Anti-PTGS2 Polyclonal Antibody

Catalog No.

PHE10101

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PTGS2 (Phe187-Asn425).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

PGH synthase 2,Prostaglandin G/H synthase 2,Cyclooxygenase-2,PTGS2,COX2,PGHS-2,PHS II,Prostaglandin-endoperoxide synthase 2,COX-2,Prostaglandin H2 synthase 2

Purification

Purified by antigen affinity column.

Accession

P35354

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Cyclooxygenase-2 Overexpression and its Association with Histopathological Features of Human Malignant Melanoma., PMID:40487258

Therapeutic potential of Coprinus comatus nanogels: Antiarthritic and anti-inflammatory effects in rheumatoid arthritis models., PMID:40342737

Puriton attenuates the asthma severity in ovalbumin-induced murine model via balancing Th1/Th2 and inhibiting inflammation., PMID:40323927

Secretory IgA binding to FCRL3 triggers shared inflammatory cytokine secretion by human regulatory T cells and effector T cells., PMID:40313182

Expression of cyclooxygenase-2 (COX-2) in epithelial ovarian cancers in an Indigenous African population of Kano, Nigeria., PMID:40248271

Expression of cyclooxygenase-2 (COX-2) in colorectal carcinoma in an indigenous African population of Kano, Nigeria., PMID:40171463

IgA2 ACPA Drives a Hyper-Inflammatory Phenotype in Macrophages via ATP Synthase and COX2., PMID:40170376

IL-33 facilitates endoplasmic reticulum stress and pyroptosis in LPS-stimulated ARDS model in vitro., PMID:40118005

Ameliorative Effects of Escin on Inflammation via Glucocorticoid Receptor (GR) in Atopic Dermatitis (AD) Mouse Model., PMID:40081901

Effect of the glucagon-like peptide-1 receptor agonists dulaglutide on kidney outcomes in db/db mice., PMID:39805329

Celecoxib Combined with Tocilizumab Has Anti-Inflammatory Effects and Promotes the Recovery of Damaged Cartilage via the Nrf2/HO-1 Pathway In Vitro., PMID:39766343

Effects of Crescentia cujete (L.) fruit extract on the profile of hematology of ranchu goldfish (Carassius auratus)., PMID:39737036

Impact of Lysine to Methionine Ratios on Antioxidant Capacity and Immune Function in the Rumen of Tibetan Sheep: An RNA-Seq Analysis., PMID:39708312

Activation of mixed lineage kinase 3 by fine particulate matter induces skin inflammation in human keratinocytes., PMID:39547318

Screening of anti-inflammatory active components in Sabia schumanniana Diels by affinity ultrafiltration and UHPLC-Q-Exactive Orbitrap mass spectrometry., PMID:39306211

In vitro analysis of VEGF-mediated endothelial permeability and the potential therapeutic role of Anti-VEGF in severe dengue., PMID:39263317

Guaijaverin And Epigallocatechin Gallate Exerts Antiinflammatory And Antiallergenic Effects Through Interleukin-12 Production., PMID:39229731

Immune-mediated impairment of tonic immobility defensive behavior in an experimental model of colonic inflammation., PMID:39218820

Lumbrokinase Extracted from Earthworms Synergizes with Bevacizumab and Chemotherapeutics in Treating Non-Small Cell Lung Cancer by Targeted Inactivation of BPTF/VEGF and NF-κB/COX-2 Signaling., PMID:39062456

Combining Anti-Mitochondrial Antibodies, Anti-Histone, and PLA2/COX Biomarkers to Increase Their Diagnostic Accuracy for Autism Spectrum Disorders., PMID:38928576

PGE2 induced miR365/IL-6/STAT3 signaling mediates dendritic cell dysfunction in cancer., PMID:38797363

ANO6 (TMEM16F) inhibits gastrointestinal stromal tumor growth and induces ferroptosis., PMID:38756246

PM2.5 exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF-κB pathway., PMID:38657455

Xin-Yi-Qing-Fei-Tang and its critical components reduce asthma symptoms by suppressing GM-CSF and COX-2 expression in RBL-2H3 cells., PMID:38631485

Smoking enhances proliferation, inflammatory markers, and immunoglobulins in peripheral blood mononuclear cells from Graves' patients., PMID:38614122

The inositol-requiring enzyme 1 (IRE1) endoplasmic reticulum stress pathway promotes MDA-MB-231 cell survival and renewal in response to the aryl-ureido fatty acid CTU., PMID:38608921

Induction of human-fetal-membrane remodeling in-vitro by the alpha hemolysin of Escherichia coli., PMID:38401207

Antagonism of regulatory ISGs enhances the anti-melanoma efficacy of STING agonists., PMID:38312842

Inflammation-Driven Nanohitchhiker Enhances Postoperative Immunotherapy by Alleviating Prostaglandin E2-Mediated Immunosuppression., PMID:38300288

Endocannabinoid regulation in the cervix during pregnancy: insights into molecular mechanisms of premature labor., PMID:38271800

Treponema pallidum protein Tp47 induced prostaglandin E2 to inhibit the phagocytosis in human macrophages., PMID:38258964

M1 macrophage-derived oncostatin M induces osteogenic differentiation of ligamentum flavum cells through the JAK2/STAT3 pathway., PMID:38222812

Codelivery of TGFβ and Cox2 siRNA inhibits HCC by promoting T-cell penetration into the tumor and improves response to Immune Checkpoint Inhibitors., PMID:38204925

Microbiota promotes recruitment and pro-inflammatory response of caecal macrophages during E. tenella infection., PMID:38098020

Blockade of EP4 by ASP7657 Modulates Myeloid Cell Differentiation In Vivo and Enhances the Antitumor Effect of Radiotherapy., PMID:38058393

Anti-CMV therapy, what next? A systematic review., PMID:38053548

Extra-adrenal aldosterone: a mini review focusing on the physiology and pathophysiology of intrarenal aldosterone., PMID:37847370

Molecular Insights into the Macrophage Immunomodulatory Effects of Scrophulariae Radix Polysaccharides., PMID:37830509

LPS/TLR4 Pathway Regulates IgA1 Secretion to Induce IgA Nephropathy., PMID:37820669

Celecoxib-Loaded Cubosomal Nanoparticles as a Therapeutic Approach for Staphylococcus aureus In Vivo Infection., PMID:37764091

The Functional Role of Myogenin in Cardiomyoblast H9c2 Cells Treated with High Glucose and Palmitic Acid: Insights into No-Rejection Heart Transplantation., PMID:37685838

New investigation of anti-inflammatory activity of Polycladia crinita and biosynthesized selenium nanoparticles: isolation and characterization., PMID:37670273

Analysis of a new therapeutic target and construction of a prognostic model for breast cancer based on ferroptosis genes., PMID:37643511

ER and COX2 expression in endometrial hyperplasia processes., PMID:37603513

β2-adrenergic receptor expression in patients receiving bevacizumab therapy for metastatic melanoma., PMID:37551424

BTK inhibition potentiates anti-PD-L1 treatment in murine melanoma: potential role for MDSC modulation in immunotherapy., PMID:37528320

Cineole inhibits the biosynthesis of leukotrienes and prostaglandins to alleviate allergic rhinitis: Insights from metabolomics., PMID:37481900

Involvement of the visfatin/toll-like receptor 4 signaling axis in human dental pulp cell senescence: Protection via toll-like receptor 4 blockade., PMID:37404665

Origanum majorana L. protects against neuroinflammation-mediated cognitive impairment: a phyto-pharmacological study., PMID:37210483

Immunohistochemical evaluation of cyclooxygenase-2 and mast cell density in periapical lesions., PMID:37171246

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