Catalog No.
                        EVV15201
                        
                                            
                                            
                                            Expression system
                        
                        Mammalian Cells                        
                                                
                                            Species
                        
                        Epstein-Barr virus (strain B95-8) (HHV-4) (Human herpesvirus 4)                        
                                                
                                            Protein length
                        
                        Met1-Ser475                        
                                                
                                            Predicted molecular weight
                        
                        53 kDa                        
                                                
                                            Nature
                        
                        Recombinant                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Endotoxin level
                        
                        Please contact with the lab for this information.                        
                                                
                                            Purity
                        
                        >90% as determined by SDS-PAGE.                        
                                                
                                            
                                            Accession
                        
                        P03200                        
                                                
                                            
                                            Applications
                        
                        ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress                        
                                                
                                            Form
                        
                        Lyophilized                        
                                                
                                            Storage buffer
                        
                        Lyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.                        
                                                
                                            Reconstitution
                        
                        Reconstitute in sterile water for a stock solution.                        
                                                
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            
                                            Shipping
                        
                        In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.                        
                                                
                                            Stability and Storage
                        
                        Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.                        
                                                
                                            
                                            
                                                Alternative Names
                            Envelope glycoprotein GP350, Membrane antigen, MA, BLLF1
                            
                                                    
                                            
                                            
                                        
                 
                
                
                                            Infectious Epstein-Barr virus lacking major glycoprotein BLLF1 (gp350/220) demonstrates the existence of additional viral ligands. PMID: 11024143
                                            Evaluation of the new Abbott Real-Time EBV assay: fully automated quantification of EBV in whole blood by targeting BLLF1. PMID: 30777343
                                            The SWI/SNF Chromatin Regulator BRG1 Modulates the Transcriptional Regulatory Activity of the Epstein-Barr Virus DNA Polymerase Processivity Factor BMRF1. PMID: 28228591
                                            Epstein-Barr virus mRNA export factor EB2 is essential for intranuclear capsid assembly and production of gp350. PMID: 16254345
                                            [Expression of Epstein-Barr virus genes in EBV-associated gastric carcinoma]. PMID: 15248912
                                            Survey of Epstein Barr virus (EBV) immunogenic proteins and their epitopes: implications for vaccine preparation. PMID: 25164057
                                            Radiation-induced Epstein-Barr virus reactivation in gastric cancer cells with latent EBV infection. PMID: 28675108
                                            The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD. PMID: 31462557
                                            Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy. PMID: 22590638
                                            Characterization of Epstein-Barr virus gp350/220 gene variants in virus isolates from gastric carcinoma and nasopharyngeal carcinoma. PMID: 22038027
                                            Role of the TSG101 gene in Epstein-Barr virus late gene transcription. PMID: 17182691
                                            Expression of Epstein-Barr virus genes in EBV-associated gastric carcinomas. PMID: 15655811
                                            Quantitation of Epstein-Barr virus mRNA using reverse transcription and real-time PCR. PMID: 15484273
                                            Qualitative analysis of the expression of Epstein-Barr virus lytic genes in nasopharyngeal carcinoma biopsies. PMID: 7782768
                                            Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding. PMID: 19889766
                                            Epstein-Barr virus burden in Hodgkin's disease is related to latent membrane protein gene expression but not to active viral replication. PMID: 1384793
                                            Aberrant Epstein-Barr viral infection in systemic lupus erythematosus. PMID: 19167523
                                            Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population. PMID: 25933165
                                            [Epstein-Barr virus replication in Hodgkin disease]. PMID: 7894116
                                            Evidence of lytic infection of Epstein-Barr virus (EBV) in EBV-positive gastric carcinoma. PMID: 11793387
                                            Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus. PMID: 22623769
                                            Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins. PMID: 16549597
                                            Demonstration of Epstein-Barr virus replication in Reed-Sternberg cells of Hodgkin's disease. PMID: 8393354
                                            Real-time quantitative PCR for assessment of antiviral drug effects against Epstein-Barr virus replication and EBV late mRNA expression. PMID: 17368820
                                            Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins. PMID: 22458933
                                            Transcriptional expression of the viral genome in the Epstein-Barr virus-induced tamarin lymphoma and the corresponding lymphoblastoid tumour lines. PMID: 1335674
                                            Truncated versions of the two major Epstein-Barr viral glycoproteins (gp250/350) are secreted by recombinant Chinese hamster ovary cells. PMID: 2826297
                                            Expression of Epstein-Barr virus membrane antigen gp350/220 in E. coli and in insect cells. PMID: 1329330
                                            A Comparative Genomic Analysis of Epstein-Barr Virus Strains with a Focus on EBV2 Variability., PMID:40141350
                                            The Epstein-Barr Virus BMRF1 Protein Activates Transcription and Inhibits the DNA Damage Response by Binding NuRD., PMID:31462557
                                            Evaluation of the new Abbott Real-Time EBV assay: fully automated quantification of EBV in whole blood by targeting BLLF1., PMID:30777343
                                            Epstein-Barr virus lytic cycle involvement in diffuse large B cell lymphoma., PMID:28707331
                                            Radiation-induced Epstein-Barr virus reactivation in gastric cancer cells with latent EBV infection., PMID:28675108
                                            The SWI/SNF Chromatin Regulator BRG1 Modulates the Transcriptional Regulatory Activity of the Epstein-Barr Virus DNA Polymerase Processivity Factor BMRF1., PMID:28228591
                                            Epstein-Barr virus genetic variation in lymphoblastoid cell lines derived from Kenyan pediatric population., PMID:25933165
                                            Survey of Epstein Barr virus (EBV) immunogenic proteins and their epitopes: implications for vaccine preparation., PMID:25164057
                                            Epstein-barr virus infected gastric adenocarcinoma expresses latent and lytic viral transcripts and has a distinct human gene expression profile., PMID:22929309
                                            Shutoff of BZLF1 gene expression is necessary for immortalization of primary B cells by Epstein-Barr virus., PMID:22623769
                                            Genomic sequencing and comparative analysis of Epstein-Barr virus genome isolated from primary nasopharyngeal carcinoma biopsy., PMID:22590638
                                            Methylation profiling of Epstein-Barr virus immediate-early gene promoters, BZLF1 and BRLF1 in tumors of epithelial, NK- and B-cell origins., PMID:22458933
                                            Expression of BamHI-A Rightward Transcripts in Epstein-Barr Virus-Associated Gastric Cancers., PMID:22247711
                                            Characterization of Epstein-Barr virus gp350/220 gene variants in virus isolates from gastric carcinoma and nasopharyngeal carcinoma., PMID:22038027
                                            Epstein-Barr viruses that express a CD21 antibody provide evidence that gp350's functions extend beyond B-cell surface binding., PMID:19889766
                                            Aberrant Epstein-Barr viral infection in systemic lupus erythematosus., PMID:19167523
                                            Role of the TSG101 gene in Epstein-Barr virus late gene transcription., PMID:17182691
                                            Control of Epstein-Barr virus infection in vitro by T helper cells specific for virion glycoproteins., PMID:16549597
                                            Epstein-Barr virus mRNA export factor EB2 is essential for intranuclear capsid assembly and production of gp350., PMID:16254345
                                            Expression of Epstein-Barr virus genes in EBV-associated gastric carcinomas., PMID:15655811
                                            [Expression of Epstein-Barr virus genes in EBV-associated gastric carcinoma]., PMID:15248912
                                            [Expression of Epstein-Barr virus membrane antigen induces lymphoma in transgenic mice]., PMID:11798890
                                            Evidence of lytic infection of Epstein-Barr virus (EBV) in EBV-positive gastric carcinoma., PMID:11793387
                                            Infectious Epstein-Barr virus lacking major glycoprotein BLLF1 (gp350/220) demonstrates the existence of additional viral ligands., PMID:11024143
                                            Qualitative analysis of the expression of Epstein-Barr virus lytic genes in nasopharyngeal carcinoma biopsies., PMID:7782768
                                            [Epstein-Barr virus replication in Hodgkin disease]., PMID:7894116
                                            Demonstration of Epstein-Barr virus replication in Reed-Sternberg cells of Hodgkin's disease., PMID:8393354
                                            Epstein-Barr virus burden in Hodgkin's disease is related to latent membrane protein gene expression but not to active viral replication., PMID:1384793
                                            Expression of Epstein-Barr virus membrane antigen gp350/220 in E. coli and in insect cells., PMID:1329330
                                            Truncated versions of the two major Epstein-Barr viral glycoproteins (gp250/350) are secreted by recombinant Chinese hamster ovary cells., PMID:2826297