Catalog No.
PHJ23401
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human IL17RC (Asn257-Asn477).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
IL-17RC, IL-17RL, ZcytoR14, Interleukin-17 receptor C, Interleukin-17 receptor homolog, IL17Rhom, IL17RC, IL-17 receptor C, Interleukin-17 receptor-like protein
Purification
Purified by antigen affinity column.
Accession
Q8NAC3
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Neuronal Mechanisms of Psoriatic Itch: Role of IL-17R/ERK/TRPV4 Signaling Pathway., PMID:40252992
Genetic polymorphisms to identify patients with an optimal response to tildrakizumab in psoriasis patients from real-life clinical practice., PMID:39081053
Biomass-related PM2.5 induced inflammatory microenvironment via IL-17F/IL-17RC axis., PMID:38036089
IL-17 receptor A functions to help maintain barrier integrity and limit activation of immunopathogenic response to H. pylori infection., PMID:38014948
Differential effects of interleukin-17A and 17F on cell interactions between immune cells and stromal cells from synovium or skin., PMID:37932356
IL-17A inhibitor-induced leucocytoclastic vasculitis is responsive to IL-23 blockade in a psoriatic arthritis patient., PMID:37679036
Interleukin-17A knockout or self-recovery alleviated autoimmune reaction induced by fluoride in mouse testis., PMID:37086998
Synoviocytes and skin fibroblasts show opposite effects on IL-23 production and IL-23 receptor expression during cell interactions with immune cells., PMID:36088336
Expression and activity of IL-17 receptor subunits in human cutaneous cells as targets for anti-IL-17 therapeutic antibodies., PMID:35062060
Interleukin-17A Causes Osteoarthritis-Like Transcriptional Changes in Human Osteoarthritis-Derived Chondrocytes and Synovial Fibroblasts In Vitro., PMID:34054865
IL-17 drives salivary gland dysfunction via inhibiting TRPC1-mediated calcium movement in Sjögren's syndrome., PMID:33968407
Conformational dynamics in interleukin 17A and 17F functional complexes is a key determinant of receptor A affinity and specificity., PMID:33706174
Intestinal IL-17R Signaling Controls Secretory IgA and Oxidase Balance in Citrobacter rodentium Infection., PMID:33431657
Dual neutralisation of IL-17F and IL-17A with bimekizumab blocks inflammation-driven osteogenic differentiation of human periosteal cells., PMID:32723833
Expression Levels of IL-17A, IL-17F, IL-17RA, and IL-17RC in Prostate Cancer with Taking into Account the Histological Grade according to Gleason Scale in Comparison to Benign Prostatic Hyperplasia: In Search of New Therapeutic Options., PMID:32537467
Cajanonic acid A regulates the ratio of Th17/Treg via inhibition of expression of IL-6 and TGF-β in insulin-resistant HepG2 cells., PMID:31729529
IL-17A neutralizing antibody attenuates eosinophilic meningitis caused by Angiostrongylus cantonensis by involving IL-17RA/Traf6/NF-κB signaling., PMID:31415761
Neutrophils and IL17A mediate flagellar hook protein FlgE-induced mouse acute lung inflammation., PMID:30412932
Act1 is a negative regulator in T and B cells via direct inhibition of STAT3., PMID:30013031
Immune Cell Production of Interleukin 17 Induces Stem Cell Features of Pancreatic Intraepithelial Neoplasia Cells., PMID:29604293
IL-17A, IL-17RC polymorphisms and IL17 plasma levels in Tunisian patients with rheumatoid arthritis., PMID:29584788
The human IL-17A/F heterodimer: a two-faced cytokine with unique receptor recognition properties., PMID:28827714
Psoriatic inflammation causes hepatic inflammation with concomitant dysregulation in hepatic metabolism via IL-17A/IL-17 receptor signaling in a murine model., PMID:27773660
Immune analysis of expression of IL-17 relative ligands and their receptors in bladder cancer: comparison with polyp and cystitis., PMID:27716046
Generation and characterization of ixekizumab, a humanized monoclonal antibody that neutralizes interleukin-17A., PMID:27143947
Interleukin-17A Induces IL-1β Secretion From RPE Cells Via the NLRP3 Inflammasome., PMID:26830368
Targeting IL-17 and IL-23 in Immune Mediated Renal Disease., PMID:26521930
IL-17 Enhances Chemotaxis of Primary Human B Cells during Asthma., PMID:25494178
Heterogeneous expression pattern of interleukin 17A (IL-17A), IL-17F and their receptors in synovium of rheumatoid arthritis, psoriatic arthritis and osteoarthritis: possible explanation for nonresponse to anti-IL-17 therapy?, PMID:25146432
The selective anti-IL17A monoclonal antibody secukinumab (AIN457) attenuates IL17A-induced levels of IL6 in human astrocytes., PMID:24677511
Early tissue responses in psoriasis to the antitumour necrosis factor-α biologic etanercept suggest reduced interleukin-17 receptor expression and signalling., PMID:24601997
Propionibacterium acnes Induces an IL-17 Response in Acne Vulgaris that Is Regulated by Vitamin A and Vitamin D., PMID:23924903
The role of interleukin 17 in Crohn's disease-associated intestinal fibrosis., PMID:23834907
Negative feedback on IL-23 exerted by IL-17A during pulmonary inflammation., PMID:23295184
Th17 cells upregulate polymeric Ig receptor and intestinal IgA and contribute to intestinal homeostasis., PMID:22993206
Effect of interleukin-17 on the expression of chemokines in gingival epithelial cells., PMID:21896049
Interleukin-17F affects cartilage matrix turnover by increasing the expression of collagenases and stromelysin-1 and by decreasing the expression of their inhibitors and extracellular matrix components in chondrocytes., PMID:21885294
IL-17A induces CCL28, supporting the chemotaxis of IgE-secreting B cells., PMID:21447959
Role of interleukin 17 in arthritis chronicity through survival of synoviocytes via regulation of synoviolin expression., PMID:20976214
Evidence for a cross-talk between human neutrophils and Th17 cells., PMID:19890092
Expression of interleukin-17RC protein in normal human tissues., PMID:18928529
Differential expression of IL-17RC isoforms in androgen-dependent and androgen-independent prostate cancers., PMID:17603628
Soluble and transmembrane isoforms of novel interleukin-17 receptor-like protein by RNA splicing and expression in prostate cancer., PMID:11706037
For research use only. Not for human or drug use.
