Catalog No.
YHK88901
Expression system
E. coli
Species
Homo sapiens (Human)
Protein length
Met1-Asn252
Predicted molecular weight
28.92 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q9Y2G4
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Ankyrin repeat domain-containing protein 6, ANKRD6, KIAA0957, Diversin
WNT signaling pathway and stem cell signaling network. PMID: 17634527
WNT/PCP signaling pathway and human cancer (review). PMID: 16273260
Identification of crucial genes in abdominal aortic aneurysm by WGCNA. PMID: 31608184
Planar cell polarity regulators in asymmetric organogenesis during development and disease. PMID: 35809777
Pan-cancer analyses demonstrate that ANKRD6 is associated with a poor prognosis and correlates with M2 macrophage infiltration in colon cancer. PMID: 33707932
Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. PMID: 25218921
Identification and characterization of rat Ankrd6 gene in silico. PMID: 15647854
Expression of the ankyrin repeat domain 6 gene (Ankrd6) during mouse brain development. PMID: 12203740
Variants of the ankyrin repeat domain 6 gene (ANKRD6) and muscle and physical activity phenotypes among European-derived American adults. PMID: 22580979
Genetic studies of ANKRD6 as a molecular switch between Wnt signaling pathways in human neural tube defects. PMID: 25200652
Proteomic analysis of the follicular fluid of Tianzhu white yak during diestrus. PMID: 24633201
Role of miR-214 in regulation of β-catenin and the malignant phenotype of melanoma. PMID: 31338875
Mechanisms of neurogenesis in the normal and injured adult brain. PMID: 23563788
Comparative integromics on FAT1, FAT2, FAT3 and FAT4. PMID: 16865240
Genome-wide identification and annotation of SNPs and their mapping in candidate genes related to milk production and fertility traits in Badri cattle. PMID: 36928332
Roles of planar cell polarity pathways in the development of neural [correction of neutral] tube defects. PMID: 21864354
Differentially methylated genes in proliferative verrucous leukoplakia reveal potential malignant biomarkers for oral squamous cell carcinoma. PMID: 33657465
Cuproptosis-Mediated Patterns Characterized by Distinct Tumor Microenvironment and Predicted the Immunotherapy Response for Gastric Cancer. PMID: 37008098
Different expression of lipid metabolism-related genes in Shandong black cattle and Luxi cattle based on transcriptome analysis. PMID: 33318614
Comparative genomics on Vangl1 and Vangl2 genes. PMID: 15809738
Centrosomal localization of Diversin and its relevance to Wnt signaling. PMID: 19789178
Genome-wide association study reveals genetic loci and candidate genes for meat quality traits in a four-way crossbred pig population. PMID: 36814900
Diversin upregulates the proliferative ability of colorectal cancer by inducing cell cycle proteins. PMID: 36623636
Regulation of basal body and ciliary functions by Diversin. PMID: 21843637
Diversin is overexpressed in breast cancer and accelerates cell proliferation and invasion. PMID: 24858714
Diversin increases the proliferation and invasion ability of non-small-cell lung cancer cells via JNK pathway. PMID: 24246849
Diversin is overexpressed in human gliomas and its depletion inhibits proliferation and invasion. PMID: 24833088
Frat oncoproteins act at the crossroad of canonical and noncanonical Wnt-signaling pathways. PMID: 19802005
Polarized translocation of fluorescent proteins in Xenopus ectoderm in response to Wnt signaling. PMID: 21654626
The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9. PMID: 19591803
Expression and proliferation-promoting role of Diversin in the neuronally committed precursor cells migrating in the adult mouse brain. PMID: 20827749
The ankyrin repeat protein Diversin recruits Casein kinase Iepsilon to the beta-catenin degradation complex and acts in both canonical Wnt and Wnt/JNK signaling. PMID: 12183362
For research use only. Not for human or drug use.
