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Anti-CDH3 Polyclonal Antibody

Catalog #:   PHD50501 Specific References (25) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P22223
Overview

Catalog No.

PHD50501

Species reactivity

Human, Mouse, Rat

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CDH3 (Gly371-Leu660).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Placental cadherin,CDH3,Cadherin-3,P-cadherin,CDHP

Purification

Purified by antigen affinity column.

Accession

P22223

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • Western blot
    Various lysates were subjected to SDS PAGE followed by western blot with CDH3 antibody (PHD50501) at 0.55ug/ml.

    Lane 1: BXPC3 cell lysate

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 91 kDa
    Observed MW: 91,120 kDa
  • Western Blot
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CDH3 antibody (PHD50501) at 1 µg/ml.

    Lane 1: Recombinant Protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 34 kDa
    Observed MW: 34 kDa
References

A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer., PMID:39654063

Serum Level of Cadherin-P (CDH3) Is a Novel Predictor of Cardiovascular Events Related to Atherosclerosis in a 3-Year Follow-Up Study., PMID:39518432

Comprehensive multiplexed autoantibody profiling of patients with advanced urothelial cancer., PMID:38309723

Dosimetry of a Novel 111Indium-Labeled Anti-P-Cadherin Monoclonal Antibody (FF-21101) in Non-Human Primates., PMID:37760501

The Role of Radiolabeled Monoclonal Antibodies in Cancer Imaging and ADC Treatment., PMID:36383907

Discovery of targeted expression data for novel antibody-based and chimeric antigen receptor-based therapeutics in soft tissue sarcomas using RNA-sequencing: clinical implications., PMID:34656365

The expression and prognostic relevance of CDH3 in tongue squamous cell carcinoma., PMID:34580913

PCA062, a P-cadherin Targeting Antibody-Drug Conjugate, Displays Potent Antitumor Activity Against P-cadherin-expressing Malignancies., PMID:33879555

Preclinical Characterization of the Radioimmunoconjugate 111In or 90Y-FF-21101 Against a P-Cadherin-Expressing Tumor in a Mouse Xenograft Model and a Nonhuman Primate., PMID:32737245

Increased cardiovascular and atherosclerosis markers in blood of older patients with atopic dermatitis., PMID:31622668

Molecular pathology of the luminal class of urothelial tumors., PMID:31232464

Novel method for rapid identification of micropapillary or solid components in early-stage lung adenocarcinoma., PMID:30180981

Cell surface markers for the identification and study of human naive pluripotent stem cells., PMID:29227830

Discovery of novel plasma proteins as biomarkers for the development of incisional hernias after midline incision in patients with colorectal cancer: The ColoCare study., PMID:27745870

Stem Cell Surface Marker Expression Defines Late Stages of Reprogramming to Pluripotency in Human Fibroblasts., PMID:27160704

Limbal dermoid epithelium shares phenotypic characteristics common to both hair epidermal and limbal epithelial stem cells., PMID:23573994

In vivo therapeutic effect of CDH3/P-cadherin-targeting radioimmunotherapy., PMID:22223257

A mechanoresponsive cadherin-keratin complex directs polarized protrusive behavior and collective cell migration., PMID:22169071

PF-03732010: a fully human monoclonal antibody against P-cadherin with antitumor and antimetastatic activity., PMID:20829331

The conserved miR-51 microRNA family is redundantly required for embryonic development and pharynx attachment in Caenorhabditis elegans., PMID:20421599

Molecular characterization of cultured adult human liver progenitor cells., PMID:19874131

Identification of human embryonic stem cell surface markers by combined membrane-polysome translation state array analysis and immunotranscriptional profiling., PMID:19650036

Inhibition of cell adhesion by xARVCF indicates a regulatory function at the plasma membrane., PMID:18729204

Overexpressed P-cadherin/CDH3 promotes motility of pancreatic cancer cells by interacting with p120ctn and activating rho-family GTPases., PMID:15833838

cDNA microarray analysis of genes associated with ERBB2 (HER2/neu) overexpression in human mammary luminal epithelial cells., PMID:12730682

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CDH3 Polyclonal Antibody [PHD50501]
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