Catalog No.
EMD75701
Expression system
Mammalian Cells
Species
Mus musculus (Mouse)
Protein length
Met1-Glu355
Predicted molecular weight
40.45 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P27931
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Interleukin-1 receptor type 2, IL-1R-2, IL-1RT-2, IL-1RT2, CD121 antigen-like family member B, IL-1 type II receptor, Interleukin-1 receptor beta, IL-1R-beta, Interleukin-1 receptor type II, CD121b, Interleukin-1 receptor type 2, membrane form, mIL-1R2, mIL-1RII, Interleukin-1 receptor type 2, soluble form, sIL-1R2, sIL-1RII, Il1r2, Il-1r2, Il1rb
CD121b-positive neutrophils predict immunosuppression in septic shock., PMID:40230851
Monocyte-macrophage membrane expression of IL-1R2 is a severity biomarker in sepsis., PMID:40204720
Interleukin-1 family cytokines and soluble receptors in hidradenitis suppurativa., PMID:39278731
Negative regulator IL-1 receptor 2 (IL-1R2) and its roles in immune regulation of autoimmune diseases., PMID:38850793
Il1r2 and Tnfrsf12a in transcranial magnetic stimulation effect of ischemic stroke via bioinformatics analysis., PMID:38277520
IL1R2 promotes retinal angiogenesis to participate in retinopathy of prematurity by activating the HIF1α/PFKFB3 pathway., PMID:38097102
IL1R2 Gene Expression Is Downregulated in Obesity- Associated Asthma., PMID:37669081
IL1R2 is a Novel Prognostic Biomarker for Lung Adenocarcinoma., PMID:37078353
Single-cell analysis reveals novel clonally expanded monocytes associated with IL1β-IL1R2 pair in acute inflammatory demyelinating polyneuropathy., PMID:37041166
Over-expression of IL1R2 in PBMCs of Patients with Coronary Artery Disease and Its Clinical Significance., PMID:35943312
Negative Regulation of the IL-1 System by IL-1R2 and IL-1R8: Relevance in Pathophysiology and Disease., PMID:35211118
Cardiomyocyte IL-1R2 protects heart from ischemia/reperfusion injury by attenuating IL-17RA-mediated cardiomyocyte apoptosis., PMID:35087030
The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with sudden sensorineural hearing loss in a Taiwanese population: a case control study., PMID:34865658
IL1R2 polymorphisms and their interaction are associated with osteoporosis susceptibility in the Chinese Han population., PMID:34664761
Influence of Sociodemographic Characteristics and Inflammation-Related Gene Variants on the Comfort Level of Caregivers of Patients With Head and Neck Cancer., PMID:34636689
Influence of IL1B (rs16944) and IL1R2 (rs4141134) polymorphisms on aggressiveness and prognosis of cutaneous melanoma., PMID:34284461
Association of ITPKB, IL1R2 and COQ7 with Parkinson's disease in Taiwan., PMID:34244037
Potential role of a three-gene signature in predicting diagnosis in patients with myocardial infarction., PMID:34130601
Cytokine Signature of Dengue Patients at Different Severity of the Disease., PMID:33809042
IL-1R2 expression in human gastric cancer and its clinical significance., PMID:33704402
Induction of the IL-1RII decoy receptor by NFAT/FOXP3 blocks IL-1β-dependent response of Th17 cells., PMID:33507149
LncRNA A2M-AS1 lessens the injury of cardiomyocytes caused by hypoxia and reoxygenation via regulating IL1R2., PMID:33057899
Platelet concentrate and type II IL-1 receptor are risk factors for allergic transfusion reactions in children., PMID:32727543
Association of ZNF184, IL1R2, LRRK2, ITPKB, and PARK16 with sporadic Parkinson's disease in Eastern China., PMID:32682840
Cell surface IL-1α trafficking is specifically inhibited by interferon-γ, and associates with the membrane via IL-1R2 and GPI anchors., PMID:32447774
Association of IL1R2 rs34043159 with sporadic Alzheimer's disease in southern Han Chinese., PMID:32402117
The association of genetic polymorphisms in interleukin-1 receptors type 1 and type 2 with age-related hearing impairment in a Taiwanese population: a case control study., PMID:32252823
Transcriptome Meta-Analysis Deciphers a Dysregulation in Immune Response-Associated Gene Signatures during Sepsis., PMID:31817302
Commensal microbiota drive the functional diversification of colon macrophages., PMID:31772323
IL1R2 Polymorphisms are Associated with Increased Risk of Esophageal Cancer., PMID:31744444
The Relationship Between Cytokine Production, CSF2RA, and IL1R2 Expression in Mammary Adenocarcinoma, Tumor Histopathological Parameters, and Lymph Node Metastasis., PMID:31635541
Genetic polymorphisms in IL1R1 and IL1R2 are associated with susceptibility to thyroid cancer in the Chinese Han population., PMID:31021479
Influence of IL-1R2 polymorphisms on endometrial cancer susceptibility in the Chinese Han population., PMID:30895748
Association between IL-1R2 polymorphisms and lung cancer risk in the Chinese Han population: A case-control study., PMID:30895747
Association between the IL1R2 rs2072472 polymorphism and high-altitude pulmonary edema risk., PMID:30672138
Impact of IL1R1 and IL1R2 gene polymorphisms on risk of osteonecrosis of the femoral head from a case-control study., PMID:30623603
The impact of genetic variants in IL1R2 on cervical cancer risk among Uygur females from China: A case-control study., PMID:30460760
IL1R1 and IL1R2 polymorphisms were associated with tuberculosis risk: A pilot study., PMID:30256493
Regulation of IL-1 signaling by the decoy receptor IL-1R2., PMID:30109367
Screening genes associated with elevated neutrophil‑to‑lymphocyte ratio in chronic heart failure., PMID:29901123
Soluble IL-1 receptor 2 is associated with left ventricular remodelling in patients with ST-elevation myocardial infarction., PMID:29853279
A large lung gene expression study identifying IL1B as a novel player in airway inflammation in COPD airway epithelial cells., PMID:29616282
Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8., PMID:29247989
Integrative transcriptomic analysis reveals key drivers of acute peanut allergic reactions., PMID:29203772
IL-1 family cytokines and receptors in IgG4-related disease., PMID:28823915
Lower levels of interleukin-1β gene expression are associated with impaired Langerhans' cell migration in aged human skin., PMID:28777886
Systematic identification of key genes and pathways in the development of invasive cervical cancer., PMID:28341182
Airway gene expression of IL-1 pathway mediators predicts exacerbation risk in obstructive airway disease., PMID:28223794
Interleukin-1 Receptor 2: A New Biomarker for Sepsis Diagnosis and Gram-Negative/Gram-Positive Bacterial Differentiation., PMID:27984536
Association of six CpG-SNPs in the inflammation-related genes with coronary heart disease., PMID:27461004
For research use only. Not for human or drug use.
