Catalog No.
PHA92301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human ACSL4 (Lys500-Lys711).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ACS4, ACSL4, Long-chain-fatty-acid--CoA ligase 4, LACS 4, Arachidonate--CoA ligase, FACL4, Long-chain acyl-CoA synthetase 4, LACS4
Purification
Purified by antigen affinity column.
Accession
O60488
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Endothelial but not systemic ferroptosis inhibition protects from antineutrophil cytoplasmic antibody-induced crescentic glomerulonephritis., PMID:40122342
Gancao Xiexin decoction attenuated experimental colitis through suppressing ACSL4-mediated ferroptosis., PMID:39993549
Effect of the glucagon-like peptide-1 receptor agonists dulaglutide on kidney outcomes in db/db mice., PMID:39805329
TMOD3 accelerated resistance to immunotherapy in KRAS-mutated pancreatic cancer through promoting autophagy-dependent degradation of ASCL4., PMID:39531951
Integrative microbiomics, proteomics and lipidomics studies unraveled the preventive mechanism of Shouhui Tongbian Capsules on cerebral ischemic stroke injury., PMID:39362332
CX-5461 ameliorates disease in lupus-prone mice by triggering B-cell ferroptosis via p53-SLC7A11-ALOX12 pathway., PMID:39111584
Licochalcone A mitigates aflatoxin B1-induced immunotoxicity via ferroptosis in bursa of broilers and macrophages., PMID:39106705
STING upregulation mediates ferroptosis and inflammatory response in lupus nephritis by upregulating TBK1 and activating NF-κB signal pathway., PMID:38186000
Methylation Regulation of LPCAT3 Improves Osteoarthritis by Regulating ACSL4 to Inhibit Chondrocyte Ferroptosis., PMID:38073444
Knockdown of JMJD3 ameliorates cigarette smoke extract-triggered bronchial epithelial cell injury via ACSL4-dependent ferroptosis., PMID:37967773
CYP1B1 inhibits ferroptosis and induces anti-PD-1 resistance by degrading ACSL4 in colorectal cancer., PMID:37059712
Downregulation of PPARα mediates FABP1 expression, contributing to IgA nephropathy by stimulating ferroptosis in human mesangial cells., PMID:36147466
Glia maturation factor-β induces ferroptosis by impairing chaperone-mediated autophagic degradation of ACSL4 in early diabetic retinopathy., PMID:35325805
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545
Giardia lamblia: Identification of peroxisomal-like proteins., PMID:29913139
Tyrosine phosphates act on steroidogenesis through the activation of arachidonic acid release., PMID:15666802
For research use only. Not for human or drug use.
