Anti-ABCA3 Polyclonal Antibody

Catalog No.

PHJ46601

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human ABCA3 (Asp1358-Phe1635).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

ABCA3, ATP-binding cassette sub-family A member 3, Phospholipid-transporting ATPase ABCA3, ABC3, ATP-binding cassette 3, ATP-binding cassette transporter 3, ABC-C transporter, Xenobiotic-transporting ATPase ABCA3

Purification

Purified by antigen affinity column.

Accession

Q99758

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

The Role of Pulmonary Genetic Variations in the Pathogenesis of Pediatric Postinfectious Bronchiolitis Obliterans., PMID:40196942

Functional Genomics of ABCA3 Variants., PMID:32692933

Functional Characterization of ATP-Binding Cassette Transporter A3 Mutations from Infants with Respiratory Distress Syndrome., PMID:27374344

Tools to explore ABCA3 mutations causing interstitial lung disease., PMID:27177387

MAPK and JAK-STAT signaling pathways are involved in the oxidative stress-induced decrease in expression of surfactant protein genes., PMID:22739240

Annexin A7 and SNAP23 interactions in alveolar type II cells and in vitro: a role for Ca(2+) and PKC., PMID:22713544

Secretagogues of lung surfactant increase annexin A7 localization with ABCA3 in alveolar type II cells., PMID:21911013

Exosomal evasion of humoral immunotherapy in aggressive B-cell lymphoma modulated by ATP-binding cassette transporter A3., PMID:21873242

The milieu of damaged alveolar epithelial type 2 cells stimulates alveolar wound repair by endogenous and exogenous progenitors., PMID:21700959

Some ABCA3 mutations elevate ER stress and initiate apoptosis of lung epithelial cells., PMID:21214890

Monoclonal antibody 7F9 recognizes rat protein homologous to human carboxypeptidase-M in developing and adult rat lung., PMID:17207026

Expression of ABCA3 in developing lung and other tissues., PMID:16982851

Cloning of ABCA17, a novel rodent sperm-specific ABC (ATP-binding cassette) transporter that regulates intracellular lipid metabolism., PMID:15810880

Rab3D and actin reveal distinct lamellar body subpopulations in alveolar epithelial type II cells., PMID:12933357

An ATP-binding cassette transporter is a major glycoprotein of sea urchin sperm membranes., PMID:12193601

Identification of LBM180, a lamellar body limiting membrane protein of alveolar type II cells, as the ABC transporter protein ABCA3., PMID:11940594

ABCA3 is a lamellar body membrane protein in human lung alveolar type II cells., PMID:11718719

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