Catalog No.
PHD59401
Species reactivity
Human, Mouse, Rat
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human BDNF (Arg128-Arg247).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
ProBDNF,Abrineurin,Brain-derived neurotrophic factor,BDNF
Purification
Purified by antigen affinity column.
Accession
P23560
Applications
ELISA, IF, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Cancer-Related Cognitive Impairment in Patients With Lung Cancer., PMID:40460355
Immunotherapy against tau fragment diminishes AD pathology, improving synaptic function and cognition., PMID:40426267
Function and application of brain‑derived neurotrophic factor precursors (Review)., PMID:40341415
Expression of BDNF in the Cortex and Hippocampus of Mice With Middle Cerebral Artery Occlusion., PMID:40294991
Mechanism by which hyperglycemia regulates precursor of brain-derived neurotrophic factor expression to exacerbate neurological injury and inflammation in a mouse model of spinal cord ischemia-reperfusion injury., PMID:40195659
Stimulation of microglia leads to a rapid antidepressant effect by triggering astrocytic P2Y1Rs and promoting BDNF-mediated neurogenesis in the hippocampus., PMID:40194747
Amyloid-β-regulated gene circuits for programmable Alzheimer's disease therapy., PMID:40161792
BDNF secreted by mesenchymal stem cells improves aged oocyte quality and development potential by activating the ERK1/2 pathway., PMID:40122822
Ultra-Sensitive Nanoplatform for Detection of Brain-Derived Neurotrophic Factor Using Silica-Coated Gold Nanoparticles with Enzyme-Formed Quantum Dots., PMID:39942807
Novel plasma cytokines identified and validated in children during lead exposure according to the new updated BLRV., PMID:39639084
Immunoglobulin G N-glycan markers of mild cognitive impairment in a Chinese population with cerebrovascular stenosis: A case-control study., PMID:39616857
Anti-NMDAR1 antibody impairs dendritic branching in immature cultured neurons., PMID:39434510
A Nanobody-Based Proximity Ligation Assay Detects Constitutive and Stimulus-Regulated Native Arc/Arg3.1 Oligomers in Hippocampal Neuronal Dendrites., PMID:39367947
[Significance of immunological markers in patients with obstructive sleep apnea and comorbid pathology]., PMID:39269296
Immune Cells Promote BDNF Expression by Infiltrated Macrophages via Interleukin 4 in the Cerebral Ischemia of Male Rats., PMID:39235282
Positive Allosteric Modulators of Trk Receptors for the Treatment of Alzheimer's Disease., PMID:39204102
Kappa Opioid Receptor Activation Induces Epigenetic Silencing of Brain-Derived Neurotropic Factor via HDAC5 in Depression., PMID:39190549
The forensic aspects of suicide and neurotrophin factors: a research study., PMID:39170712
Intranasal LAG3 antibody infusion induces a rapid antidepressant effect via the hippocampal ERK1/2-BDNF signaling pathway in chronically stressed mice., PMID:39153731
Targeting NGF but not VEGFR1 or BDNF signaling reduces endometriosis-associated pain in mice., PMID:39142441
Effects of house-cultivated edible bird's nest on immunoglobulin and cytokine release in vitro., PMID:39077458
BDNF/TrkB signalling, in cooperation with muscarinic signalling, retrogradely regulates PKA pathway to phosphorylate SNAP-25 and Synapsin-1 at the neuromuscular junction., PMID:39044222
The Effect of Intranasal Administration of Gangliosides on the Viability of CA1 Hippocampal Neurons in Rat Two-Vessel Occlusion Model of Forebrain Ischemia/Reperfusion Injury., PMID:38907060
Targeting TrkB-PSD-95 coupling to mitigate neurological disorders., PMID:38886937
The comparative effects of bone marrow mesenchymal stem cells and supernatant transplantation on demyelination and inflammation in cuprizone model., PMID:38787497
Altered serum levels of neuronal proteins and antibodies to them in occupational diseases of the nervous system., PMID:38711410
A Four-Week High-Fat Diet Induces Anxiolytic-like Behaviors through Mature BDNF in the mPFC of Mice., PMID:38672038
PM2.5 exposure upregulates pro-inflammatory protein expression in human microglial cells via oxidant stress and TLR4/NF-κB pathway., PMID:38657455
A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and neuroinflammation., PMID:38599251
Autoimmune and neuropsychiatric phenotypes in a Mecp2 transgenic mouse model on C57BL/6 background., PMID:38524134
Antidepressant-like effects of hyperoside on chronic stress-induced depressive-like behaviors in mice: Gut microbiota and short-chain fatty acids., PMID:38492650
TrkB-BDNF Signalling and Arc/Arg3.1 Immediate Early Genes in the Anterior Cingulate Cortex and Hippocampus: Insights into Novel Memory Milestones Through Behavioural Tagging., PMID:38485841
Biomarkers and Tourette syndrome: a systematic review and meta-analysis., PMID:38385037
Proteomic, miRNA and bacterial biomarker patterns in atopic dermatitis patients and their course upon anti-IL-4Rα therapy., PMID:38379385
Localization of truncated TrkB and co-expression with full-length TrkB in the cerebral cortex of adult mice., PMID:38335799
A pathogenic role for brain-derived neurotrophic factor (BDNF) in fibrous dysplasia of bone., PMID:38331308
The Effects of Polyphenol Supplementation on BDNF, Cytokines and Cognition in Trained Male Cyclists following Acute Ozone Exposure during High-Intensity Cycling., PMID:38257125
Expression of Brain-Derived Neurotrophic Factor in Human Spiral Ganglia Neurons after Cochlear Implantation., PMID:38238917
Panaxcerol D from Panax ginseng ameliorates the memory impairment induced by cholinergic blockade or Aβ25-35 peptide in mice., PMID:38223823
Blue light at night produces stress-evoked heightened aggression by enhancing brain-derived neurotrophic factor in the basolateral amygdala., PMID:38187456
Genetic knockout of NTRK2 by CRISPR/Cas9 decreases neurogenesis and favors glial progenitors during differentiation of neural progenitor stem cells., PMID:38161998
Isolation and Identification of the High-Affinity DNA Aptamer Target to the Brain-Derived Neurotrophic Factor (BDNF)., PMID:38149631
Dexmedetomidine Stereotaxic Injection Alleviates Neuronal Loss Following Bilateral Common Carotid Artery Occlusion via Up-Regulation of BDNF Expression., PMID:38148065
ProBDNF contributed to patrolling monocyte infiltration and renal damage in systemic lupus erythematosus., PMID:38142902
Obligatory role of microglia-mobilized hippocampal CREB-BDNF signaling in the prophylactic effect of β-glucan on chronic stress-induced depression-like behaviors in mice., PMID:38142848
Distinctive mesenchymal-like neurofibroma stem cells shape NF1 clinical phenotypes controlled by BDNF microenvironment., PMID:38042136
β-glucan, a specific immuno-stimulant, produces rapid antidepressant effects by stimulating ERK1/2-dependent synthesis of BDNF in the hippocampus., PMID:37939990
Changes in Reaction Time, Balance and Neuroplasticity after Exercise with a Face Mask in Male Adults with Mild COVID-19 Symptoms., PMID:37893874
Bispecific antibody shuttles targeting CD98hc mediate efficient and long-lived brain delivery of IgGs., PMID:37890480
Synaptic proteins in neuron-derived extracellular vesicles as biomarkers for Alzheimer's disease: novel methodology and clinical proof of concept., PMID:37842184
For research use only. Not for human or drug use.
