Catalog No.
FHC33350
Species reactivity
Human
Host species
Mouse
Isotype
IgG1, kappa
Clonality
Monoclonal
Conjugation
Unconjugated
Target
CD41, ITGAB, GPIIb, ITGA2B, Platelet membrane glycoprotein IIb, GP2B, Integrin alpha-IIb, GPalpha IIb, GPIIIa, Integrin beta-3, CD61, ITGB3, Platelet membrane glycoprotein IIIa, GP3A
Concentration
1 mg/ml
Endotoxin level
Please contact with the lab for this information.
Purity
>95% as determined by SDS-PAGE.
Purification
Protein A/G purified from cell culture supernatant.
Accession
P08514 & P05106
Applications
FCM
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 0.09% Sodium azide.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Clone ID
OPG2
Evaluation of artificial intelligence-assisted morphological analysis for platelet count estimation., PMID:39032139
Selective isolation of extracellular vesicles from minimally processed human plasma as a translational strategy for liquid biopsies., PMID:35933395
Physiologically-based pharmacokinetic modeling of immunoglobulin and antibody coadministration in patients with primary human immunodeficiency., PMID:35860862
Resolution of platelet count interference due to cytoplasmic fragments of leukaemic cells by flow cytometry in acute myeloid leukaemia., PMID:35504732
Evaluation of Platelet Activation by HIV Protease Inhibitors - The HIV-PLA II Study., PMID:34393518
Glanzmann Thrombasthenia: Perspectives from Clinical Practice on Accurate Diagnosis and Optimal Treatment Strategies., PMID:34149292
Platelet-derived extracellular vesicles are increased in sera of Alzheimer's disease patients, as revealed by Tim4-based assays., PMID:33345458
Performance evaluation of platelet counting of Abbott Alinity hq and Sysmex XN-9000 automated hematology analyzer compared with international reference method., PMID:33217153
Expression of ADP receptor P2Y12, thromboxane A2 receptor and C-type lectin-like receptor 2 in cord blood-derived megakaryopoiesis., PMID:32619120
Platelet surface marker analysis by mass cytometry., PMID:31544564
[Clinical Significance of Platelet Membrane Glycoprotein GPIIb/IIIa in Diagnosis and Treatment of Immune Thrombocytopenia]., PMID:31418387
Megakaryocytic dysfunction in immune thrombocytopenia is linked to autophagy., PMID:30923461
Novel Murine Model of Immune Thrombocytopaenia through Immunized CD41 Knockout Mice., PMID:30630213
Mass Cytometry Reveals Distinct Platelet Subtypes in Healthy Subjects and Novel Alterations in Surface Glycoproteins in Glanzmann Thrombasthenia., PMID:29985398
Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow., PMID:26725377
Accuracy of a New Platelet Count System (PLT-F) Depends on the Staining Property of Its Reagents., PMID:26496387
Avoiding false positive antigen detection by flow cytometry on blood cell derived microparticles: the importance of an appropriate negative control., PMID:25978814
Endothelial and platelet microparticles in patients with antiphospholipid antibodies., PMID:25496997
Flow cytometric immunophenotyping of feline bone marrow cells and haematopoietic progenitor cells using anti-human antibodies., PMID:24065708
Megakaryocytic differentiation of CD133+ hematopoietic stem cells by down-regulation of microRNA-10a., PMID:23321646
Semaphorin 7A inhibits platelet production from CD34+ progenitor cells., PMID:22448926
Multicolor flow cytometry for evaluation of platelet surface antigens and activation markers., PMID:22424855
Flow cytometry analysis of porcine platelets: optimized methods for best results., PMID:22035358
Effects of CXCR1 and CXCR2 inhibition on expansion and differentiation of umbilical cord blood CD133(+) cells into megakaryocyte progenitor cells., PMID:21555225
Pulsed electromagnetic fields decrease proinflammatory cytokine secretion (IL-1β and TNF-α) on human fibroblast-like cell culture., PMID:20372910
Acute megakaryoblastic leukemia in a German Shepherd dog., PMID:19793230
Immunohistochemical detection of intravascular platelet microthrombi in patients with lupus nephritis and anti-phospholipid antibodies., PMID:19542214
Application of bead array technology to simultaneous detection of human leucocyte antigen and human platelet antigen antibodies., PMID:19207165
Hematologic abnormalities and flow cytometric immunophenotyping results in dogs with hematopoietic neoplasia: 210 cases (2002-2006)., PMID:19171020
Validation of platelet counting accuracy with the celltac f automated hematology analyzer., PMID:18924739
Quantitative comparisons of antibody-binding sites of platelet glycoprotein IIb/IIIa in aplastic anemia and idiopathic thrombocytopenic purpura., PMID:18316775
Molecular characterization and expression analysis of the gene coding for the porcine beta(3) integrin subunit (CD61)., PMID:18006249
Reactivity of monoclonal antibodies to human CD antigens with cells from mink., PMID:17681385
Reactivity of cross-reacting monoclonal antibodies with canine leukocytes, platelets and erythrocytes., PMID:17643496
Glanzmann thrombasthenia in an Oldenbourg filly., PMID:17523098
Implementation of monoclonal antibody fluorescence on the Abbott CELL-DYN Sapphire haematology analyser: evaluation of lymphoid, myeloid and platelet markers., PMID:16630212
JAS-R, a new megakaryo-erythroid leukemic cell line that secretes erythropoietin., PMID:16619478
Immunohistological analysis of normal and osteoarthritic human synovial tissue., PMID:16536221
Antiplatelet antibodies and their correlation with clinical findings in childhood immune thrombocytopenic purpura., PMID:15802889
[Clinical and molecular-biological study of a May-Hegglin anomaly family]., PMID:15569536
Platelet depletion by anti-CD41 (alphaIIb) mAb injection early but not late in the course of disease protects against Plasmodium berghei pathogenesis by altering the levels of pathogenic cytokines., PMID:15494426
[Significance of detecting platelet associated antibody and platelet membrane glycoprotein for diagnosis of immune thrombocytopenia]., PMID:15157339
Reversibility versus persistence of GPIIb/IIIa blocker-induced conformational change of GPIIb/IIIa (alphaIIbbeta3, CD41/CD61)., PMID:14617694
Aspirin inhibits surface glycoprotein IIb/IIIa, P-selectin, CD63, and CD107a receptor expression on human platelets., PMID:12695747
Effect of a single dose aspirin on platelets in humans with multiple risk factors for coronary artery disease., PMID:12591106
Platelet counting by the coulter LH 750, sysmex XE 2100, and advia 120: a comparative analysis using the RBC/platelet ratio reference method., PMID:12162684
For research use only. Not for human or drug use.
