Catalog No.
YVV24401
Expression system
E. coli
Species
Lake Victoria marburgvirus (strain Angola/2005) (MARV)
Protein length
Met1-Leu695
Predicted molecular weight
79.95 kDa
Nature
Recombinant
Endotoxin level
Please contact with the lab for this information.
Purity
>90% as determined by SDS-PAGE.
Accession
Q1PD53
Applications
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Form
Lyophilized
Storage buffer
Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Reconstitution
Reconstitute in sterile water for a stock solution.
Shipping
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternative Names
Nucleoprotein, Nucleocapsid protein, NP
Ebola and Marburg viruses IgG detections in small ruminants and dogs from villages within outbreak areas in Gabon., PMID:40043032
From protein to immunology: comprehensive insights into Marburg virus vaccines, mechanism, and application., PMID:40025302
Rapid Development of Modified Vaccinia Virus Ankara (MVA)-Based Vaccine Candidates Against Marburg Virus Suitable for Clinical Use in Humans., PMID:39771978
Cheminformatics-based analysis identified (Z)-2-(2,5-dimethoxy benzylidene)-6-(2-(4-methoxyphenyl)-2-oxoethoxy) benzofuran-3(2H)-one as an inhibitor of Marburg replication by interacting with NP., PMID:39216611
The cellular protein phosphatase 2A is a crucial host factor for Marburg virus transcription., PMID:39194238
Structural insights on the nucleoprotein C-terminal domain of Měnglà virus., PMID:37888996
Ebola Virus Activates IRE1α-Dependent XBP1u Splicing., PMID:36680162
Histopathologic and Immunohistochemical Evaluation of Induced Lesions, Tissue Tropism and Host Responses following Experimental Infection of Egyptian Rousette Bats (Rousettus aegyptiacus) with the Zoonotic Paramyxovirus, Sosuga Virus., PMID:35746749
Structural insights into the interactions between lloviu virus VP30 and nucleoprotein., PMID:35649303
Structural insight into Marburg virus nucleoprotein-RNA complex formation., PMID:35246537
Marburg and Ebola Virus mRNA 3' Untranslated Regions Contain Negative Regulators of Translation That Are Modulated by ADAR1 Editing., PMID:34346762
Development of a multiplex microsphere immunoassay for the detection of antibodies against highly pathogenic viruses in human and animal serum samples., PMID:33095766
Sudan Ebolavirus VP35-NP Crystal Structure Reveals a Potential Target for Pan-Filovirus Treatment., PMID:31337716
Generation and Characterization of Anti-Filovirus Nucleoprotein Monoclonal Antibodies., PMID:30875741
Phosphorylated VP30 of Marburg Virus Is a Repressor of Transcription., PMID:30135121
Pan-Filovirus Serum Neutralizing Antibodies in a Subset of Congolese Ebolavirus Infection Survivors., PMID:30107445
Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies., PMID:29038656
Intracellular Crosslinking of Filoviral Nucleoproteins with Xintrabodies Restricts Viral Packaging., PMID:29021793
Crystal Structure of the Marburg Virus Nucleoprotein Core Domain Chaperoned by a VP35 Peptide Reveals a Conserved Drug Target for Filovirus., PMID:28659479
Deep-sequencing of Marburg virus genome during sequential mouse passaging and cell-culture adaptation reveals extensive changes over time., PMID:28611428
Structural Insight into Nucleoprotein Conformation Change Chaperoned by VP35 Peptide in Marburg Virus., PMID:28566377
One-Step Reverse Transcription-Polymerase Chain Reaction for Ebola and Marburg Viruses., PMID:27413652
Novel Chemical Ligands to Ebola Virus and Marburg Virus Nucleoproteins Identified by Combining Affinity Mass Spectrometry and Metabolomics Approaches., PMID:27403722
Human Survivors of Disease Outbreaks Caused by Ebola or Marburg Virus Exhibit Cross-Reactive and Long-Lived Antibody Responses., PMID:27335383
Virus-Like Particle Vaccination Protects Nonhuman Primates from Lethal Aerosol Exposure with Marburgvirus (VLP Vaccination Protects Macaques against Aerosol Challenges)., PMID:27070636
Molecular architecture of the nucleoprotein C-terminal domain from the Ebola and Marburg viruses., PMID:26894534
Deep sequencing identifies noncanonical editing of Ebola and Marburg virus RNAs in infected cells., PMID:25370495
Interaction with Tsg101 is necessary for the efficient transport and release of nucleocapsids in marburg virus-infected cells., PMID:25330247
Determination of specific antibody responses to the six species of ebola and Marburg viruses by multiplexed protein microarrays., PMID:25230936
Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA., PMID:25143366
Development of a reverse genetics system to generate recombinant Marburg virus derived from a bat isolate., PMID:24074586
Protection against lethal Marburg virus infection mediated by lipid encapsulated small interfering RNA., PMID:23990568
Mapping of conserved and species-specific antibody epitopes on the Ebola virus nucleoprotein., PMID:23702199
Sequence variability in viral genome non-coding regions likely contribute to observed differences in viral replication amongst MARV strains., PMID:23510675
Generation and epitope mapping of a monoclonal antibody against nucleoprotein of Ebola virus., PMID:23457784
Characterization of filovirus protein-protein interactions in mammalian cells using bimolecular complementation., PMID:21987757
Advances in virus-like particle vaccines for filoviruses., PMID:21987741
Detection of all known filovirus species by reverse transcription-polymerase chain reaction using a primer set specific for the viral nucleoprotein gene., PMID:21093485
Tsg101 is recruited by a late domain of the nucleocapsid protein to support budding of Marburg virus-like particles., PMID:20504928
Establishment and application of an infectious virus-like particle system for Marburg virus., PMID:20071483
Discovery of common marburgvirus protective epitopes in a BALB/c mouse model., PMID:19712478
Production and characterization of monoclonal antibodies to nucleoprotein of Marburg virus., PMID:19108615
The Ebola virus ribonucleoprotein complex: a novel VP30-L interaction identified., PMID:19041915
Ebola virus-like particle-based vaccine protects nonhuman primates against lethal Ebola virus challenge., PMID:17940980
Nucleocapsid formation and RNA synthesis of Marburg virus is dependent on two coiled coil motifs in the nucleoprotein., PMID:17958906
Interaction of Tsg101 with Marburg virus VP40 depends on the PPPY motif, but not the PT/SAP motif as in the case of Ebola virus, and Tsg101 plays a critical role in the budding of Marburg virus-like particles induced by VP40, NP, and GP., PMID:17301151
VP24 of Marburg virus influences formation of infectious particles., PMID:16227263
Inhibition of Marburg virus protein expression and viral release by RNA interference., PMID:15784912
For research use only. Not for human or drug use.
