Catalog No.
PHE20301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human GPX4 (Gly73-Phe196).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PHGPx,Glutathione peroxidase 4,GPX4,GSHPx-4,GPx-4,Phospholipid hydroperoxide glutathione peroxidase
Purification
Purified by antigen affinity column.
Accession
P36969
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Targeting IL-33 to Suppress Ferroptosis and Alleviate Inflammation in Asthma Exacerbations., PMID:40499633
Nano co-inducer of immunogenic cell death and ferroptosis for anti-tumor immunotherapy., PMID:40424799
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation., PMID:40281343
Upregulation of ferroptosis in glucocorticoids-induced posterior subcapsular cataracts., PMID:40234585
Sodium butyrate increases USP5-mediated ubiquitination degradation of GPX4 and enhances anti-cancer efficacy of anti-PD-1 antibody., PMID:40216263
Transcription factor KLF5 regulates MsrB1 to promote colorectal cancer progression by inhibiting ferroptosis through β-catenin., PMID:40210135
4-1BB stimulation with concomitant inactivation of adenosine A2B receptors enhances CD8+ T cell antitumor response., PMID:40178905
Resveratrol alleviates testicular toxicity induced by anti-PD-1 through regulating the NRF2-SLC7A11-GPX4 pathway., PMID:40145083
Hsa_circ_0002301 inhibits ferroptosis in gastric cancer by encoding the de novo protein HECTD1-463aa., PMID:40022084
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis., PMID:39993549
Dulaglutide accelerates diabetic wound healing by suppressing Nrf2-dependent ferroptosis in diabetic mice., PMID:39954860
A pH-responsive PROTAC-based nanosystem triggers tumor-specific ferroptosis to construct in situ tumor vaccines., PMID:39935894
The roles of IDH2 and glutathione metabolism in cetuximab resistance in head and neck squamous cell carcinoma investigated by metabolomics and transcriptomics., PMID:39842530
T-2 toxin triggers immunotoxic effects in goats by inducing ferroptosis and neutrophil extracellular traps., PMID:39832565
Effect of the glucagon-like peptide-1 receptor agonists dulaglutide on kidney outcomes in db/db mice., PMID:39805329
Deciphering the role of TMEM164 in autophagy-mediated ferroptosis and immune modulation in non-small cell lung cancer., PMID:39798196
Enhancing Ferroptosis-Mediated Radiosensitization via Synergistic Disulfidptosis Induction., PMID:39727204
HMGA1 influence on iron-induced cell death in Tfh cells of SLE patients., PMID:39707065
Lenvatinib-activated NDUFA4L2/IL33/PADI4 pathway induces neutrophil extracellular traps that inhibit cuproptosis in hepatocellular carcinoma., PMID:39585643
Self-catalyzed nitric oxide nanocomplexes induce ferroptosis for cancer immunotherapy., PMID:39580079
SHR-1806, a robust OX40 agonist to promote T cell-mediated antitumor immunity., PMID:39543823
Sorafenib-induced macrophage extracellular traps via ARHGDIG/IL4/PADI4 axis confer drug resistance through inhibiting ferroptosis in hepatocellular carcinoma., PMID:39529192
Advances in the study of artemisinin and its derivatives for the treatment of rheumatic skeletal disorders, autoimmune inflammatory diseases, and autoimmune disorders: a comprehensive review., PMID:39524446
Rituximab induces ferroptosis and RSL3 overcomes rituximab resistance in diffuse large B-cell lymphoma cells., PMID:39490616
Chemokine CXCL13 facilitates anti-FVIII inhibitory antibody development in hemophilia A patients and murine models., PMID:39471695
Immunohistochemical examination of immunoreactivity of transient receptor potential melastatin 2, glutathione peroxidase 4 and spexin in lichen planus., PMID:39400728
Integrative microbiomics, proteomics and lipidomics studies unraveled the preventive mechanism of Shouhui Tongbian Capsules on cerebral ischemic stroke injury., PMID:39362332
β-glucan nanoparticles alleviate acute asthma by suppressing ferroptosis and DNA damage in mice., PMID:39305381
Glutathione-Disrupting Nanotherapeutics Potentiate Ferroptosis for Treating Luminal Androgen Receptor-Positive Triple-Negative Breast Cancer., PMID:39287044
4-Hydroxychalcone attenuates ovalbumin-induced allergic airway inflammation and oxidative stress by activating Nrf2/GPx4 pathway., PMID:39260757
Licochalcone A mitigates aflatoxin B1-induced immunotoxicity via ferroptosis in bursa of broilers and macrophages., PMID:39106705
Inhibition of ferroptosis rescues M2 macrophages and alleviates arthritis by suppressing the HMGB1/TLR4/STAT3 axis in M1 macrophages., PMID:39029270
Genetically Engineered Membrane-Coated Nanoparticles for Enhanced Prostate-Specific Membrane Antigen Targeting and Ferroptosis Treatment of Castration-Resistant Prostate Cancer., PMID:38946578
Inhibition of ER stress using tauroursodeoxycholic acid rescues obesity-evoked cardiac remodeling and contractile anomalies through regulation of ferroptosis., PMID:38906502
ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis., PMID:38756246
Correction: Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/ GPX4 expression., PMID:38693552
Targeting FTO induces colorectal cancer ferroptotic cell death by decreasing SLC7A11/GPX4 expression., PMID:38600610
Prevention of bleomycin-induced pulmonary fibrosis by vaccination with the Tocilizumab mimotope., PMID:38408907
A pH-responsive cetuximab-conjugated DMAKO-20 nano-delivery system for overcoming K-ras mutations and drug resistance in colorectal carcinoma., PMID:38331131
Anti-NOTCH1 therapy with OMP-52 M51 inhibits salivary adenoid cystic carcinoma by depressing epithelial-mesenchymal transition (EMT) process and inducing ferroptosis., PMID:38253083
The oxidized phospholipid PGPC impairs endothelial function by promoting endothelial cell ferroptosis via FABP3., PMID:38218337
STING upregulation mediates ferroptosis and inflammatory response in lupus nephritis by upregulating TBK1 and activating NF-κB signal pathway., PMID:38186000
Influence of ferroptosis indicators on the stability of atherosclerotic plaque., PMID:38158665
Identification of Diagnosis and Typological Characteristics Associated with Ferroptosis for Ulcerative Colitis via Bioinformatics and Machine Learning., PMID:37957905
Deubiquitinase inhibitor PR-619 potentiates colon cancer immunotherapy by inducing ferroptosis., PMID:37526037
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction., PMID:37392951
Ferroptosis participates in dibutyl phthalate-aggravated allergic asthma in ovalbumin-sensitized mice., PMID:37018853
B cell-derived anti-beta 2 glycoprotein I antibody mediates hyperhomocysteinemia-aggravated hypertensive glomerular lesions by triggering ferroptosis., PMID:36907919
Blocking EREG/GPX4 Sensitizes Head and Neck Cancer to Cetuximab through Ferroptosis Induction., PMID:36899869
Targeting ferroptosis: Paving new roads for drug design and discovery., PMID:36543035
For research use only. Not for human or drug use.
