Catalog No.
PHB25401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human RPS6KA5 (Met1-Phe348).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
RPS6KA5, RSK-like protein kinase, MSK1, Ribosomal protein S6 kinase alpha-5, Nuclear mitogen- and stress-activated protein kinase 1, 90 kDa ribosomal protein S6 kinase 5, RSKL, S6K-alpha-5
Purification
Purified by antigen affinity column.
Accession
O75582
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Involvement of mitogen- and stress-activated protein kinase 1 in BMP-6-induced chondrocyte differentiation., PMID:39307301
A panel of autoantibodies against tumor-associated antigens in the early immunodiagnosis of lung cancer., PMID:31980218
Discovering novel lung cancer associated antigens and the utilization of their autoantibodies in detection of lung cancer., PMID:31839396
Expression patterns of C1ql4 and its cell-adhesion GPCR Bai3 in the murine testis and functional roles in steroidogenesis., PMID:30608882
[IL-33 promotes airway remodeling in a mouse model of asthma via ERK1/2 signaling pathway]., PMID:27126934
CCN1 acutely increases nitric oxide production via integrin αvβ3-Akt-S6K-phosphorylation of endothelial nitric oxide synthase at the serine 1177 signaling axis., PMID:26393424
Screening of the Human Kinome Identifies MSK1/2-CREB1 as an Essential Pathway Mediating Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication during Primary Infection., PMID:26109721
The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation., PMID:24519526
Spatiotemporal patterns and essential role of MSK1 expression after rat spinal cord injury., PMID:24142296
The AGC kinase inhibitor H89 attenuates airway inflammation in mouse models of asthma., PMID:23189147
MSK1 regulates environmental enrichment-induced hippocampal plasticity and cognitive enhancement., PMID:23077336
Breast tumor-associated osteoblast-derived CXCL5 increases cancer progression by ERK/MSK1/Elk-1/snail signaling pathway., PMID:23045282
Dimethylfumarate inhibits MIF-induced proliferation of keratinocytes by inhibiting MSK1 and RSK1 activation and by inducing nuclear p-c-Jun (S63) and p-p53 (S15) expression., PMID:21340650
Polycomb group protein displacement and gene activation through MSK-dependent H3K27me3S28 phosphorylation., PMID:20864036
Adalimumab therapy rapidly inhibits p38 mitogen-activated protein kinase activity in lesional psoriatic skin preceding clinical improvement., PMID:20346019
L-DOPA activates ERK signaling and phosphorylates histone H3 in the striatonigral medium spiny neurons of hemiparkinsonian mice., PMID:19187092
TNFR1 and TNFR2 signaling interplay in cardiac myocytes., PMID:17913704
Spatiotemporal pattern of striatal ERK1/2 phosphorylation in a rat model of L-DOPA-induced dyskinesia and the role of dopamine D1 receptors., PMID:17662258
Mitogen- and stress-activated protein kinase 2 and cyclic AMP response element binding protein are activated in lesional psoriatic epidermis., PMID:17429437
Mitogen- and stress-activated protein kinase 1 is activated in lesional psoriatic epidermis and regulates the expression of pro-inflammatory cytokines., PMID:16543895
Involvement of ERKs and mitogen- and stress-activated protein kinase in UVC-induced phosphorylation of ATF2 in JB6 cells., PMID:15192015
Tumor necrosis factor activates CRE-binding protein through a p38 MAPK/MSK1 signaling pathway in endothelial cells., PMID:14761884
WNK1, the kinase mutated in an inherited high-blood-pressure syndrome, is a novel PKB (protein kinase B)/Akt substrate., PMID:14611643
The receptor for advanced glycation end-products (RAGE) directly binds to ERK by a D-domain-like docking site., PMID:12935895
Shear stress-mediated chromatin remodeling provides molecular basis for flow-dependent regulation of gene expression., PMID:12805238
Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway., PMID:12763138
Lysophosphatidic acid stimulates CREB through mitogen- and stress-activated protein kinase-1., PMID:12763014
[Cloning and tissue expressive pattern analysis of the human ribosomal S6 kinase-RPS6KA5 cDNA]., PMID:12548975
Metabolic and mitogenic signal transduction in human skeletal muscle after intense cycling exercise., PMID:12527721
Post-streptococcal nonallergic urticaria?, PMID:12028126
Marathon running increases ERK1/2 and p38 MAP kinase signalling to downstream targets in human skeletal muscle., PMID:11579175
The nucleosomal response associated with immediate-early gene induction is mediated via alternative MAP kinase cascades: MSK1 as a potential histone H3/HMG-14 kinase., PMID:10469656
For research use only. Not for human or drug use.
