Catalog No.
PHD71301
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human PTBP1 (Met1-Ile531).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
PTB,Polypyrimidine tract-binding protein 1,57 kDa RNA-binding protein PPTB-1,PTBP1,Heterogeneous nuclear ribonucleoprotein I,hnRNP I
Purification
Purified by antigen affinity column.
Accession
P26599
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
PTBP1 protects Y RNA from cleavage leading to its apoptosis-specific degradation., PMID:38997262
Circular RNA circIL21R promotes cervical cancer cells proliferation and migration by sponging the miR-1205/PTBP1 axis., PMID:38726271
An in vitro-transcribed circular RNA targets the mitochondrial inner membrane cardiolipin to ablate EIF4G2+/PTBP1+ pan-adenocarcinoma., PMID:37845485
LncRNA FIRRE stimulates PTBP1-induced Smurf2 decay, stabilizes B-cell receptor, and promotes the development of diffuse large B-cell lymphoma., PMID:35416325
Endothelial cell-specific expression of serine/threonine kinase 11 modulates dendritic cell differentiation., PMID:35115536
Essential requirement for polypyrimidine tract binding proteins 1 and 3 in the maturation and maintenance of mature B cells in mice., PMID:34214192
lncRNA ZNF649-AS1 Induces Trastuzumab Resistance by Promoting ATG5 Expression and Autophagy., PMID:32735773
Long noncoding RNA ANCR inhibits the differentiation of mesenchymal stem cells toward definitive endoderm by facilitating the association of PTBP1 with ID2., PMID:31235689
RNA-binding protein Ptbp1 is essential for BCR-mediated antibody production., PMID:30476084
The RNA-binding protein PTBP1 is necessary for B cell selection in germinal centers., PMID:29358707
Automated fluorescent miscroscopic image analysis of PTBP1 expression in glioma., PMID:28282372
Quantitative validation of anti-PTBP1 antibody for diagnostic neuropathology use: Image analysis approach., PMID:28024117
PTBP-dependent PSD-95 and CamKIIα alternative splicing in the lens., PMID:25540577
Hepatitis B virus core protein inhibits Fas-mediated apoptosis of hepatoma cells via regulation of mFas/FasL and sFas expression., PMID:25466893
Brain metastasis is predetermined in early stages of cutaneous melanoma by CD44v6 expression through epigenetic regulation of the spliceosome., PMID:25169209
For research use only. Not for human or drug use.
