Catalog No.
PHD67201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human CD95/FAS (Gln26-Asn173).
Applications
ELISA, IHC, WB
Recommended Dilution
| Application |
Dilution |
| ELISA |
1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000 |
Target
APT1,TNFRSF6,FAS1,FASLG receptor,CD95,Apo-1 antigen,Tumor necrosis factor receptor superfamily member 6,FAS,Apoptosis-mediating surface antigen FAS
Purification
Purified by antigen affinity column.
Accession
P25445
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Note
For research use only.
The murine meninges acquire lymphoid tissue properties and harbour autoreactive B cells during chronic Trypanosoma brucei infection., PMID:37983289
EGF-Receptor against Amphiregulin (AREG) Influences Costimulatory Molecules on Monocytes and T Cells and Modulates T-Cell Responses., PMID:38046264
NGAL Mediates Anaplastic Thyroid Carcinoma Cells Survival Through FAS/CD95 Inhibition., PMID:38091978
Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma., PMID:38129580
Immune Control in Repeated Babesia microti Infection in a Patient With B-Cell Deficiency., PMID:38213635
Membrane-bound CD95 ligand modulates CD19-mediated B cell receptor signaling and EBV activation., PMID:38299675
Cyclizine induces cytotoxicity and apoptosis in macrophages through the extrinsic and intrinsic apoptotic pathways., PMID:38314619
Early allogeneic immune modulation after establishment of donor hematopoietic cell-induced mixed chimerism in a nonhuman primate kidney transplant model., PMID:38318170
[Lung pathology in children with a long-term novel coronavirus infection COVID-19]., PMID:38319270
Discoidin domain receptor 2 signaling through PIK3C2α in fibroblasts promotes lung fibrosis., PMID:38332727
Effect of Temperature on the Development of Stages of Spermatogenesis and the Functionality of Sertoli Cells In Vitro., PMID:38396838
CD40 stimulation via CD40 ligand enhances adenovirus-mediated tumour immunogenicity including 'find-me', 'eat-me', and 'kill-me' signalling., PMID:38494863
Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model., PMID:38515743
Advancements in γδT cell engineering: paving the way for enhanced cancer immunotherapy., PMID:38576617
Early B cell transcriptomic markers of measles-specific humoral immunity following a 3rd dose of MMR vaccine., PMID:38633249
Molecular Hydrogen as a Promising Therapy Could Be Linked With Increased Resting Treg Cells or Decreased Fas+ T Cell Subsets in a IgG4-PF-ILD Patient: A Case Report., PMID:38688598
Scattered Crypt Intestinal Epithelial Cell Apoptosis Induces Necrotizing Enterocolitis Via Intricate Mechanisms., PMID:38788898
Peripheral CX3CR1+ T cells combined with PD-1 blockade therapy potentiates the anti-tumor efficacy for lung cancer., PMID:38798746
Molecular signatures in prion disease: altered death receptor pathways in a mouse model., PMID:38802941
Interleukin-10 induces TNF-driven apoptosis and ROS production in salivary gland cancer cells., PMID:38882335
Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:38895251
Adaptive post-COVID-19 immune response in female subjects of the Russian arctic region., PMID:38989746
Nematode Galectin Inhibits Basophilic Leukaemia RBL-2H3 Cells Apoptosis in IgE-Mediated Activation., PMID:39000527
Features of the immune system and levels of blood transport components in residents of the arctic of the Russian Federation., PMID:39032081
The development of anti-PD-1 antibody-induced spinal cord injury in bone marrow transplant C57BL/6 Rag1-/- mouse model., PMID:39115961
Diversity of Memory CD8+ T Cells in Tumor-Draining Lymph Nodes from Patients with Bladder Cancer., PMID:39184818
Immunological insights: assessing immune parameters in medical professionals exposed to SARS-CoV-2., PMID:39187767
A Novel Tetravalent CD95/Fas Fusion Protein With Superior CD95L/FasL Antagonism., PMID:39219154
Transient-resting culture after activation enhances the generation of CD8+ stem cell-like memory T cells from peripheral blood mononuclear cells., PMID:39357466
Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:39466842
In vivo analysis of CRISPR-edited germinal center murine B cells., PMID:39483469
Arthritis progressors have a decreased frequency of circulating autoreactive T cells during the at-risk phase of rheumatoid arthritis., PMID:39557489
The Role of TNF Receptor-Associated Factor 5 in the Formation of Germinal Centers by B Cells During the Primary Phase of the Immune Response in Mice., PMID:39596396
Cervical Cancer Cells Use the CD95 and IL-2 Pathways to Promote Their Proliferation and Survival., PMID:39766250
Identification of B Cell Subpopulations with Pro- and Anti-Tumorigenic Properties in an Immunocompetent Mouse Model of Head and Neck Squamous Cell Carcinoma., PMID:39791721
An engineered palivizumab IgG2 subclass for synthetic gp130 and fas-mediated signaling., PMID:39828098
[Effects of occupational lead exposure on the indicators of immune function of workers]., PMID:39909595
Neutralizing IL-15 Inhibits Tissue-Damaging Immune Response in Ex Vivo Cultured Untreated Celiac Intestinal Mucosa., PMID:39937025
Spatially Resolved, Multiregion Proteomics for Prediction of Immunotherapy Outcome in Deficient Mismatch Repair Metastatic Colorectal Cancer., PMID:39969975
Deep profiling of B cells responding to various pathogens uncovers compartments in IgG memory B cell and antibody-secreting lineages., PMID:39970201
T cell receptor usage and epitope specificity amongst CD8+ and CD4+ SARS-CoV-2-specific T cells., PMID:40092978
Coordination of Neutrophil and Apoptosis-Inducing Ligand in Inflammatory Diseases., PMID:40099000
Distinct type 1 immune networks underlie the severity of restrictive lung disease after COVID-19., PMID:40140496
CD73low B-cell phenotypes and distinct cytokine profiles in patients with active anti-Jo-1 antibody positive idiopathic inflammatory myopathies., PMID:40210261
Dengue Viral Infection Induces Alteration of CD95 Expression in B Cell Subsets with Potential Involvement of Dengue Viral Non-Structural Protein 1., PMID:40284984
Single molecule recognition of CD95 receptors on the surface of HepG2 cells under the curcumin., PMID:40300310
FAS mediates apoptosis, inflammation, and treatment of pathogen infection., PMID:40330016
Actionable heterogeneity of hepatocellular carcinoma therapy-induced senescence., PMID:40374812
Circulating immunoregulatory B cell and autoreactive antibody profiles predict lack of toxicity to anti-PD-1 checkpoint inhibitor treatment in advanced melanoma., PMID:40449958
Phosphatidylglucoside regulates apoptosis of human neutrophilic lineage cells., PMID:40496860