Research Grade Anti-Human TWEAK/TNFSF12 (BIIB023)

Catalog No.

DHA69201

Expression system

Mammalian Cells

Species reactivity

Human

Host species

Human

Isotype

IgG1-kappa

Clonality

Monoclonal

Target

TWEAK, DR3LG, TNFSF12, Tumor necrosis factor ligand superfamily member 12, APO3L, TNF-related weak inducer of apoptosis, APO3 ligand

Concentration

1 mg/ml

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

O43508

Applications

Research Grade Biosimilar

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Alternative Names

BIIB023, DHK29401

Clone ID

BIIB023

TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro., PMID:38443977

Population pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody., PMID:26896828

Safety, tolerability, pharmacokinetics, and pharmacodynamics of anti-TWEAK monoclonal antibody in patients with rheumatoid arthritis., PMID:23928094

Role of TWEAK in lupus nephritis: a bench-to-bedside review., PMID:22727560

Document Download

Research Grade Anti-Human TWEAK/TNFSF12 (BIIB023).pdf