Catalog No.
PHD98101
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD66b/CEACAM8 (Gln35-Asp320).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
CD67 antigen,Carcinoembryonic antigen CGM6,Carcinoembryonic antigen-related cell adhesion molecule 8,CGM6,CD66b,Non-specific cross-reacting antigen NCA-95,CEACAM8
Purification
Purified by antigen affinity column.
Accession
P31997
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Immune suppressive activities of low-density neutrophils in sepsis and potential use as a novel biomarker of sepsis-induced immune suppression., PMID:40108283
Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression., PMID:39838375
Immune complexes-mediated activation of neutrophils in systemic lupus erythematosus is dependent on RNA recognition by toll-like receptor 8., PMID:39776899
Neutrophils in the Spotlight-An Analysis of Neutrophil Function and Phenotype in ARDS., PMID:39684262
A whole blood-based functional assay to characterize immunoglobulin A effector functions., PMID:38616577
Flow Cytometry as an Alternative to Microscopy for the Differentiation of BAL Fluid Leukocytes., PMID:38548099
Exosomal miRNAs from neutrophils act as accurate biomarkers for gastric cancer diagnosis., PMID:38199579
A Point-of-Care Diagnostic Platform for Detecting Host Immune Activation due to Infections: Cytocapture of Biomarkers In Situ (CyBIS)., PMID:40083713
Functional Analysis of a Novel Complement C5a Receptor 1-Blocking Monoclonal Antibody., PMID:37952515
MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer., PMID:37644468
Optimization of Radiolabeling of a [90Y]Y-Anti-CD66-Antibody for Radioimmunotherapy before Allogeneic Hematopoietic Cell Transplantation., PMID:37509321
Immunoregulatory functions of mature CD10+ and immature CD10- neutrophils in sepsis patients., PMID:36687441
Multiplex immunofluorescence and single-cell transcriptomic profiling reveal the spatial cell interaction networks in the non-small cell lung cancer microenvironment., PMID:36588094
Immune complex-mediated neutrophil activation in patients with polymyalgia rheumatica., PMID:36562570
Peripheral blood mononuclear cell phenotype and function are maintained after overnight shipping of whole blood., PMID:36402888
A comprehensive assessment of four whole blood stabilizers for flow-cytometric analysis of leukocyte populations., PMID:36279192
"Rogue" neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury - studies in human, macaque and rat LPS-inflammation models., PMID:36275710
Neutrophil extracellular traps promote thrombogenicity in cerebral venous sinus thrombosis., PMID:35869501
Ocular Surface Immune Cell Profiles in Contact Lens-Induced Discomfort., PMID:35857328
Antibody-functionalized aluminum oxide-coated particles targeting neutrophil receptors in a multifrequency microfluidic impedance cytometer., PMID:35851596
Discovery of Biomarkers of Resistance to Immune Checkpoint Blockade in NSCLC Using High-Plex Digital Spatial Profiling., PMID:35490853
A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders., PMID:35362257
Oral Neutrophil Free Fatty Acid Receptors Expression May Link Oral Host and Microbiome Lipid Metabolism., PMID:35320973
Comprehensive Immune Profiling Reveals CD56+ Monocytes and CD31+ Endothelial Cells Are Increased in Severe COVID-19 Disease., PMID:34987111
The profile of inflammatory extracellular vesicles in intracerebral hemorrhage patients., PMID:40129971
Autoantibodies to red blood cell surface Glycophorin A impact the activation poise of circulating leukocytes., PMID:34796962
Immunoglobulin G Immune Complexes May Contribute to Neutrophil Activation in the Course of Severe Coronavirus Disease 2019., PMID:34398243
High expression of neutrophil and monocyte CD64 with simultaneous lack of upregulation of adhesion receptors CD11b, CD162, CD15, CD65 on neutrophils in severe COVID-19., PMID:34377464
IgG and IgA autoantibodies against L1 ORF1p expressed in granulocytes correlate with granulocyte consumption and disease activity in pediatric systemic lupus erythematosus., PMID:34051843
Blood neutrophils from children with COVID-19 exhibit both inflammatory and anti-inflammatory markers., PMID:33979758
Immuno-profiling and cellular spatial analysis using five immune oncology multiplex immunofluorescence panels for paraffin tumor tissue., PMID:33875760
Invasive Fungal Diseases in Children with Hematological Malignancies Treated with Therapies That Target Cell Surface Antigens: Monoclonal Antibodies, Immune Checkpoint Inhibitors and CAR T-Cell Therapies., PMID:33807678
Investigation of the response of tear-film neutrophils to interleukin 8 and their sensitivity to centrifugation, fixation, and incubation., PMID:33184318
Anti-Apolipoprotein A-1 IgG Influences Neutrophil Extracellular Trap Content at Distinct Regions of Human Carotid Plaques., PMID:33086507
Development of a Flow Cytometry-Based Functional Assay to Study Anti-TNF Mechanisms of Action and Capture Donor Heterogeneity., PMID:33067400
Neutrophil subpopulations and their activation potential in patients with antiphospholipid syndrome and healthy individuals., PMID:33026085
Myeloid-Derived Suppressor Cells Promote the Progression of Primary Membranous Nephropathy by Enhancing Th17 Response., PMID:32973748
Enhanced closed eye neutrophil degranulation in dry eye disease., PMID:32889089
FLAER Based Assay According to Newer Guidelines Increases Sensitivity of PNH Clone Detection., PMID:32647428
Ovarian endometrioma infiltrating neutrophils orchestrate immunosuppressive microenvironment., PMID:32334621
Association between local immune cell infiltration, mismatch repair status and systemic inflammatory response in colorectal cancer., PMID:32316975
Differentiation and activation of eosinophils in the human bone marrow during experimental human endotoxemia., PMID:31922294
Characterization of cell-derived microparticles in synovial fluid and plasma of patients with rheumatoid arthritis., PMID:31201512
Optimizing the Method of Cell Separation from Bile of Patients with Cholangiocarcinoma for Flow Cytometry., PMID:31191647
Tumor-associated neutrophils induce EMT by IL-17a to promote migration and invasion in gastric cancer cells., PMID:30616627
Tumor-Contacted Neutrophils Promote Metastasis by a CD90-TIMP-1 Juxtacrine-Paracrine Loop., PMID:30482778
Intravenous immunoglobulin replacement treatment reduces in vivo elastase secretion in patients with common variable immune disorders., PMID:30036181
The prognostic values of tumor-infiltrating neutrophils, lymphocytes and neutrophil/lymphocyte rates in bladder urothelial cancer., PMID:29803657
Value of CD16/CD66b/CD45 in comparison to CD55/CD59/CD45 in diagnosis of paroxysmal nocturnal haemoglobinuria: An Indian experience., PMID:29355143
Analogous detection of circulating tumor cells using the AccuCyte® -CyteFinder® system and ISET system in patients with locally advanced and metastatic prostate cancer., PMID:29285777
For research use only. Not for human or drug use.
