Catalog No.
FHF88330
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
T1, DER4, Interleukin-1 receptor-like 1, ST2, IL1RL1, Protein ST2
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
Q01638
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
SAA1400
Enhancing the Affinity of a Novel Selective scFv for Soluble ST2 through Computational Design., PMID:40417773
Fluorescence Aptasensor for sST2 Detection Using In Vitro Selected Aptamers., PMID:40370093
Drug survival of omalizumab in atopic asthma: Impact of clinical and genetic variables., PMID:40189906
A novel optical fiber immunosensor for detection of heart failure marker ST2 based on MoS2-modified D-shaped ExTFG., PMID:40120516
Soluble ST2 is an early marker and treatment target for hypertensive nephrosclerosis signatured in glomerular mesangial cells., PMID:40096886
IL-33 protects from recurrent C. difficile infection by restoration of humoral immunity., PMID:40048372
IL-33 signaling is dispensable for the IL-10-induced enhancement of mast cell responses during food allergy., PMID:39935481
IL-33/ST2 axis in diverse diseases: regulatory mechanisms and therapeutic potential., PMID:39925809
IL-33/ST2 axis mediates diesel exhaust particles-induced mast cell activation., PMID:39707175
Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells., PMID:39632879
Dural Tregs driven by astrocytic IL-33 mitigate depression through the EGFR signals in mPFC neurons., PMID:39592709
Interleukin-33 Deficiency Protects the Skin From Ulcer Formation in an Ischemia-Reperfusion-Induced Decubitus Mouse Model., PMID:39555678
IL-33/ST2 enhances MMP-12 expression by macrophages to mediate inflammatory and immune response in IgG4-Related Ophthalmic Disease., PMID:39299101
A model-based approach using GSK3772847, an anti-interleukin-33 receptor monoclonal antibody, as a showcase to predict SC administration PK and free target dynamics based on PK and total target measurements after IV administration., PMID:39258338
Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease., PMID:39183511
Edwardsiella tarda induces airways inflammation and production of autoantibodies against lung tissues through regulation of the IL-33-ST2 axis., PMID:39126327
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma., PMID:39125709
ILC2s induce Treg but not Th2-type immunity through IL-33/ST2 pathway in pulmonary tuberculosis., PMID:38990986
The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin., PMID:38858740
Maintenance of caecal homeostasis by diverse adaptive immune cells in the rhesus macaque., PMID:38707998
Hydrangea serrata extract attenuates PM-exacerbated airway inflammation in the CARAS model by modulating the IL-33/ST2/NF-κB signaling pathway., PMID:38631146
Multiplex Proteomics in the Identification of Potential Biomarkers of Very Severe Sinusoidal Obstruction Syndrome/Veno-Occlusive Disease in Allogeneic Hematopoietic Cell Transplant Patients Treated with Defibrotide., PMID:38330921
ST2-Mediated Neutrophilic Airway Inflammation: A Therapeutic Target for Patients With Uncontrolled Asthma., PMID:38262389
Interleukin-33/ST2 axis involvement in atrial remodeling and arrhythmogenesis., PMID:38244770
Strategies targeting IL-33/ST2 axis in the treatment of allergic diseases., PMID:37981174
Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex., PMID:37442582
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype., PMID:37108192
Interleukin-33 Mediates Cardiomyopathy After Acute Kidney Injury by Signaling to Cardiomyocytes., PMID:36695175
A comparative study of IL-33 and its receptor ST2 in a C57BL/6 J mouse model of pulmonary Cryptococcus neoformans infection., PMID:36367554
Phase 2 randomized clinical trial of astegolimab in patients with moderate to severe atopic dermatitis., PMID:36041655
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues., PMID:36012165
IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation., PMID:35940987
Interleukin-33 (IL-33): A critical review of its biology and the mechanisms involved in its release as a potent extracellular cytokine., PMID:35640416
A rapid and quantitative detection method for plasma soluble growth stimulating gene protein 2 based on time resolved fluorescence immunochromatography., PMID:35608240
Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma., PMID:35578178
IL-25 blockade augments antiviral immunity during respiratory virus infection., PMID:35508632
The Merkel Cell Polyomavirus T-Antigens and IL-33/ST2-IL1RAcP Axis: Possible Role in Merkel Cell Carcinoma., PMID:35409061
Mast Cells Differentiated in Synovial Fluid and Resident in Osteophytes Exalt the Inflammatory Pathology of Osteoarthritis., PMID:35008966
Blockade or deficiency of PD-L1 expression in intestinal allograft accelerates graft tissue injury in mice., PMID:34679256
Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling., PMID:34650552
Inhibition of NF-κB/IL-33/ST2 Axis Ameliorates Acute Bronchiolitis Induced by Respiratory Syncytial Virus., PMID:34395633
Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis., PMID:34373564
Safety and efficacy of itepekimab in patients with moderate-to-severe COPD: a genetic association study and randomised, double-blind, phase 2a trial., PMID:34302758
Astegolimab (anti-ST2) efficacy and safety in adults with severe asthma: A randomized clinical trial., PMID:33872652
The IL33 receptor ST2 contributes to mechanical hypersensitivity in mice with neuropathic pain., PMID:33596932
Role of the IL-33/ST2 axis in cigarette smoke-induced airways remodelling in chronic obstructive pulmonary disease., PMID:33589512
Endothelial cells response to neutrophil-derived extracellular vesicles miRNAs in anti-PR3 positive vasculitis., PMID:33527387
Persistence of mature dendritic cells, TH2A, and Tc2 cells characterize clinically resolved atopic dermatitis under IL-4Rα blockade., PMID:33483337
Nuclear IL-33 restrains the early conversion of fibroblasts to an extracellular matrix-secreting phenotype., PMID:33420328
Development of a Novel Homogeneous Nanoparticle-Based Assay for Rapid and High-Throughput Quantitation of the sST2 Protein in Human Serum., PMID:33408473
For research use only. Not for human or drug use.
