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Anti-CD11c/ITGAX Polyclonal Antibody

Catalog #:   PHD41101 Specific References (50) DATASHEET
Host species: Rabbit
Isotype: IgG
Applications: ELISA, IHC, WB
Accession: P20702
Overview

Catalog No.

PHD41101

Species reactivity

Human

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD11c/ITGAX (Phe20-Pro1107).

Tested applications

ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000

Target

Integrin alpha-X,CD11c,Leukocyte adhesion receptor p150,95,Leu M5,Leukocyte adhesion glycoprotein p150,95 alpha chain,CD11 antigen-like family member C,CD11C,ITGAX

Purification

Purified by antigen affinity column.

Accession

P20702

Applications

ELISA, IHC, WB

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Data Image
  • WESTERN BLOT
    Recombinant Protein lysates were subjected to SDS PAGE followed by western blot with CD11c/ITGAX antibody (PHD41101) at 1 μg/ml.

    Lane 1: Recombinant protein

    Second Ab: Goat Anti-Rabbit IgG H&L Polyclonal antibody, HRP (PTB96431) at 0.1 μg/mL.

    Predict MW: 122 kDa
    Observed MW: 122 kDa
References

Inflammatory arthritis immune related adverse events represent a unique autoimmune disease entity primarily driven by T cells, but likely not autoantibodies., PMID:40502578

Increased Fascin1 and Pak1 Expressions Enhance Age-Associated B-Cell Actin Cytoskeleton Remodeling and Motility., PMID:40500987

Anti-IL-6R antibody treatment changes microglial phenotype in AQP4 peptide-immunized mice, leading to suppression of myelitis severity., PMID:40403514

Expansions of circulating plasmablasts producing commensal-reactive IgA antibodies are predictors for chronic GVHD., PMID:40324063

Dendritic cell expression of MyD88 is required for rotavirus-induced B cell activation., PMID:40304491

Multiplex immunofluorescence assessment of macrophages and IL-23R in inflammatory and malignant diseases of the oral mucosa: a pilot study., PMID:40297579

TRPV1 Defends the Healthy Murine Cornea against Staphylococcus aureus Adhesion Independently of Sensory Nerve Firing., PMID:40291673

Deep immunophenotyping and clustering identifies biomarkers predictive of lymphoma in primary Sjögren disease., PMID:40290096

Lung disease in relation to unique monocyte-macrophage subpopulations induced by combined inhalant endotoxin and collagen-induced arthritis., PMID:40270956

Function of Immune Checkpoints in IgG4-Related Disease with Lacrimal Gland Involvement: Clinical Features, Serum IgG4 Level, Immunohistochemical Landscape, and Treatment Responses., PMID:40243629

T-bet+CD11c+ age-associated B cells resist BLyS- and CD20-targeted ablation in murine lupus models., PMID:40163938

Evaluation of Dendritic Cell Subpopulations Frequency in COVID-19 Patients and their Correlation with Disease Severity., PMID:40130356

Rejuvenation of Tumor-Specific T Cells via Ultrahigh DAR Antibody-Polymeric Imidazoquinoline Complexes: Coordinated Targeting of PDL1 and Efficient TLR7/8 Activation in Intratumoral Dendritic Cells., PMID:40091265

Molecular determinants of response to neoadjuvant pembrolizumab plus chemotherapy in patients with high-risk, early-stage, triple-negative breast cancer: exploratory analysis of the open-label, multicohort phase 1b KEYNOTE-173 study., PMID:40069763

IL-4 alters TLR7-induced B cell developmental program in lupus., PMID:40068727

Inflammatory and tolerogenic dendritic cells and T lymphocytes in Graves' thyroidal and orbital disease., PMID:40024060

A CLDN18.2-Targeted Nanoplatform Manipulates Magnetic Hyperthermia Spatiotemporally for Synergistic Immunotherapy in Gastric Cancer., PMID:40019387

Atypical memory B cells acquire Breg phenotypes in hepatocellular carcinoma., PMID:39998891

Properties of Monocyte-Derived Dendritic Cells Loaded With Lysates of Cancer Cells Exposed to Cytotoxic Peptides., PMID:39985347

Dysfunctional CD11c-CD21- extrafollicular memory B cells are enriched in the periphery and tumors of patients with cancer., PMID:39970232

NPRL2 gene therapy induces effective antitumor immunity in KRAS/STK11 mutant anti-PD1 resistant metastatic non-small cell lung cancer (NSCLC) in a humanized mouse model., PMID:39932765

Recent Evidence of the Role of CD4+ T Cell Subsets in IgG4-related Disease., PMID:39926068

Evaluation of B cell related markers and autoantibodies in rheumatoid arthritis patients treated with abatacept., PMID:39925810

Dual in vivo T cell depleted haploidentical hematopoietic stem cell transplantation with post-transplant cyclophosphamide and anti-thymocyte globulin as a third salvage transplant for leukocyte adhesion deficiency with graft failure: a case report., PMID:39845947

Multiplex immunohistochemistry to explore the tumor immune microenvironment in HCC patients with different GPC3 expression., PMID:39838375

Suppression of Pathological Allergen-Specific B Cells by Protein-Engineered Molecules in a Mouse Model of Chronic House Dust Mite Allergy., PMID:39769423

Tumor β-Catenin Expression Associated With Poor Prognosis to Anti-PD-1 Antibody Monotherapy in Non-small Cell Lung Cancer., PMID:39758230

Function and Regulation of Age-Associated B Cells in Diseases., PMID:39749652

Polyphenol oxidase cross-linking enhances whey protein-induced systemic food allergy by regulating miRNA in CD4+ T cells., PMID:39744957

Vaccines targeting p53 mutants elicit anti-tumor immunity., PMID:39740750

Donor HLA-DQ reactive B cells clonally expand under chronic immunosuppression and include atypical CD21 low CD27 - B cells with high-avidity germline B-cell receptors., PMID:39713394

Early decrease of T-bet+ B cells during subcutaneous belimumab predicts response to therapy in systemic lupus erythematosus patients., PMID:39643119

Nanoparticle containing recombinant excretory/secretory-24 protein of Haemonchus contortus enhanced the cellular immune responses in mice., PMID:39600880

Outcome of SARS-CoV-2 reinfection depends on genetic background in female mice., PMID:39580470

Therapeutic effects of extracellular vesicles derived from mesenchymal stem cells primed with disease-conditioned-immune cells in systemic lupus erythematosus., PMID:39558370

Toxoplasma GRA15 expression on dendritic cells inhibits B cell differentiation and antibody production., PMID:39557359

Hairy cell leukemia (HCL) and HCL-like disorders: present, emergent treatment options and future directions., PMID:39535173

Rise of a CD27- IgD- CD11c+ B cells population in kidney recipients achieving long-term graft stability under immunosuppression., PMID:39511872

B cell-intrinsic IFN-γ promotes excessive CD11c+ age-associated B cell differentiation and compromised germinal center selection in lupus mice., PMID:39503082

Ageing-Related Macrophage Polarisation in the Trigeminal Ganglion Enhances Incisional Intraoral Pain., PMID:39467109

Differences in phenotype between long-lived memory B cells against Plasmodium falciparum merozoite antigens and variant surface antigens., PMID:39466842

Allogenic MSC infusion in kidney transplantation recipients promotes within 4 hours distinct B cell and T cell phenotypes., PMID:39450174

Pregnancy-related factors induce immune tolerance through regulation of sCD83 release., PMID:39328416

18F-fluorodeoxyglucose PET-MR characterization of aortic inflammation in ApoE-/- mouse models of accelerated atherosclerosis: comparison of Western diet vs. uremia., PMID:39305349

A squalene oil emulsified MPL-A and anti-CD200/CD300a antibodies adjuvanted whole-killed Leishmania vaccine provides durable immunity against L. donovani parasites., PMID:39288578

Approbation of a Homologous Model of the Antitumor Vaccine Based on Mature Mouse Dendritic Cells to Study the Biodistribution of the Cell Product., PMID:39287724

Disturbed Complement Receptor Expression Pattern of B Cells Is Enhanced by Toll-like Receptor CD180 Ligation in Diffuse Cutaneous Systemic Sclerosis., PMID:39273179

Flow cytometric-based detection of CD80 is a useful diagnostic marker of acute myeloid leukemia in dogs., PMID:39224452

The role of M1 (CD11c) and M2 (CD163) interplay in the pathogenesis of oral submucous fibrosis and its malignant transformation: An immunohistochemical analysis., PMID:39217916

Elevated IL-15 levels in systemic lupus erythematosus: potential pathogenesis insight and therapeutic target., PMID:39217881

Datasheet
$ 170
Product specifications
50 μg 170 100 μg 280

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For research use only. Not for human or drug use.

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Anti-CD11c/ITGAX Polyclonal Antibody [PHD41101]
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