gene Polymorphism of MUC15, MMP14, BRAF, and COL1A1 Is Associated with Capsule Formation in Hepatocellular Carcinoma., PMID:34007838
Structural basis for CD97 recognition of the decay-accelerating factor CD55 suggests mechanosensitive activation of adhesion GPCRs., PMID:33992645
Discovery and Pharmacological Evaluation of STEAP4 as a Novel Target for HER2 Overexpressing Breast Cancer., PMID:33842315
Tethered agonist exposure in intact adhesion/class B2 GPCRs through intrinsic structural flexibility of the GAIN domain., PMID:33497605
CD36 and CD97 in Pancreatic Cancer versus Other Malignancies., PMID:32781778
CD97 Is Decreased in Preeclamptic Placentas and Promotes Human Trophoblast Invasion Through PI3K/Akt/mTOR Signaling Pathway., PMID:32430705
Author Correction: G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:32184438
G Protein-Coupling of Adhesion GPCRs ADGRE2/EMR2 and ADGRE5/CD97, and Activation of G Protein Signalling by an Anti-EMR2 Antibody., PMID:31969668
In-Depth Mapping of the Urinary N-Glycoproteome: Distinct Signatures of ccRCC-related Progression., PMID:31963743
A-to-I-edited miRNA-379-5p inhibits cancer cell proliferation through CD97-induced apoptosis., PMID:31682236
For research use only. Not for human or drug use.
