Anti-PCSK1 Polyclonal Antibody

Catalog No.

PHD81701

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human PCSK1 (Ala500-Asn753).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

PC1,PCSK1,Neuroendocrine convertase 1,Prohormone convertase 1,Proprotein convertase 1,NEC 1,NEC1

Purification

Purified by antigen affinity column.

Accession

P29120

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Low concentration IL-1β promotes islet amyloid formation by increasing hIAPP release from humanised mouse islets in vitro., PMID:32728889

Initial Real-World Experience With PCSK-9 Inhibitors in Current Indications for Reimbursement in Spain., PMID:31103377

Human 'brite/beige' adipocytes develop from capillary networks, and their implantation improves metabolic homeostasis in mice., PMID:26808348

Association of adenovirus 36 infection with obesity-related gene variants in adolescents., PMID:26680480

The prohormone processing enzyme PC3 is a lipid raft-associated transmembrane protein., PMID:12950171

Immunocytochemical localization of prohormone convertases PC1 and PC2 in the mouse thyroid gland and respiratory tract., PMID:12070269

Isolation and characterization of VGF peptides in rat brain. Role of PC1/3 and PC2 in the maturation of VGF precursor., PMID:12065665

Activation and routing of membrane-tethered prohormone convertases 1 and 2., PMID:10455138

Proprotein convertase PC1/3-related peptides are potent slow tight-binding inhibitors of murine PC1/3 and Hfurin., PMID:9813073

Obesity and impaired prohormone processing associated with mutations in the human prohormone convertase 1 gene., PMID:9207799

Proteolytic processing of pro-opiomelanocortin occurs in acidifying secretory granules of AtT-20 cells., PMID:9071324

Chromogranin A processing and secretion: specific role of endogenous and exogenous prohormone convertases in the regulated secretory pathway., PMID:8690787

Application of the multiple antigenic peptides (MAP) strategy to the production of prohormone convertases antibodies: synthesis, characterization and use of 8-branched immunogenic peptides., PMID:9223018

Furin, PC1/3, and/or PC6A process rabbit, but not human, pro-lactase-phlorizin hydrolase to the 180-kDa intermediate., PMID:7592752

Processing of mouse proglucagon by recombinant prohormone convertase 1 and immunopurified prohormone convertase 2 in vitro., PMID:7730317

Release of the prohormone convertase PC1 from AtT-20 cells., PMID:8413860

Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones., PMID:1435788

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