Human Rheumatoid Factor IgM Antibody (2A2)

Catalog No.

RHK25303

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgM

Clonality

Monoclonal

Target

Rheumatoid Factor, RF, rheumatoid factors (RFs)

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein L purified from cell culture supernatant.

Applications

Rheumatoid Factor (RF) Reference Standard

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Clone ID

2A2

Additive Value of Rheumatoid Factor Isotypes in Sjögren's Syndrome Patients with Joint Complaints of Different Etiologies-Can Rheumatoid Factor IgA Serve as an Early, Poor Prognostic Biomarker Candidate?, PMID:40429937

Impact of rheumatoid factors on the function of therapeutic monoclonals specific for PD-1/PD-L1., PMID:40411581

A Tool to Eliminate IgM Immunoassay Interference., PMID:40216709

Serum Proteomic Signatures Before the Diagnosis of Rheumatoid Arthritis: Evolving Biologic Pathways and Specific Periods of Disease Development., PMID:40189919

Peripheral blood immunoprofiling in patients with polypropylene mesh implants for hernia repair: a single-center cohort study., PMID:40167840

The role of autoantibodies in post-chikungunya viral arthritis disease severity., PMID:40042325

Rheumatoid arthritis-associated rheumatoid factors post-COVID-19., PMID:40018049

Predictors of arthritis development in individuals at risk of rheumatoid arthritis: a 5-year follow-up study from a large cohort., PMID:39956700

Distinct clinical outcomes based on multiple serum cytokine and chemokine profiles rather than autoantibody profiles and ultrasound findings in rheumatoid arthritis: a prospective ultrasound cohort study., PMID:39863304

What is rheumatoid factor? From screening to personalized management., PMID:39792161

Rheumatoid factor levels indicate cryoglobulinemia severity in hepatitis B e antigen-negative hepatitis B virus carriers: a 7-year prospective cohort study., PMID:39699792

Anti-Modified Peptide Antibodies (AMPAs) in Rheumatoid Arthritis: Study of the Diagnostic Value of Citrullinated, Homocitrullinated, and Acetylated Fibrin/Filaggrin Chimeric Peptides., PMID:39594151

How Were the Elderly RA Patients Doing Over the Past Year?-A Post Hoc Analysis for Telephone Based Following Up to RA Patients in Zunyi China., PMID:39583861

High serum levels of CXCL13 predict lower response to csDMARDs in both ACPA-positive and ACPA-negative early rheumatoid arthritis., PMID:39468732

Pseudo-Elevation of Anti Double Stranded DNA IgG Antibody Caused by Rheumatoid Factor., PMID:39193970

Next-generation rheumatoid factor assay provides improved predictive power for the development of arthritis in patients at risk., PMID:39164049

Autoantibodies Serum Level and 10-Year Risk of Fractures Evaluated by FRAX® Tool in Rheumatoid Arthritis Patients., PMID:39045423

Distinct groups of autoantigens as drivers of ocular adnexal MALT lymphoma pathogenesis., PMID:38977312

Incidence of seropositive and seronegative rheumatoid arthritis in Denmark: a nationwide population-based study., PMID:38975830

The prognostic value of IgA anti-citrullinated protein antibodies and rheumatoid factor in an early arthritis population with a treat-to-target approach., PMID:38960995

[High expression of anti-β2 glycoprotein I (β2GPI) autoantibody exacerbates inflammation and immune dysfunction in connective tissue disease]., PMID:38952093

Autoantibody-positivity before and seroconversion during treatment with anti-PD-1 is associated with immune-related adverse events in patients with melanoma., PMID:38945553

Increased Rheumatoid Factor production in patients with severe COVID-19., PMID:38604077

Natural Autoantibodies in Biologic-Treated Rheumatoid Arthritis and Ankylosing Spondylitis Patients: Associations with Vascular Pathophysiology., PMID:38542402

Exploring the Link between Hydrodynamic Size and Immunoglobulins of Circulating Immune Complexes in Rheumatoid Arthritis Patients., PMID:38542112

Predicting risk of subsequent pregnancy loss among women with recurrent pregnancy loss: An immunological factor-based multivariable model., PMID:38514448

Longitudinal rheumatoid factor autoantibody responses after SARS-CoV-2 vaccination or infection., PMID:38487524

Elevated expression of Toll-like receptor 7 and its correlation with clinical features in patients with primary Sjögren's syndrome., PMID:38439071

Prognostic value of serum protein electrophoresis constituents for arthritis development in anti-citrullinated protein antibody-positive patients with musculoskeletal pain., PMID:38214468

[Clinical and immunological features of primary Sjögren's syndrome patients with positive anti-centromere protein B antibody]., PMID:38101794

In early rheumatoid arthritis, anticitrullinated peptide antibodies associate with low number of affected joints and rheumatoid factor associates with systemic inflammation., PMID:38049984

Association between toxoplasmosis and autoimmune rheumatic diseases in Egyptian patients., PMID:37945182

Are the cut-offs of the rheumatoid factor and anti-cyclic citrullinated peptide antibody different to distinguish rheumatoid arthritis from their primary differential diagnoses?, PMID:37933209

A novel highly specific biotinylated MAC-ELISA for detection of anti-SARS-CoV-2 nucleocapsid antigen IgM antibodies during the acute phase of COVID-19., PMID:37930615

Assessment of anti-malondialdehyde-acetaldehyde antibody frequencies in rheumatoid arthritis with new data from two independent cohorts, meta-analysis, and meta-regression., PMID:37798800

IgM antibodies against acetylated proteins as a possible starting point of the anti-modified protein antibody response in rheumatoid arthritis., PMID:37788903

Interleukin 4-driven reversal of self-reactive B cell anergy contributes to the pathogenesis of systemic lupus erythematosus., PMID:37567607

Clinical features and genetic biomarkers associated with different phenotypes of systemic lupus erythematosus in Paraguayan patients., PMID:37462131

Can Bariatric Surgery Help to Prevent Autoimmunity?, PMID:37442664

Testing for isotypes does not help differentiating rheumatoid arthritis from other rheumatoid factor positive diseases., PMID:37322352

Serological markers of rheumatoid arthritis in patients with primary biliary cholangitis and the vice versa: A Tunisian study., PMID:37269587

Natural autoimmunity in oligoarticular juvenile idiopathic arthritis., PMID:37138302

Sex Difference in Primary Sjögren Syndrome: A Medical Records Review Study., PMID:37068269

Rheumatoid factor autoantibody repertoire profiling reveals distinct binding epitopes in health and autoimmunity., PMID:37055152

Lack of comparability of immunoassays for rheumatoid factor isotypes., PMID:37027892

Radiographic airway abnormalities in untreated early rheumatoid arthritis are associated with peripheral neutrophil activation., PMID:36941690

Autoimmune markers and vascular immune deposits in Finkelstein-Seidlmayer vasculitis: Systematic literature review., PMID:36822150

Serum antibodies to periodontal pathogens prior to rheumatoid arthritis diagnosis: A case-control study., PMID:36812865

Challenges in the diagnosis of hypervitaminemia B12. Interference by immunocomplexes., PMID:36805891

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