Catalog No.
YVV24501
Expression system
E. coli
Species
Lake Victoria marburgvirus (strain Popp-67) (MARV) (Marburg virus (strain West Germany/Popp/1967))
Protein length
Ser204-Ile329
Predicted molecular weight
16.06 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q03039
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Polymerase cofactor VP35, Marburg VP35, mVP35, VP35
From protein to immunology: comprehensive insights into Marburg virus vaccines, mechanism, and application., PMID:40025302
Design of a novel multi-epitope vaccine against Marburg virus using immunoinformatics studies., PMID:38970027
Single-cell image-based genetic screens systematically identify regulators of Ebola virus subcellular infection dynamics., PMID:38617272
Designing a novel and combinatorial multi-antigenic epitope-based vaccine "MarVax" against Marburg virus-a reverse vaccinology and immunoinformatics approach., PMID:38012426
Ebola virus VP35 perturbs type I interferon signaling to facilitate viral replication., PMID:37839549
Ebola and Marburg virus VP35 coiled-coil validated as antiviral target by tripartite split-GFP complementation., PMID:36325051
Marburg Virus VP30 Is Required for Transcription Initiation at the Glycoprotein Gene., PMID:35997284
Filovirus VP24 Proteins Differentially Regulate RIG-I and MDA5-Dependent Type I and III Interferon Promoter Activation., PMID:35069519
Impact of Měnglà Virus Proteins on Human and Bat Innate Immune Pathways., PMID:32295912
Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment., PMID:31337716
Transcriptomics Reveal Antiviral Gene Induction in the Egyptian Rousette Bat Is Antagonized In Vitro by Marburg Virus Infection., PMID:30400182
Marburg Virus Viral Protein 35 Inhibits Protein Kinase R Activation in a Cell Type-Specific Manner., PMID:30165526
Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription., PMID:30135121
Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide Reveals a Conserved Drug Target for Filovirus., PMID:28659479
Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time., PMID:28611428
Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus., PMID:28566377
Innate Immune Responses of Bat and Human Cells to Filoviruses: Commonalities and Distinctions., PMID:28122983
Novel activities by ebolavirus and marburgvirus interferon antagonists revealed using a standardized in vitro reporter system., PMID:27930961
Crystal Structure of the Marburg Virus VP35 Oligomerization Domain., PMID:27847355
Effects of Filovirus Interferon Antagonists on Responses of Human Monocyte-Derived Dendritic Cells to RNA Virus Infection., PMID:26962215
Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins., PMID:26876165
Lloviu virus VP24 and VP35 proteins function as innate immune antagonists in human and bat cells., PMID:26255028
Recombinant Marburg viruses containing mutations in the IID region of VP35 prevent inhibition of Host immune responses., PMID:25531184
Exploring the mechanism how Marburg virus VP35 recognizes and binds dsRNA by molecular dynamics simulations and free energy calculations., PMID:24459115
Development of a reverse genetics system to generate recombinant Marburg virus derived from a bat isolate., PMID:24074586
Mapping of conserved and species-specific antibody epitopes on the Ebola virus nucleoprotein., PMID:23702199
Sequence variability in viral genome non-coding regions likely contribute to observed differences in viral replication amongst MARV strains., PMID:23510675
Structural basis for Marburg virus VP35-mediated immune evasion mechanisms., PMID:23185024
Marburg virus VP35 can both fully coat the backbone and cap the ends of dsRNA for interferon antagonism., PMID:23028316
Rapid detection of filoviruses by real-time TaqMan polymerase chain reaction assays., PMID:23001480
Recombinant Marburg virus expressing EGFP allows rapid screening of virus growth and real-time visualization of virus spread., PMID:21987762
Filoviral immune evasion mechanisms., PMID:21994800
Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles., PMID:20504928
Establishment and application of an infectious virus-like particle system for Marburg virus., PMID:20071483
Evasion of the interferon-mediated antiviral response by filoviruses., PMID:21994610
Evasion of interferon responses by Ebola and Marburg viruses., PMID:19694547
The Ebola virus ribonucleoprotein complex: a novel VP30-L interaction identified., PMID:19041915
Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein., PMID:17958906
VP24 of Marburg virus influences formation of infectious particles., PMID:16227263
Inhibition of Marburg virus protein expression and viral release by RNA interference., PMID:15784912
For research use only. Not for human or drug use.
