Catalog No.
VXX02301
Species reactivity
Candida albicans
Host species
Human
Isotype
IgG1
Clonality
Monoclonal
Target
Heat shock protein 90 homolog, HSP90, CAALFM_C702030WA, CaJ7.0234, CaO19.13868, CaO19.6515
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P46598
Applications
Blocking, ELISA
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
Iv0155
Extracellular Hsp90 of Candida albicans contributes to the virulence of the pathogen by activating the NF-κB signaling pathway and inducing macrophage pyroptosis., PMID:39522202
Potential of Polyethyleneimine as an Adjuvant To Prepare Long-Term and Potent Antifungal Nanovaccine., PMID:35651617
The Role of B-Cells and Antibodies against Candida Vaccine Antigens in Invasive Candidiasis., PMID:34696267
Chitosan hydrogel loaded with recombinant protein containing epitope C from HSP90 of Candida albicans induces protective immune responses against systemic candidiasis., PMID:33482211
Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans., PMID:28783748
Structural characterization of low molecular weight polysaccharide from Astragalus membranaceus and its immunologic enhancement in recombinant protein vaccine against systemic candidiasis., PMID:27106150
Molecular adjuvants based on nonpyrogenic lipophilic derivatives of norAbuMDP/GMDP formulated in nanoliposomes: stimulation of innate and adaptive immunity., PMID:25630814
Serum antibody signature directed against Candida albicans Hsp90 and enolase detects invasive candidiasis in non-neutropenic patients., PMID:25377742
Candida antigens and immune responses: implications for a vaccine., PMID:24957934
Adjuvant effect of polysaccharide from fruits of Physalis alkekengi L. in DNA vaccine against systemic candidiasis., PMID:24815404
Nonspecific effect of Mycograb on amphotericin B MIC., PMID:22508314
Dose range evaluation of Mycograb C28Y variant, a human recombinant antibody fragment to heat shock protein 90, in combination with amphotericin B-desoxycholate for treatment of murine systemic candidiasis., PMID:21502626
Metallochelating liposomes with associated lipophilised norAbuMDP as biocompatible platform for construction of vaccines with recombinant His-tagged antigens: preparation, structural study and immune response towards rHsp90., PMID:21256901
The use of hybrid phage displaying antigen epitope and recombinant protein in the diagnosis of systemic Candida albicans infection in rabbits and cancer patients., PMID:20884151
Systemic and mucosal immunization with Candida albicans hsp90 elicits hsp90-specific humoral response in vaginal mucosa which is further enhanced during experimental vaginal candidiasis., PMID:18608941
Efungumab and caspofungin: pre-clinical data supporting synergy., PMID:18299636
Protective immune responses against systemic candidiasis mediated by phage-displayed specific epitope of Candida albicans heat shock protein 90 in C57BL/6J mice., PMID:16842891
A randomized, blinded, multicenter trial of lipid-associated amphotericin B alone versus in combination with an antibody-based inhibitor of heat shock protein 90 in patients with invasive candidiasis., PMID:16619152
Fungal heat-shock proteins in human disease., PMID:16438680
Fungal antigens expressed during invasive aspergillosis., PMID:16040983
Prophylactic vaccination with phage-displayed epitope of C. albicans elicits protective immune responses against systemic candidiasis in C57BL/6 mice., PMID:15963364
Comparison of protective effect of protein and DNA vaccines hsp90 in murine model of systemic candidiasis., PMID:15954537
The role of antibodies against hsp90 in the treatment of fungal infections., PMID:12942149
Preclinical assessment of the efficacy of mycograb, a human recombinant antibody against fungal HSP90., PMID:12821470
Isolation and partial characterization of Hsp90 from Candida albicans., PMID:12661902
Genistein effects on growth and cell cycle of Candida albicans., PMID:11287745
Isolation and identification of a 92-kDa stress induced protein from Candida albicans., PMID:10872511
Estrogen effects on Candida albicans: a potential virulence-regulating mechanism., PMID:10762574
Preliminary assessment of a human recombinant antibody fragment to hsp90 in murine invasive candidiasis., PMID:7539475
The role of hsp90 in fungal infection., PMID:1466751
For research use only. Not for human or drug use.
