Catalog No.
PHD40201
Species reactivity
Human
Host species
Rabbit
Isotype
IgG
Clonality
Polyclonal
Immunogen
E. coli - derived recombinant Human MX2 (Met1-Asp300).
Tested applications
ELISA: 1:4000-1:8000, IHC: 1:50-1:100, WB: 1:1000-1:4000
Target
Interferon-induced GTP-binding protein Mx2,Myxovirus resistance protein 2,p78-related protein,MX2,Interferon-regulated resistance GTP-binding protein MxB
Purification
Purified by antigen affinity column.
Accession
P20592
Applications
ELISA, IHC, WB
Form
Liquid
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Stability and Storage
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Lenacapavir disrupts HIV-1 core integrity while stabilizing the capsid lattice., PMID:40168125
Profiling Humoral Immunity After Mixing and Matching COVID-19 Vaccines Using SARS-CoV-2 Variant Protein Microarrays., PMID:36787877
Evaluation Value of Allergy in Adenoid Hypertrophy Through Blood Inflammatory Cells and Total Immunoglobulin E., PMID:36473200
Species-specific transcriptomic changes upon respiratory syncytial virus infection in cotton rats., PMID:36195733
Identification and immune responses of thrombocytes in bacterial and viral infections in grass carp (Ctenopharyngodon idella)., PMID:35306178
Application of a recombinant replicase to localize the Trionyx sinensis hemorrhagic syndrome virus and evaluate its effects on antiviral genes of T. sinensis., PMID:33835763
Restriction Factor Expression in Vertically Infected Children Living With HIV-1., PMID:33395209
Sensitisation of severe asthma in different occupations: A multicentre study in China., PMID:32981215
The Ratiometric Transcript Signature MX2/GPR183 Is Consistently Associated With RTS,S-Mediated Protection Against Controlled Human Malaria Infection., PMID:32411130
Interferon-stimulated genes inhibit caprine parainfluenza virus type 3 replication in Madin-Darby bovine kidney cells., PMID:31928705
Functional study of 14-3-3 protein epsilon (YWHAE) in keratinocytes: microarray integrating bioinformatics approaches., PMID:31244373
The Effect of Furanocoumarin Derivatives on Induction of Apoptosis and Multidrug Resistance in Human Leukemic Cells., PMID:31083598
Membrane insertion and secretion of the Engrailed-2 (EN2) transcription factor by prostate cancer cells may induce antiviral activity in the stroma., PMID:30914795
HIV-1 capsids from B27/B57+ elite controllers escape Mx2 but are targeted by TRIM5α, leading to the induction of an antiviral state., PMID:30419009
Oviduct epithelium induces interferon-tau in bovine Day-4 embryos, which generates an anti-inflammatory response in immune cells., PMID:29777205
Exosomal αvβ6 integrin is required for monocyte M2 polarization in prostate cancer., PMID:29530483
A plasmid containing CpG ODN as vaccine adjuvant against grass carp reovirus in grass carp Ctenopharyngodon idella., PMID:29156818
[Distribution characteristics of serum specific IgE for inhaled allergens in children with different airway allergic diseases]., PMID:29132467
Bank vole immunoheterogeneity may limit Nephropatia Epidemica emergence in a French non-endemic region., PMID:28931451
Expression and molecular cloning of interferon stimulated genes in buffalo (Bubalus bubalis)., PMID:28708533
CORRELATION BETWEEN SPIROMETRY DATES AND SPECIAL ALLERGEN- SPECIFIC IGE IN PATIENTS WITH BRONCHIAL ASTHMA IN WEST GEORGIA., PMID:28628021
Cardiac fibroblast transcriptome analyses support a role for interferogenic, profibrotic, and inflammatory genes in anti-SSA/Ro-associated congenital heart block., PMID:28626076
BCL6 represses antiviral resistance in follicular T helper cells., PMID:28550121
Dynamic Modulation of Expression of Lentiviral Restriction Factors in Primary CD4+ T Cells following Simian Immunodeficiency Virus Infection., PMID:28100613
Change in the responsiveness of interferon-stimulated genes during early pregnancy in cows with Borna virus-1 infection., PMID:27842550
Soybean-derived Bowman-Birk Inhibitor (BBI) Inhibits HIV Replication in Macrophages., PMID:27734899
In vivo optical imaging of MMP2 immuno protein antibody: tumor uptake is associated with MMP2 activity., PMID:26923459
Restriction of HIV-1 Requires the N-Terminal Region of MxB as a Capsid-Binding Motif but Not as a Nuclear Localization Signal., PMID:26063425
A triple-arginine motif in the amino-terminal domain and oligomerization are required for HIV-1 inhibition by human MX2., PMID:25673704
Prediction of therapeutic responses to tocilizumab in patients with rheumatoid arthritis: biomarkers identified by analysis of gene expression in peripheral blood mononuclear cells using genome-wide DNA microarray., PMID:24591094
Differential antiviral activity of Mx1, Mx2 and Mx3 proteins from gilthead seabream (Sparus aurata) against Infectious Pancreatic Necrosis Virus (IPNV)., PMID:21872932
Regulation of IFN response gene activity during infliximab treatment in rheumatoid arthritis is associated with clinical response to treatment., PMID:20096109
Interferon-induced Mx proteins in brain tissue of multiple sclerosis patients., PMID:19236454
Dynamics of interferon-beta modulated mRNA biomarkers in multiple sclerosis patients with anti-interferon-beta neutralizing antibodies., PMID:16698090
Postnatal behavioral and physiological responses of piglets from gilts housed individually or in groups during gestation., PMID:16478968
Effusion cytodiagnosis of carcinosarcoma derived from the female genital tract: immunohistochemical features of MMP-7 and Ki-67 and immunofluorescence double staining analyses of eight cases., PMID:15863125
Essential role for the p40 subunit of interleukin-12 in neutrophil-mediated early host defense against pulmonary infection with Streptococcus pneumoniae: involvement of interferon-gamma., PMID:15555529
Specific and effective targeting cancer immunotherapy with a combination of three bispecific antibodies., PMID:11852114
Selective distribution of matrix metalloproteinase-3 (MMP-3) in Alzheimer's disease brain., PMID:10672313
Expression of the membrane-type 3 matrix metalloproteinase (MT3-MMP) in human brain tissues., PMID:9796998
Antiviral determinants of rat Mx GTPases map to the carboxy-terminal half., PMID:9371647
Cloning of the rainbow trout (Oncorhynchus mykiss) Mx2 and Mx3 cDNAs and characterization of trout Mx protein expression in salmon cells., PMID:9188599
Intracellular staining of Mx proteins in cells from peripheral blood, bone marrow and skin., PMID:9208807
Human MxB protein, an interferon-alpha-inducible GTPase, contains a nuclear targeting signal and is localized in the heterochromatin region beneath the nuclear envelope., PMID:8798556
Decreased P-glycoprotein expression in multidrug-sensitive and -resistant human myeloma cells induced by the cytokine leukoregulin., PMID:1356622
Mouse Mx2 protein inhibits vesicular stomatitis virus but not influenza virus., PMID:1312277
Resistance to influenza virus and vesicular stomatitis virus conferred by expression of human MxA protein., PMID:2161946
Measurement of cross-reactive properties of adriamycin derivatives by the inhibition enzyme-linked immunosorbent assay for adriamycin., PMID:2130540
Multidrug resistance in mitoxantrone-selected HL-60 leukemia cells in the absence of P-glycoprotein overexpression., PMID:2568172
For research use only. Not for human or drug use.
