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Anti-CYP3A7 Polyclonal Antibody

Catalog #:   PHD62701 Specific References (24) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P24462
Overview

Catalog No.

PHD62701

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CYP3A7 (Pro344-Asp497).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

CYP3A7,CYPIIIA7,P450HLp2,Cytochrome P450 3A7,Cytochrome P450-HFLA

Purification

Purified by antigen affinity column.

Accession

P24462

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CYP3A7 antibody (PHD62701) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 20 kDa
    Observed MW: 20 kDa
References

[Effects of pargyline on histone methylation in promoter and enhancer regions and transcription of CYP3A4/3A7]., PMID:29911787

Indirect protein quantification of drug-transforming enzymes using peptide group-specific immunoaffinity enrichment and mass spectrometry., PMID:25737130

In vitro characterization of the oxidation of a pyridinium metabolite of haloperidol by human placenta: the effect of smoking., PMID:23106957

Hepatic differentiation of human embryonic stem cells is promoted by three-dimensional dynamic perfusion culture conditions., PMID:21210720

Distinction between human cytochrome P450 (CYP) isoforms and identification of new phosphorylation sites by mass spectrometry., PMID:18828626

Localization and mRNA expression of CYP3A and P-glycoprotein in human duodenum as a function of age., PMID:16049125

CYP3A7 protein expression is high in a fraction of adult human livers and partially associated with the CYP3A7*1C allele., PMID:16041241

Variability of CYP3A7 expression in human fetal liver., PMID:15845858

Differential enantioselectivity and product-dependent activation and inhibition in metabolism of verapamil by human CYP3As., PMID:14744940

Developmental expression of the major human hepatic CYP3A enzymes., PMID:12975492

Cytochrome P450 4A11 expression in human keratinocytes: effects of ultraviolet irradiation., PMID:11736898

Role of a potent inhibitory monoclonal antibody to cytochrome P-450 3A4 in assessment of human drug metabolism., PMID:10525096

Inhibitory anti-CYP3A4 peptide antibody: mapping of inhibitory epitope and specificity toward other CYP3A isoforms., PMID:9929498

Regulation of CYP1A and CYP3A mRNAs by ascorbic acid in guinea pigs., PMID:9434738

Expression and localization of CYP3A4 and CYP3A5 in human lung., PMID:9070608

Selective expression of CYP3A5 and not CYP3A4 in human blood., PMID:8946469

Hierarchical cluster analysis of environmental pollutants through P450 induction in cultured hepatic cells., PMID:8812189

Detection of cytochrome P450 gene expression in human placenta in first trimester of pregnancy., PMID:8694864

Bimodal distribution of renal cytochrome P450 3A activity in humans., PMID:8700118

Functional cytochrome P4503A isoforms in human embryonic tissues: expression during organogenesis., PMID:7969081

CYP3A gene expression in human gut epithelium., PMID:7894497

Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta., PMID:8349787

Immunochemical characterization and toxicological significance of P-450HFLb purified from human fetal livers., PMID:1420280

[Cytochrome P-450 in human fetal liver. Properties of P-450 HFLa,a form of cytochrome P-450 in human fetal livers]., PMID:2066864

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

Contact Information

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Distributor list

For research use only. Not for human or drug use.

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Anti-CYP3A7 Polyclonal Antibody [PHD62701]
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