Catalog No.
PHD47801
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human VDAC1 (Met1-Ala283).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:2000-1:8000
Target
Outer mitochondrial membrane protein porin 1,Plasmalemmal porin,hVDAC1,Porin 31HL,Porin 31HM,Voltage-dependent anion-selective channel protein 1,VDAC1,VDAC-1,VDAC
Purification
Purified by antigen affinity column.
Accession
P21796
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Deciphering melanophagy: role of the PTK2-ITCH-MLANA-OPTN cascade on melanophagy in melanocytes., PMID:39477686
Sulindac prevents increased mitochondrial VDAC1 expression and cell surface mistargeting induced by pathological conditions in retinal cells., PMID:39181068
Quadriceps muscle atrophy after non-invasive anterior cruciate ligament injury: evidence linking to autophagy and mitophagy., PMID:38496299
Neuronal Protection by Ha-RAS-GTPase Signaling through Selective Downregulation of Plasmalemmal Voltage-Dependent Anion Channel-1., PMID:38474278
Lack of mitochondrial complex I assembly factor NDUFAF2 results in a distinctive infantile-onset brainstem neurodegenerative disease with early lethality., PMID:38419071
Inactivation of the TIM complex components leads to a decrease in the level of DNA import into Arabidopsis mitochondria., PMID:38239966
Senecavirus A induces mitophagy to promote self-replication through direct interaction of 2C protein with K27-linked ubiquitinated TUFM catalyzed by RNF185., PMID:38084826
Identification and validation of a novel necroptosis-related molecular signature to evaluate prognosis and immune features in breast cancer., PMID:37787960
Trastuzumab-induced cardiomyopathy via ferroptosis-mediated mitochondrial dysfunction., PMID:37392951
Voltage-Dependent Anion Channel 1 Expression in Oral Malignant and Premalignant Lesions., PMID:37046443
Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane., PMID:36979492
Resveratrol Protects against Zearalenone-Induced Mitochondrial Defects during Porcine Oocyte Maturation via PINK1/Parkin-Mediated Mitophagy., PMID:36136579
Analysis of hemisphere-dependent effects of unilateral intrastriatal injection of α-synuclein pre-formed fibrils on mitochondrial protein levels, dynamics, and function., PMID:35606853
Cannabinoid Receptor 1 associates to different molecular complexes during GABAergic neuron maturation., PMID:33942314
A plausible involvement of plasmalemmal voltage-dependent anion channel 1 in the neurotoxicity of 15-deoxy-Δ12,14 -prostaglandin J2., PMID:33200588
Raft-like lipid microdomains drive autophagy initiation via AMBRA1-ERLIN1 molecular association within MAMs., PMID:33034545
Decoding mitochondrial heterogeneity in single muscle fibres by imaging mass cytometry., PMID:32948797
The Mitochondrial Protein VDAC1 at the Crossroads of Cancer Cell Metabolism: The Epigenetic Link., PMID:32331482
Identification of a new aggressive axis driven by ciliogenesis and absence of VDAC1-ΔC in clear cell Renal Cell Carcinoma patients., PMID:32194829
17β-estradiol inhibits H2O2-induced senescence in HUVEC cells through upregulating SIRT3 expression and promoting autophagy., PMID:32172411
Fungal allergen-induced IL-33 secretion involves cholesterol-dependent, VDAC-1-mediated ATP release from the airway epithelium., PMID:32103508
VDAC1 is essential for neurite maintenance and the inhibition of its oligomerization protects spinal cord from demyelination and facilitates locomotor function recovery after spinal cord injury., PMID:31575916
Visualization of Ceramide-Associated Proteins in Ceramide-Rich Platforms Using a Cross-Linkable Ceramide Analog and Proximity Ligation Assays With Anti-ceramide Antibody., PMID:31475148
Novel Carbazole-Piperazine Hybrid Small Molecule Induces Apoptosis by Targeting BCL-2 and Inhibits Tumor Progression in Lung Adenocarcinoma in Vitro and Xenograft Mice Model., PMID:31450709
PINK1/parkin-mediated mitophagy pathway is related to neuroprotection by carnosic acid in SH-SY5Y cells., PMID:30707903
Preserving Insulin Secretion in Diabetes by Inhibiting VDAC1 Overexpression and Surface Translocation in β Cells., PMID:30293774
OMIP-048 MC: Quantification of calcium sensors and channels expression in lymphocyte subsets by mass cytometry., PMID:30080305
TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics., PMID:29715546
Reduction of endoplasmic reticulum- mitochondria interactions in beta cells from patients with type 2 diabetes., PMID:28742858
Study of Endoplasmic Reticulum and Mitochondria Interactions by In Situ Proximity Ligation Assay in Fixed Cells., PMID:28060261
Sirt3-mediated mitophagy protects tumor cells against apoptosis under hypoxia., PMID:27270321
Novel Biomarker Proteins in Chronic Lymphocytic Leukemia: Impact on Diagnosis, Prognosis and Treatment., PMID:27078856
Cigarette smoke effects on TSPO and VDAC expression in a cellular lung cancer model., PMID:26378498
Plasminogen kringle 5 induces endothelial cell apoptosis by triggering a voltage-dependent anion channel 1 (VDAC1) positive feedback loop., PMID:25296756
Altered dopamine homeostasis differentially affects mitochondrial voltage-dependent anion channels turnover., PMID:24998333
External mitochondrial NADH-dependent reductase of redox cyclers: VDAC1 or Cyb5R3?, PMID:24945955
Live cell interactome of the human voltage dependent anion channel 3 (VDAC3) revealed in HeLa cells by affinity purification tag technique., PMID:24865465
Tespa1 is a novel component of mitochondria-associated endoplasmic reticulum membranes and affects mitochondrial calcium flux., PMID:23501103
On a fully closed state of native human type-1 VDAC enriched in Nonidet P40., PMID:23000107
Prostacyclin receptor-mediated ATP release from erythrocytes requires the voltage-dependent anion channel., PMID:22159995
Identification of Bax-voltage-dependent anion channel 1 complexes in digitonin-solubilized cerebellar granule neurons., PMID:21951169
The use of anti-VDAC2 antibody for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced acrosome reaction., PMID:21347391
Proteomics-based identification of a group of apoptosis-related proteins and biomarkers in gastric cancer., PMID:21165559
Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS., PMID:20797535
Beneficial effect of human anti-amyloid-beta active immunization on neurite morphology and tau pathology., PMID:20360050
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1., PMID:20098416
Voltage-dependent anion channels 1 and 2 are expressed in porcine oocytes., PMID:19630752
Crystal packing analysis of murine VDAC1 crystals in a lipidic environment reveals novel insights on oligomerization and orientation., PMID:19574737
Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathway., PMID:19487148
The proteome of the presynaptic active zone: from docked synaptic vesicles to adhesion molecules and maxi-channels., PMID:19187093
For research use only. Not for human or drug use.
