Catalog No.
FHE67920
Species reactivity
Human
Host species
Mouse
Isotype
IgG2a, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
CXCR3, G protein-coupled receptor 9, CXC-R3, Interferon-inducible protein 10 receptor, IP-10 receptor, C-X-C chemokine receptor type 3, GPR9, CD183, CKR-L2, CXCR-3
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P49682
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
5H7
FGFR4 promotes CAF activation through the CXCL10-CXCR3 axis in colon cancer., PMID:40447617
Development of DPP-4-resistant CXCL9-Fc and CXCL10-Fc chemokines for effective cancer immunotherapy., PMID:40238455
Cxcr3 promotes protection from colorectal cancer liver metastasis by driving NK cell infiltration and plasticity., PMID:40168086
Reconstitution of CXCR3+ CCR6+ Th17.1-Like T Cells in Response to Ofatumumab Therapy in Patients With Multiple Sclerosis., PMID:40164501
T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis., PMID:40107244
Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development., PMID:39932316
NKG2C and NKG2A coexpression defines a highly functional antiviral NK population in spontaneous HIV control., PMID:39288262
Phenotypic profiling of human induced regulatory T cells at early differentiation: insights into distinct immunosuppressive potential., PMID:39264416
Regulatory T and CXCR3+ Circulating Tfh Cells Concordantly Shape the Neutralizing Antibody Responses in Individuals Who Have Recovered from Mild COVID-19., PMID:39052730
Varied immune responses of HBV-specific B cells in patients undergoing pegylated interferon-alpha treatment for chronic hepatitis B., PMID:38992769
[Clinicopathological characteristics of the CD8+ T lymphocytes infiltration and its mechanism in distinct molecular subtype of medulloblastoma]., PMID:38864138
Diagnostic accuracy and cellular origin of pleural fluid CXCR3 ligands for tuberculous pleural effusion., PMID:38663252
Expressions of CXCR3 and PD-1 on T cells and their clinical relevance in colorectal cancer., PMID:38583239
Twin study dissects CXCR3+ memory B cells as non-heritable feature in multiple sclerosis., PMID:38531361
Cx3Mab-4: A Novel Anti-Mouse CXCR3 Monoclonal Antibody for Flow Cytometry., PMID:38507670
Autoantibodies against the chemokine receptor 3 predict cardiovascular risk., PMID:37941454
Autoreactive B cells in rheumatoid arthritis include mainly activated CXCR3+ memory B cells and plasmablasts., PMID:37725442
Combination treatment of a novel CXCR3 antagonist ACT-777991 with an anti-CD3 antibody synergistically increases persistent remission in experimental models of type 1 diabetes., PMID:37458220
Glucocorticoids target the CXCL9/CXCL10-CXCR3 axis and confer protection against immune-mediated kidney injury., PMID:36355429
Transcriptome and TCR Repertoire Measurements of CXCR3+ T Follicular Helper Cells Within HIV-Infected Human Lymph Nodes., PMID:35619703
Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity., PMID:35264564
CD8 Treg-Mediated Suppression of Naive CD4+ T Cell Differentiation into Follicular Helper T Cells., PMID:34959235
Altered circulating CCR6+and CXCR3+ T cell subsets are associated with poor renal prognosis in MPO-ANCA-associated vasculitis., PMID:34289887
Circulating CD4+ FoxP3- CXCR5- CXCR3+ PD-1hi cells are elevated in active rheumatoid arthritis and reflect the severity of the disease., PMID:34227243
Tumor infiltrating NK cell (TINK) subsets and functional molecules in patients with breast cancer., PMID:34171565
Immunological Properties of Atopic Dermatitis-Associated Alopecia Areata., PMID:33807704
Intratumoral Plasmid IL12 Expands CD8+ T Cells and Induces a CXCR3 Gene Signature in Triple-negative Breast Tumors that Sensitizes Patients to Anti-PD-1 Therapy., PMID:33593880
Integrated immune dynamics define correlates of COVID-19 severity and antibody responses., PMID:33564749
Autoantibodies against C5aR1, C3aR1, CXCR3, and CXCR4 are decreased in primary Sjogren's syndrome., PMID:33446393
Interferon-γ amplifies airway smooth muscle-mediated CD4+ T cell recruitment by promoting the secretion of C-X-C-motif chemokine receptor 3 ligands., PMID:33337555
Spike-specific circulating T follicular helper cell and cross-neutralizing antibody responses in COVID-19-convalescent individuals., PMID:33199863
The association of Epstein-Barr virus infection with CXCR3+ B-cell development in multiple sclerosis: impact of immunotherapies., PMID:33152118
Potential therapeutic manipulations of the CXCR3 chemokine axis for the treatment of inflammatory fibrosing diseases., PMID:33145014
CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune response., PMID:33127761
High CXCR3 on Leukemic Cells Distinguishes IgHV mut from IgHV unmut in Chronic Lymphocytic Leukemia: Evidence from CD5high and CD5low Clones., PMID:32802894
CD8 Treg Cells Inhibit B-Cell Proliferation and Immunoglobulin Production., PMID:32799212
Molecular Pathways of Colon Inflammation Induced by Cancer Immunotherapy., PMID:32603654
CD52-negative T cells predict acute graft-versus-host disease after an alemtuzumab-based conditioning regimen., PMID:32410220
CXCL10 and CCL21 Promote Migration of Pancreatic Cancer Cells Toward Sensory Neurons and Neural Remodeling in Tumors in Mice, Associated With Pain in Patients., PMID:32330476
In vitro Effects of CD8+ Regulatory T Cells on Human B Cell Subpopulations., PMID:32248193
Macrophage-Derived CXCL9 and CXCL10 Are Required for Antitumor Immune Responses Following Immune Checkpoint Blockade., PMID:31636098
Role of CXCR3 signaling in response to anti-PD-1 therapy., PMID:31521609
Circulating CXCR3+ Tfh cells positively correlate with neutralizing antibody responses in HCV-infected patients., PMID:31300682
Infliximab reduces activated myeloid dendritic cells, different macrophage subsets and CXCR3-positive cells in granuloma annulare., PMID:31290564
Phenotypic Analysis of CD4+ Treg, CD8+ Treg, and Breg Cells in Adult Common Variable Immunodeficiency Patients., PMID:31284281
PD-1+CXCR5-CD4+T cells are correlated with the severity of systemic lupus erythematosus., PMID:31180450
CD21-/low B cells associate with joint damage in rheumatoid arthritis patients., PMID:31141193
Recruitment of CXCR3+ T cells into injured tissues in adult IgA vasculitis patients correlates with disease activity., PMID:30745186
Generation and Characterization of a Functional Nanobody Against Inflammatory Chemokine CXCL10, as a Novel Strategy for the Treatment of Multiple Sclerosis., PMID:30426906
Increase of follicular helper T cells skewed toward a Th1 profile in CVID patients with non-infectious clinical complications., PMID:30219667
For research use only. Not for human or drug use.
