Catalog No.
YVV24801
Expression system
E. coli
Species
Lake Victoria marburgvirus (strain Musoke-80) (MARV) (Marburg virus (strain Kenya/Musoke/1980))
Protein length
Met1-Leu241
Predicted molecular weight
29.42 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
P35256
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Membrane-associated protein VP24, Marburg VP24, mVP24, VP24
From protein to immunology: comprehensive insights into Marburg virus vaccines, mechanism, and application., PMID:40025302
Longitudinal proteome-wide antibody profiling in Marburg virus survivors identifies wing domain immunogen for vaccine design., PMID:39285186
Designing a novel and combinatorial multi-antigenic epitope-based vaccine "MarVax" against Marburg virus-a reverse vaccinology and immunoinformatics approach., PMID:38012426
VP24 matrix proteins of eight filoviruses downregulate innate immune response by inhibiting the interferon-induced pathway., PMID:37647113
Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene., PMID:35997284
Mining of Marburg Virus Proteome for Designing an Epitope-Based Vaccine., PMID:35911751
Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation., PMID:35069519
Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways., PMID:32295912
Small Molecule Compounds That Inhibit Antioxidant Response Gene Expression in an Inducer-Dependent Manner., PMID:31899866
Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions., PMID:28122983
Novel activities by ebolavirus and marburgvirus interferon antagonists revealed using a standardized in vitro reporter system., PMID:27930961
Dimerization Controls Marburg Virus VP24-dependent Modulation of Host Antioxidative Stress Responses., PMID:27497688
Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection., PMID:26962215
Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells., PMID:26255028
Marburg Virus VP24 Protein Relieves Suppression of the NF-κB Pathway Through Interaction With Kelch-like ECH-Associated Protein 1., PMID:25926686
Marburgvirus hijacks nrf2-dependent pathway by targeting nrf2-negative regulator keap1., PMID:24630992
The Marburg virus VP24 protein interacts with Keap1 to activate the cytoprotective antioxidant response pathway., PMID:24630991
Advances in virus-like particle vaccines for filoviruses., PMID:21987741
Filoviral immune evasion mechanisms., PMID:21994800
Marburg virus evades interferon responses by a mechanism distinct from ebola virus., PMID:20084112
Establishment and application of an infectious virus-like particle system for Marburg virus., PMID:20071483
Evasion of the interferon-mediated antiviral response by filoviruses., PMID:21994610
Evasion of interferon responses by Ebola and Marburg viruses., PMID:19694547
VP24 of Marburg virus influences formation of infectious particles., PMID:16227263
Filovirus budding., PMID:15567496
For research use only. Not for human or drug use.
